Follow
Adam Shlien
Adam Shlien
Scientist, Hospital for Sick Children
Verified email at sickkids.ca
Title
Cited by
Cited by
Year
Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden
ZR Chalmers, CF Connelly, D Fabrizio, L Gay, SM Ali, R Ennis, A Schrock, ...
Genome medicine 9, 1-14, 2017
31762017
Mutational processes molding the genomes of 21 breast cancers
S Nik-Zainal, LB Alexandrov, DC Wedge, P Van Loo, CD Greenman, ...
Cell 149 (5), 979-993, 2012
21502012
Clinical and biological implications of driver mutations in myelodysplastic syndromes
E Papaemmanuil, M Gerstung, L Malcovati, S Tauro, G Gundem, ...
Blood, The Journal of the American Society of Hematology 122 (22), 3616-3627, 2013
20942013
A high-resolution recombination map of the human genome
A Kong, DF Gudbjartsson, J Sainz, GM Jonsdottir, SA Gudjonsson, ...
Nature genetics 31 (3), 241-247, 2002
20382002
The life history of 21 breast cancers
S Nik-Zainal, P Van Loo, DC Wedge, LB Alexandrov, CD Greenman, ...
Cell 149 (5), 994-1007, 2012
16102012
Somatic SF3B1 Mutation in Myelodysplasia with Ring Sideroblasts
E Papaemmanuil, M Cazzola, J Boultwood, L Malcovati, P Vyas, D Bowen, ...
New England Journal of Medicine 365 (15), 1384-1395, 2011
14762011
Immune checkpoint inhibition for hypermutant glioblastoma multiforme resulting from germline biallelic mismatch repair deficiency
E Bouffet, V Larouche, BB Campbell, D Merico, R De Borja, M Aronson, ...
Journal of clinical oncology 34 (19), 2206-2211, 2016
8852016
Comprehensive analysis of hypermutation in human cancer
BB Campbell, N Light, D Fabrizio, M Zatzman, F Fuligni, R de Borja, ...
Cell 171 (5), 1042-1056. e10, 2017
7532017
Copy number variations and cancer
A Shlien, D Malkin
Genome medicine 1, 1-9, 2009
4742009
Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes
JMC Tubio, Y Li, YS Ju, I Martincorena, SL Cooke, M Tojo, G Gundem, ...
Science 345 (6196), 1251343, 2014
4582014
Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study
A Villani, U Tabori, J Schiffman, A Shlien, J Beyene, H Druker, ...
The lancet oncology 12 (6), 559-567, 2011
4302011
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer
YS Ju, LB Alexandrov, M Gerstung, I Martincorena, S Nik-Zainal, ...
elife 3, e02935, 2014
4252014
Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers
A Shlien, BB Campbell, R De Borja, LB Alexandrov, D Merico, D Wedge, ...
Nature genetics 47 (3), 257-262, 2015
3962015
Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer
S Nik-Zainal, DC Wedge, LB Alexandrov, M Petljak, AP Butler, N Bolli, ...
Nature genetics 46 (5), 487-491, 2014
3202014
BRAF Mutation and CDKN2A Deletion Define a Clinically Distinct Subgroup of Childhood Secondary High-Grade Glioma
M Mistry, N Zhukova, D Merico, P Rakopoulos, R Krishnatry, M Shago, ...
Journal of clinical oncology 33 (9), 1015-1022, 2015
3082015
Signatures of copy number alterations in human cancer
CD Steele, A Abbasi, SMA Islam, AL Bowes, A Khandekar, K Haase, ...
Nature 606 (7916), 984-991, 2022
3002022
Whole exome sequencing of adenoid cystic carcinoma
PJ Stephens, HR Davies, Y Mitani, P Van Loo, A Shlien, PS Tarpey, ...
The Journal of clinical investigation 123 (7), 2965-2968, 2013
2902013
Mutational signatures of ionizing radiation in second malignancies
S Behjati, G Gundem, DC Wedge, ND Roberts, PS Tarpey, SL Cooke, ...
Nature communications 7 (1), 1-8, 2016
2732016
Excessive genomic DNA copy number variation in the Li–Fraumeni cancer predisposition syndrome
A Shlien, U Tabori, CR Marshall, M Pienkowska, L Feuk, A Novokmet, ...
Proceedings of the National Academy of Sciences 105 (32), 11264-11269, 2008
2392008
TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors
U Tabori, A Shlien, B Baskin, S Levitt, P Ray, N Alon, C Hawkins, ...
Journal of clinical oncology 28 (12), 1995-2001, 2010
2332010
The system can't perform the operation now. Try again later.
Articles 1–20