Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response MM Szewczyk, Y Ishikawa, S Organ, N Sakai, F Li, L Halabelian, S Ackloo, ... Nature communications 11 (1), 2396, 2020 | 83 | 2020 |
Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3 J Böttcher, D Dilworth, U Reiser, RA Neumüller, M Schleicher, ... Nature chemical biology 15 (8), 822-829, 2019 | 74 | 2019 |
A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization D Dilworth, RP Hanley, R Ferreira de Freitas, A Allali-Hassani, M Zhou, ... Nature chemical biology 18 (1), 56-63, 2022 | 42 | 2022 |
Paternal Genome Elimination in Liposcelis Booklice (Insecta: Psocodea) CN Hodson, PT Hamilton, D Dilworth, CJ Nelson, CI Curtis, SJ Perlman Genetics 206 (2), 1091-1100, 2017 | 41 | 2017 |
Discovery of small-molecule antagonists of the PWWP domain of NSD2 R Ferreira de Freitas, Y Liu, MM Szewczyk, N Mehta, F Li, D McLeod, ... Journal of medicinal chemistry 64 (3), 1584-1592, 2021 | 36 | 2021 |
The prolyl isomerase, FKBP25, interacts with RNA-engaged nucleolin and the pre-60S ribosomal subunit G Gudavicius, D Dilworth, JJ Serpa, N Sessler, EV Petrotchenko, ... Rna 20 (7), 1014-1022, 2014 | 33 | 2014 |
Discovery of a chemical probe for PRDM9 A Allali-Hassani, MM Szewczyk, D Ivanochko, SL Organ, J Bok, JSY Ho, ... Nature communications 10 (1), 5759, 2019 | 30 | 2019 |
Targeting protein methylation: from chemical tools to precision medicines D Dilworth, D Barsyte-Lovejoy Cellular and molecular life sciences 76, 2967-2985, 2019 | 28 | 2019 |
The prolyl isomerase FKBP25 regulates microtubule polymerization impacting cell cycle progression and genomic stability D Dilworth, G Gudavicius, X Xu, AKJ Boyce, C O’Sullivan, JJ Serpa, ... Nucleic Acids Research 46 (5), 2459-2478, 2018 | 27 | 2018 |
The roles of peptidyl-proline isomerases in gene regulation D Dilworth, G Gudavicius, A Leung, CJ Nelson Biochemistry and Cell Biology 90 (1), 55-69, 2011 | 27 | 2011 |
Discovery of a potent and selective fragment-like inhibitor of methyllysine reader protein spindlin 1 (SPIN1) Y Xiong, H Greschik, C Johansson, L Seifert, J Bacher, K Park, N Babault, ... Journal of medicinal chemistry 62 (20), 8996-9007, 2019 | 23 | 2019 |
The basic tilted helix bundle domain of the prolyl isomerase FKBP25 is a novel double-stranded RNA binding module D Dilworth, SK Upadhyay, P Bonnafous, AB Edoo, S Bourbigot, ... Nucleic Acids Research 45 (20), 11989-12004, 2017 | 18 | 2017 |
Pharmacological targeting of a PWWP domain demonstrates cooperative control of NSD2 localization D Dilworth, RP Hanley, RF de Freitas, A Allali-Hassani, M Zhou, N Mehta, ... bioRxiv, 2021.03. 05.433782, 2021 | 7 | 2021 |
FKBP25 participates in DNA double-strand break repair D Dilworth, F Gong, K Miller, CJ Nelson Biochemistry and Cell Biology 98 (1), 42-49, 2020 | 7 | 2020 |
Characterization of inv (3) cell line OCI-AML-20 with stroma-dependent CD34 expression GM Luciani, L Xie, D Dilworth, A Tierens, Y Moskovitz, A Murison, ... Experimental hematology 69, 27-36, 2019 | 4 | 2019 |
Rapid identification of chemical genetic interactions in Saccharomyces cerevisiae D Dilworth, CJ Nelson JoVE (Journal of Visualized Experiments), e52345, 2015 | 2 | 2015 |
Genetic dissection of the redundant and divergent functions of histone chaperone paralogs in yeast N Savic, SP Shortill, M Bilenky, D Dilworth, M Hirst, CJ Nelson bioRxiv, 586347, 2019 | 1 | 2019 |
Guiding COMPASS: Dpy-30 positions SET1/MLL epigenetic signaling D Dilworth, CH Arrowsmith Structure 26 (12), 1567-1570, 2018 | 1 | 2018 |
UVicSPACE: Research & Learning Repository CN Hodson, PT Hamilton, D Dilworth, CJ Nelson, CI Curtis, SJ Perlman, ... | | 2017 |
A nuclear prolyl isomerase enzyme participates in double strand break repair D Dilworth, G Gudavicius, CJ Nelson Biochemistry and Cell Biology 95 (2), 182-184, 2017 | | 2017 |