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David Dilworth
David Dilworth
BlueRock Therapeutics
Verified email at utoronto.ca - Homepage
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Cited by
Cited by
Year
Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response
MM Szewczyk, Y Ishikawa, S Organ, N Sakai, F Li, L Halabelian, S Ackloo, ...
Nature communications 11 (1), 2396, 2020
832020
Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3
J Böttcher, D Dilworth, U Reiser, RA Neumüller, M Schleicher, ...
Nature chemical biology 15 (8), 822-829, 2019
742019
A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization
D Dilworth, RP Hanley, R Ferreira de Freitas, A Allali-Hassani, M Zhou, ...
Nature chemical biology 18 (1), 56-63, 2022
422022
Paternal Genome Elimination in Liposcelis Booklice (Insecta: Psocodea)
CN Hodson, PT Hamilton, D Dilworth, CJ Nelson, CI Curtis, SJ Perlman
Genetics 206 (2), 1091-1100, 2017
412017
Discovery of small-molecule antagonists of the PWWP domain of NSD2
R Ferreira de Freitas, Y Liu, MM Szewczyk, N Mehta, F Li, D McLeod, ...
Journal of medicinal chemistry 64 (3), 1584-1592, 2021
362021
The prolyl isomerase, FKBP25, interacts with RNA-engaged nucleolin and the pre-60S ribosomal subunit
G Gudavicius, D Dilworth, JJ Serpa, N Sessler, EV Petrotchenko, ...
Rna 20 (7), 1014-1022, 2014
332014
Discovery of a chemical probe for PRDM9
A Allali-Hassani, MM Szewczyk, D Ivanochko, SL Organ, J Bok, JSY Ho, ...
Nature communications 10 (1), 5759, 2019
302019
Targeting protein methylation: from chemical tools to precision medicines
D Dilworth, D Barsyte-Lovejoy
Cellular and molecular life sciences 76, 2967-2985, 2019
282019
The prolyl isomerase FKBP25 regulates microtubule polymerization impacting cell cycle progression and genomic stability
D Dilworth, G Gudavicius, X Xu, AKJ Boyce, C O’Sullivan, JJ Serpa, ...
Nucleic Acids Research 46 (5), 2459-2478, 2018
272018
The roles of peptidyl-proline isomerases in gene regulation
D Dilworth, G Gudavicius, A Leung, CJ Nelson
Biochemistry and Cell Biology 90 (1), 55-69, 2011
272011
Discovery of a potent and selective fragment-like inhibitor of methyllysine reader protein spindlin 1 (SPIN1)
Y Xiong, H Greschik, C Johansson, L Seifert, J Bacher, K Park, N Babault, ...
Journal of medicinal chemistry 62 (20), 8996-9007, 2019
232019
The basic tilted helix bundle domain of the prolyl isomerase FKBP25 is a novel double-stranded RNA binding module
D Dilworth, SK Upadhyay, P Bonnafous, AB Edoo, S Bourbigot, ...
Nucleic Acids Research 45 (20), 11989-12004, 2017
182017
Pharmacological targeting of a PWWP domain demonstrates cooperative control of NSD2 localization
D Dilworth, RP Hanley, RF de Freitas, A Allali-Hassani, M Zhou, N Mehta, ...
bioRxiv, 2021.03. 05.433782, 2021
72021
FKBP25 participates in DNA double-strand break repair
D Dilworth, F Gong, K Miller, CJ Nelson
Biochemistry and Cell Biology 98 (1), 42-49, 2020
72020
Characterization of inv (3) cell line OCI-AML-20 with stroma-dependent CD34 expression
GM Luciani, L Xie, D Dilworth, A Tierens, Y Moskovitz, A Murison, ...
Experimental hematology 69, 27-36, 2019
42019
Rapid identification of chemical genetic interactions in Saccharomyces cerevisiae
D Dilworth, CJ Nelson
JoVE (Journal of Visualized Experiments), e52345, 2015
22015
Genetic dissection of the redundant and divergent functions of histone chaperone paralogs in yeast
N Savic, SP Shortill, M Bilenky, D Dilworth, M Hirst, CJ Nelson
bioRxiv, 586347, 2019
12019
Guiding COMPASS: Dpy-30 positions SET1/MLL epigenetic signaling
D Dilworth, CH Arrowsmith
Structure 26 (12), 1567-1570, 2018
12018
UVicSPACE: Research & Learning Repository
CN Hodson, PT Hamilton, D Dilworth, CJ Nelson, CI Curtis, SJ Perlman, ...
2017
A nuclear prolyl isomerase enzyme participates in double strand break repair
D Dilworth, G Gudavicius, CJ Nelson
Biochemistry and Cell Biology 95 (2), 182-184, 2017
2017
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