Francis Lynn
Francis Lynn
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Serotonin regulates pancreatic beta cell mass during pregnancy
H Kim, Y Toyofuku, FC Lynn, E Chak, T Uchida, H Mizukami, Y Fujitani, ...
Nature medicine 16 (7), 804-808, 2010
Dipeptidyl peptidase IV inhibitor treatment stimulates β-cell survival and islet neogenesis in streptozotocin-induced diabetic rats
JA Pospisilik, J Martin, T Doty, JA Ehses, N Pamir, FC Lynn, S Piteau, ...
Diabetes 52 (3), 741-750, 2003
HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain
MA Kalchman, HB Koide, K McCutcheon, RK Graham, K Nichol, ...
Nature genetics 16 (1), 44-53, 1997
MicroRNA expression is required for pancreatic islet cell genesis in the mouse
FC Lynn, P Skewes-Cox, Y Kosaka, MT McManus, BD Harfe, MS German
Diabetes 56 (12), 2938-2945, 2007
Rfx6 directs islet formation and insulin production in mice and humans
SB Smith, HQ Qu, N Taleb, NY Kishimoto, DW Scheel, Y Lu, AM Patch, ...
Nature 463 (7282), 775-780, 2010
Defective glucose-dependent insulinotropic polypeptide receptor expression in diabetic fatty Zucker rats
FC Lynn, N Pamir, EHC Ng, CHS McIntosh, TJ Kieffer, RA Pederson
Diabetes 50 (5), 1004-1011, 2001
Sox9 coordinates a transcriptional network in pancreatic progenitor cells
FC Lynn, SB Smith, ME Wilson, KY Yang, N Nekrep, MS German
Proceedings of the National Academy of Sciences 104 (25), 10500-10505, 2007
Meta-regulation: microRNA regulation of glucose and lipid metabolism
FC Lynn
Trends in Endocrinology & Metabolism 20 (9), 452-459, 2009
Reduced insulin production relieves endoplasmic reticulum stress and induces β cell proliferation
M Szabat, MM Page, E Panzhinskiy, S Skovsų, M Mojibian, ...
Cell metabolism 23 (1), 179-193, 2016
Characterization of polyhormonal insulin-producing cells derived in vitro from human embryonic stem cells
JE Bruin, S Erener, J Vela, X Hu, JD Johnson, HT Kurata, FC Lynn, ...
Stem cell research 12 (1), 194-208, 2014
Glucose-dependent insulinotropic polypeptide receptor null mice exhibit compensatory changes in the enteroinsular axis
N Pamir, FC Lynn, AMJ Buchan, J Ehses, SA Hinke, JA Pospisilik, ...
American Journal of Physiology-Endocrinology and Metabolism 284 (5), E931-E939, 2003
Improved glucose tolerance in rats treated with the dipeptidyl peptidase IV (CD26) inhibitor Ile-thiazolidide
RP Pauly, HU Demuth, F Rosche, J Schmidt, HA White, F Lynn, ...
Metabolism 48 (3), 385-389, 1999
The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreas
ME Wilson, KY Yang, A Kalousova, J Lau, Y Kosaka, FC Lynn, J Wang, ...
Diabetes 54 (12), 3402-3409, 2005
Reversal of islet GIP receptor down-regulation and resistance to GIP by reducing hyperglycemia in the Zucker rat
S Piteau, A Olver, SJ Kim, K Winter, JA Pospisilik, F Lynn, S Manhart, ...
Biochemical and biophysical research communications 362 (4), 1007-1012, 2007
A novel pathway for regulation of glucose‐dependent insulinotropic polypeptide receptor expression in β‐cells
FC Lynn, SA Thompson, JA Pospisilik, JA Ehses, SA Hinke, N Pamir, ...
The FASEB Journal 17 (1), 91-93, 2003
The polycomb-dependent epigenome controls β cell dysfunction, dedifferentiation, and diabetes
TTH Lu, S Heyne, E Dror, E Casas, L Leonhardt, T Boenke, CH Yang, ...
Cell metabolism 27 (6), 1294-1308. e7, 2018
Mouse let-7 miRNA populations exhibit RNA editing that is constrained in the 5′-seed/cleavage/anchor regions and stabilize predicted mmu-let-7a: mRNA duplexes
JG Reid, AK Nagaraja, FC Lynn, RB Drabek, DM Muzny, CA Shaw, ...
Genome research 18 (10), 1571-1581, 2008
Maintenance of β-cell maturity and plasticity in the adult pancreas: developmental biology concepts in adult physiology
M Szabat, FC Lynn, BG Hoffman, TJ Kieffer, DW Allan, JD Johnson
Diabetes 61 (6), 1365-1371, 2012
Glucose-dependent insulinotropic polypeptide stimulation of lipolysis in differentiated 3T3-L1 cells: wortmannin-sensitive inhibition by insulin
CHS McIntosh, I Bremsak, FC Lynn, R Gill, SA Hinke, R Gelling, C Nian, ...
Endocrinology 140 (1), 398-404, 1999
Single-cell transcriptome profiling of mouse and hESC-derived pancreatic progenitors
NAJ Krentz, MYY Lee, EE Xu, SLJ Sproul, A Maslova, S Sasaki, FC Lynn
Stem cell reports 11 (6), 1551-1564, 2018
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