| inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis A Banerjee, E Dubnau, A Quemard, V Balasubramanian, KS Um, ... Science 263 (5144), 227-230, 1994 | 1978 | 1994 |
| Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase JD McKinney, KH Zu Bentrup, EJ Muñoz-Elías, A Miczak, B Chen, ... Nature 406 (6797), 735-738, 2000 | 1715 | 2000 |
| An outbreak of tuberculosis with accelerated progression among persons infected with the Human Immunodeficiency Virus: an analysis using restriction-fragment—length polymorphisms CL Daley, PM Small, GF Schecter, GK Schoolnik, RA McAdam, ... New England journal of medicine 326 (4), 231-235, 1992 | 1387 | 1992 |
| Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis DA Rozwarski, GA Grant, DHR Barton, WR Jacobs, JC Sacchettini Science 279 (5347), 98-102, 1998 | 891 | 1998 |
| Mechanisms of drug resistance in Mycobacterium tuberculosis Y Zhang, WR Jacobs Jr, C Vilchèze Tuberculosis and the tubercle bacillus, 115-140, 2005 | 887 | 2005 |
| The primary mechanism of attenuation of bacillus Calmette–Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue T Hsu, SM Hingley-Wilson, B Chen, M Chen, AZ Dai, PM Morin, CB Marks, ... Proceedings of the National Academy of Sciences 100 (21), 12420-12425, 2003 | 886 | 2003 |
| Complex lipid determines tissue-specific replication of Mycobacterium tuberculosis in mice JS Cox, B Chen, M McNeil, WR Jacobs Nature 402 (6757), 79-83, 1999 | 878 | 1999 |
| A novel mycolic acid cyclopropane synthetase is required for cording, persistence, and virulence of Mycobacterium tuberculosis MS Glickman, JS Cox, WR Jacobs Jr Molecular cell 5 (4), 717-727, 2000 | 829 | 2000 |
| Origins of highly mosaic mycobacteriophage genomes ML Pedulla, ME Ford, JM Houtz, T Karthikeyan, C Wadsworth, JA Lewis, ... Cell 113 (2), 171-182, 2003 | 783 | 2003 |
| Specialized transduction: an efficient method for generating marked and unmarked targeted gene disruptions in Mycobacterium tuberculosis, M. bovis BCG and M. smegmatis S Bardarov, S Bardarov Jr, MS Pavelka Jr, V Sambandamurthy, M Larsen, ... Microbiology 148 (10), 3007-3017, 2002 | 717 | 2002 |
| Cloning and nucleotide sequence of Mycobacterium tuberculosis gyrA and gyrB genes and detection of quinolone resistance mutations. HE Takiff, L Salazar, C Guerrero, W Philipp, WM Huang, B Kreiswirth, ... Antimicrobial agents and chemotherapy 38 (4), 773-780, 1994 | 712 | 1994 |
| The emb operon, a gene cluster of Mycobacterium tuberculosis involved in resistance to ethambutol A Telenti, WJ Philipp, S Sreevatsan, C Bernasconi, KE Stockbauer, ... Nature medicine 3 (5), 567-570, 1997 | 685 | 1997 |
| Rapid assessment of drug susceptibilities of Mycobacterium tuberculosis by means of luciferase reporter phages WR Jacobs, RG Barletta, R Udani, J Chan, G Kalkut, G Sosne, T Kieser, ... Science 260 (5109), 819-822, 1993 | 616 | 1993 |
| Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug‐tolerant bacteria AK Ojha, AD Baughn, D Sambandan, T Hsu, X Trivelli, Y Guerardel, ... Molecular microbiology 69 (1), 164-174, 2008 | 591 | 2008 |
| Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis A Dessen, A Quemard, JS Blanchard, WR Jacobs, JC Sacchettini Science 267 (5204), 1638-1641, 1995 | 583 | 1995 |
| Efficient allelic exchange and transposon mutagenesis in Mycobacterium tuberculosis V Pelicic, M Jackson, JM Reyrat, WR Jacobs, B Gicquel, C Guilhot Proceedings of the National Academy of Sciences 94 (20), 10955-10960, 1997 | 556 | 1997 |
| Microbial pathogenesis of Mycobacterium tuberculosis: dawn of a discipline MS Glickman, WR Jacobs Cell 104 (4), 477-485, 2001 | 546 | 2001 |
| [25] Genetic systems for mycobacteria WR Jacobs Jr, GV Kalpana, JD Cirillo, L Pascopella, SB Snapper, ... Methods in enzymology 204, 537-555, 1991 | 542 | 1991 |
| Site-specific integration of mycobacteriophage L5: integration-proficient vectors for Mycobacterium smegmatis, Mycobacterium tuberculosis, and bacille Calmette-Guerin. MH Lee, L Pascopella, WR Jacobs, GF Hatfull Proceedings of the National Academy of Sciences 88 (8), 3111-3115, 1991 | 534 | 1991 |
| Ethambutol resistance in Mycobacterium tuberculosis: critical role of embB mutations. S Sreevatsan, KE Stockbauer, XI Pan, BN Kreiswirth, SL Moghazeh, ... Antimicrobial agents and chemotherapy 41 (8), 1677-1681, 1997 | 524 | 1997 |
