Islet prohormone processing in health and disease YC Chen, AJ Taylor, CB Verchere Diabetes, Obesity and Metabolism 20, 64-76, 2018 | 78 | 2018 |
Glucocorticoid-induced suppression of β-cell proliferation is mediated by Mig6 ES Colvin, HY Ma, YC Chen, AM Hernandez, PT Fueger Endocrinology 154 (3), 1039-1046, 2013 | 52 | 2013 |
Measurement of pro-islet amyloid polypeptide (1–48) in diabetes and islet transplants JA Courtade, AM Klimek-Abercrombie, YC Chen, N Patel, PYT Lu, ... The Journal of Clinical Endocrinology & Metabolism 102 (7), 2595-2603, 2017 | 42 | 2017 |
Islet macrophages shift to a reparative state following pancreatic beta-cell death and are a major source of islet insulin-like growth factor-1 D Nackiewicz, M Dan, M Speck, SZ Chow, YC Chen, JA Pospisilik, ... Iscience 23 (1), 2020 | 39 | 2020 |
Upregulation of p21 activates the intrinsic apoptotic pathway in β-cells AM Hernandez, ES Colvin, YC Chen, SL Geiss, LE Eller, PT Fueger American Journal of Physiology-Endocrinology and Metabolism 304 (12), E1281 …, 2013 | 34 | 2013 |
Mitogen-inducible gene 6 triggers apoptosis and exacerbates ER stress-induced β-cell death YC Chen, ES Colvin, BF Maier, RG Mirmira, PT Fueger Molecular endocrinology 27 (1), 162-171, 2013 | 33 | 2013 |
The β cell in diabetes: integrating biomarkers with functional measures SE Kahn, YC Chen, N Esser, AJ Taylor, DH van Raalte, S Zraika, ... Endocrine reviews 42 (5), 528-583, 2021 | 30 | 2021 |
Altered β-cell prohormone processing and secretion in type 1 diabetes T Rodriguez-Calvo, YC Chen, CB Verchere, L Haataja, P Arvan, P Leete, ... Diabetes 70 (5), 1038-1050, 2021 | 25 | 2021 |
Mig6 haploinsufficiency protects mice against streptozotocin-induced diabetes YC Chen, ES Colvin, KE Griffin, BF Maier, PT Fueger Diabetologia 57, 2066-2075, 2014 | 20 | 2014 |
Depletion of PAK1 enhances ubiquitin-mediated survivin degradation in pancreatic β-cells YC Chen, PT Fueger, Z Wang Islets 5 (1), 22-28, 2013 | 16 | 2013 |
PAM haploinsufficiency does not accelerate the development of diet-and human IAPP-induced diabetes in mice YC Chen, RE Mains, BA Eipper, BG Hoffman, TA Czyzyk, JE Pintar, ... Diabetologia 63, 561-576, 2020 | 14 | 2020 |
Assessing replication and beta cell function in adenovirally-transduced isolated rodent islets PT Fueger, AM Hernandez, YC Chen, ES Colvin JoVE (Journal of Visualized Experiments), e4080, 2012 | 13 | 2012 |
SORLA mediates endocytic uptake of proIAPP and protects against islet amyloid deposition AZL Shih, YC Chen, T Speckmann, E Søndergaard, A Schürmann, ... Molecular Metabolism 65, 101585, 2022 | 6 | 2022 |
Elevated islet prohormone ratios as indicators of insulin dependency in auto-islet transplant recipients YC Chen, AM Klimek-Abercrombie, KJ Potter, LP Pallo, G Soukhatcheva, ... American Journal of Transplantation 22 (8), 1992-2005, 2022 | 3 | 2022 |
Beta‐cell prohormone convertase 1/3 plays a larger role in glucose homeostasis than beta‐cell prohormone convertase 2 in mice AJ Taylor, YC Chen, CB Verchere The FASEB Journal 34 (S1), 1-1, 2020 | 3 | 2020 |
Mitogen‐inducible gene 6 potentiates glucolipotoxicity‐induced pancreatic beta cell death YC Chen, ES Colvin, PT Fueger The FASEB Journal 27, lb743-lb743, 2013 | 2 | 2013 |
Glucolipotoxicity-induced Mig6 desensitizes EGFR signaling and promotes pancreatic beta cell death YC Chen, AJ Lutkewitte, HD Basavarajappa, PT Fueger bioRxiv, 2020.11. 24.380279, 2020 | 1 | 2020 |
Deletion of carboxypeptidase E in beta cells disrupts proinsulin processing and alters beta cell identity in mice YC Chen, AJ Taylor, JM Fulcher, AC Swensen, XQ Dai, M Komba, ... Diabetes 72 (9), 1277-1288, 2023 | | 2023 |
Mig6 decreases hepatic EGFR activation and survival during saturated fatty acid-induced endoplasmic reticulum stress AJ Lutkewitte, YC Chen, JL Hansen, PT Fueger bioRxiv, 2020.11. 24.380527, 2020 | | 2020 |
Correction to: PAM haploinsufficiency does not accelerate the development of diet and human IAPP-induced diabetes in mice C Yi-Chun, RE Mains, BA Eipper, BG Hoffman, TA Czyzyk, JE Pintar, ... Diabetologia 63 (5), 1090-1090, 2020 | | 2020 |