Fang He
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CGG repeat-associated translation mediates neurodegeneration in fragile X tremor ataxia syndrome
PK Todd, SY Oh, A Krans, F He, C Sellier, M Frazer, AJ Renoux, K Chen, ...
Neuron 78 (3), 440-455, 2013
Discovery of novel DENN proteins: implications for the evolution of eukaryotic intracellular membrane structures and human disease
D Zhang, LM Iyer, F He, L Aravind
Frontiers in Genetics 3, 283, 0
Sequestration of DROSHA and DGCR8 by expanded CGG RNA repeats alters microRNA processing in fragile X-associated tremor/ataxia syndrome
C Sellier, F Freyermuth, R Tabet, T Tran, F He, F Ruffenach, V Alunni, ...
Cell reports 3 (3), 869-880, 2013
Translation of expanded CGG repeats into FMRpolyG is pathogenic and may contribute to fragile X tremor ataxia syndrome
C Sellier, RAM Buijsen, F He, S Natla, L Jung, P Tropel, A Gaucherot, ...
Neuron 93 (2), 331-347, 2017
RAN translation at CGG repeats induces ubiquitin proteasome system impairment in models of fragile X-associated tremor ataxia syndrome
SY Oh, F He, A Krans, M Frazer, JP Taylor, HL Paulson, PK Todd
Human molecular genetics 24 (15), 4317-4326, 2015
C9 ORF 72 expansion in a family with bipolar disorder
MH Meisler, AE Grant, JM Jones, GM Lenk, F He, PK Todd, M Kamali, ...
Bipolar disorders 15 (3), 326-332, 2013
TDP-43 suppresses CGG repeat-induced neurotoxicity through interactions with HnRNP A2/B1
F He, A Krans, BD Freibaum, JP Taylor, PK Todd
Human molecular genetics 23 (19), 5036-5051, 2014
Caspase‐mediated Degradation of PPARγ Proteins in Adipocytes
F He, JA Doucet, JM Stephens
Obesity 16 (8), 1735-1741, 2008
Epigenetics in nucleotide repeat expansion disorders
F He, PK Todd
Seminars in neurology 31 (05), 470-483, 2011
Small Molecule Recognition and Tools to Study Modulation of r(CGG)exp in Fragile X-Associated Tremor Ataxia Syndrome
WY Yang, F He, RL Strack, SY Oh, M Frazer, SR Jaffrey, PK Todd, ...
ACS chemical biology 11 (9), 2456-2465, 2016
DDX3X and specific initiation factors modulate FMR1 repeat‐associated non‐AUG‐initiated translation
AE Linsalata, F He, AM Malik, MR Glineburg, KM Green, S Natla, ...
EMBO reports 20 (9), e47498, 2019
Drosophila delta-1-pyrroline-5-carboxylate dehydrogenase (P5CDh) is required for proline breakdown and mitochondrial integrity—establishing a fly model for human type II …
F He, PJ DiMario
Mitochondrion 11 (3), 397-404, 2011
Induction of SOCS-3 is insufficient to confer IRS-1 protein degradation in 3T3-L1 adipocytes
F He, JM Stephens
Biochemical and biophysical research communications 344 (1), 95-98, 2006
Deletion of Drosophila Nopp140 induces subcellular ribosomopathies
F He, A James, H Raje, H Ghaffari, P DiMario
Chromosoma 124 (2), 191-208, 2015
Structure and function of Nopp140 and Treacle
F He, P DiMario
The nucleolus, 253-278, 2011
Degradation of STAT5 proteins in 3T3-L1 adipocytes is induced by TNF-α and cycloheximide in a manner independent of STAT5A activation
ZE Floyd, BM Segura, F He, JM Stephens
American Journal of Physiology-Endocrinology and Metabolism 292 (2), E461-E468, 2007
Large-scale screening of disease model through ENU mutagenesis in mice
F He, Z Wang, J Zhao, J Bao, J Ding, H Ruan, Q Xie, Z Zhang, X Gao
Chinese Science Bulletin 48 (24), 2665-2671, 2003
The carboxyl termini of RAN translated GGGGCC nucleotide repeat expansions modulate toxicity in models of ALS/FTD
F He, BN Flores, A Krans, M Frazer, S Natla, S Niraula, O Adefioye, ...
Acta neuropathologica communications 8 (1), 1-17, 2020
Screening for novel hexanucleotide repeat expansions at ALS-and FTD-associated loci
F He, JM Jones, C Figueroa-Romero, D Zhang, EL Feldman, SA Goutman, ...
Neurology Genetics 2 (3), 2016
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Articles 1–19