Andrea Sottoriva
Andrea Sottoriva
Verified email at icr.ac.uk - Homepage
Title
Cited by
Cited by
Year
Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
A Sottoriva, I Spiteri, SGM Piccirillo, A Touloumis, VP Collins, JC Marioni, ...
Proceedings of the National Academy of Sciences 110 (10), 4009-4014, 2013
10902013
ANTARES: the first undersea neutrino telescope
M Ageron, JA Aguilar, I Al Samarai, A Albert, F Ameli, M André, ...
Nuclear Instruments and Methods in Physics Research Section A: Accelerators …, 2011
6982011
A Big Bang model of human colorectal tumor growth
A Sottoriva, H Kang, Z Ma, TA Graham, MP Salomon, J Zhao, P Marjoram, ...
Nature genetics 47 (3), 209, 2015
5882015
The shaping and functional consequences of the microRNA landscape in breast cancer
H Dvinge, A Git, S Gräf, M Salmon-Divon, C Curtis, A Sottoriva, Y Zhao, ...
Nature 497 (7449), 378-382, 2013
3592013
Identification of neutral tumor evolution across cancer types
MJ Williams, B Werner, CP Barnes, TA Graham, A Sottoriva
Nature genetics 48 (3), 238, 2016
3172016
Patient-derived organoids model treatment response of metastatic gastrointestinal cancers
G Vlachogiannis, S Hedayat, A Vatsiou, Y Jamin, J Fernández-Mateos, ...
Science 359 (6378), 920-926, 2018
2692018
Defining stem cell dynamics in models of intestinal tumor initiation
L Vermeulen, E Morrissey, M Van Der Heijden, AM Nicholson, A Sottoriva, ...
Science 342 (6161), 995-998, 2013
2642013
Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity
A Sottoriva, JJC Verhoeff, T Borovski, SK McWeeney, L Naumov, ...
Cancer research 70 (1), 46-56, 2010
1752010
A multiphysics and multiscale software environment for modeling astrophysical systems
SP Zwart, S McMillan, S Harfst, D Groen, M Fujii, BÓ Nualláin, E Glebbeek, ...
New Astronomy 14 (4), 369-378, 2009
1612009
Cancer evolution and the limits of predictability in precision cancer medicine
KA Lipinski, LJ Barber, MN Davies, M Ashenden, A Sottoriva, M Gerlinger
Trends in cancer 2 (1), 49-63, 2016
1522016
Classifying the evolutionary and ecological features of neoplasms
CC Maley, A Aktipis, TA Graham, A Sottoriva, AM Boddy, M Janiszewska, ...
Nature Reviews Cancer 17 (10), 605-619, 2017
1302017
Single-molecule genomic data delineate patient-specific tumor profiles and cancer stem cell organization
A Sottoriva, I Spiteri, D Shibata, C Curtis, S Tavaré
Cancer research 73 (1), 41-49, 2013
802013
Current challenges in glioblastoma: intratumour heterogeneity, residual disease, and models to predict disease recurrence
HP Ellis, M Greenslade, B Powell, I Spiteri, A Sottoriva, KM Kurian
Frontiers in oncology 5, 251, 2015
782015
Quantification of subclonal selection in cancer from bulk sequencing data
MJ Williams, B Werner, T Heide, C Curtis, CP Barnes, A Sottoriva, ...
Nature genetics 50 (6), 895-903, 2018
772018
Between-region genetic divergence reflects the mode and tempo of tumor evolution
R Sun, Z Hu, A Sottoriva, TA Graham, A Harpak, Z Ma, JM Fischer, ...
Nature genetics 49 (7), 1015-1024, 2017
662017
Modeling evolutionary dynamics of epigenetic mutations in hierarchically organized tumors
A Sottoriva, L Vermeulen, S Tavaré
PLoS computational biology 7 (5), 2011
652011
Longitudinal liquid biopsy and mathematical modeling of clonal evolution forecast time to treatment failure in the PROSPECT-C phase II colorectal cancer clinical trial
KH Khan, D Cunningham, B Werner, G Vlachogiannis, I Spiteri, T Heide, ...
Cancer discovery 8 (10), 1270-1285, 2018
612018
Resolving genetic heterogeneity in cancer
S Turajlic, A Sottoriva, T Graham, C Swanton
Nature Reviews Genetics 20 (7), 404-416, 2019
552019
EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation
E Eskilsson, GV Rosland, KM Talasila, S Knappskog, O Keunen, ...
Neuro-oncology 18 (12), 1644-1655, 2016
452016
Exploring cancer stem cell niche directed tumor growth
A Sottoriva, PMA Sloot, JP Medema, L Vermeulen
Cell Cycle 9 (8), 1472-1479, 2010
412010
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