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David R Edgell
David R Edgell
Professor of Biochemistry, University of Western Ontario, London ON
Verified email at uwo.ca
Title
Cited by
Cited by
Year
Unifying the analysis of high-throughput sequencing datasets: characterizing RNA-seq, 16S rRNA gene sequencing and selective growth experiments by compositional data analysis
AD Fernandes, JN Reid, JM Macklaim, TA McMurrough, DR Edgell, ...
Microbiome 2, 1-13, 2014
9102014
Archaea and the origin(s) of DNA replication proteins
DR Edgell, WF Doolittle
Cell 89 (7), 995-998, 1997
3241997
Barriers to intron promiscuity in bacteria
DR Edgell, M Belfort, DA Shub
Journal of Bacteriology 182 (19), 5281-5289, 2000
1722000
An Expanded Plasmid-Based Genetic Toolbox Enables Cas9 Genome Editing and Stable Maintenance of Synthetic Pathways in Phaeodactylum tricornutum
SS Slattery, A Diamond, H Wang, JA Therrien, JT Lant, T Jazey, K Lee, ...
ACS synthetic biology 7 (2), 328-338, 2018
1342018
Tapping natural reservoirs of homing endonucleases for targeted gene modification
R Takeuchi, AR Lambert, ANS Mak, K Jacoby, RJ Dickson, GB Gloor, ...
Proceedings of the National Academy of Sciences 108 (32), 13077-13082, 2011
1162011
Bacterial group I introns: mobile RNA catalysts
G Hausner, M Hafez, DR Edgell
Mobile DNA 5, 1-12, 2014
982014
Efficient inter-species conjugative transfer of a CRISPR nuclease for targeted bacterial killing
TA Hamilton, GM Pellegrino, JA Therrien, DT Ham, PC Bartlett, BJ Karas, ...
Nature Communications 10 (1), 4544, 2019
882019
Learning to live together: mutualism between self-splicing introns and their hosts
DR Edgell, VR Chalamcharla, M Belfort
BMC biology 9, 1-9, 2011
882011
Mobile DNA elements in T4 and related phages
DR Edgell, EA Gibb, M Belfort
Virology journal 7, 1-15, 2010
882010
FhuD1, a ferric hydroxamate-binding lipoprotein in Staphylococcus aureus: a case of gene duplication and lateral transfer
MT Sebulsky, CD Speziali, BH Shilton, DR Edgell, DE Heinrichs
Journal of Biological Chemistry 279 (51), 53152-53159, 2004
862004
Gene duplications in evolution of archaeal family B DNA polymerases
DR Edgell, HP Klenk, WF Doolittle
Journal of bacteriology 179 (8), 2632-2640, 1997
841997
Genes within genes: multiple LAGLIDADG homing endonucleases target the ribosomal protein S3 gene encoded within an rnl group I intron of Ophiostoma and related taxa
J Sethuraman, A Majer, NC Friedrich, DR Edgell, G Hausner
Molecular biology and evolution 26 (10), 2299-2315, 2009
802009
mitoTev‐TALE: a monomeric DNA editing enzyme to reduce mutant mitochondrial DNA levels
CV Pereira, SR Bacman, T Arguello, U Zekonyte, SL Williams, DR Edgell, ...
EMBO molecular medicine 10 (9), e8084, 2018
702018
Repression of branched-chain amino acid synthesis in Staphylococcus aureus is mediated by isoleucine via CodY, and by a leucine-rich attenuator peptide
JC Kaiser, AN King, JC Grigg, JR Sheldon, DR Edgell, MEP Murphy, ...
PLoS genetics 14 (1), e1007159, 2018
672018
Monomeric site-specific nucleases for genome editing
BP Kleinstiver, JM Wolfs, T Kolaczyk, AK Roberts, SX Hu, DR Edgell
Proceedings of the National Academy of Sciences 109 (21), 8061-8066, 2012
652012
Selfish DNA: homing endonucleases find a home
DR Edgell
Current Biology 19 (3), R115-R117, 2009
642009
Related homing endonucleases I-BmoI and I-TevI use different strategies to cleave homologous recognition sites
DR Edgell, DA Shub
Proceedings of the National Academy of Sciences 98 (14), 7898-7903, 2001
592001
High incidence of significant urinary ascorbic acid concentrations in a west coast population—implications for routine urinalysis
ML Brigden, D Edgell, M McPherson, A Leadbeater, G Hoag
Clinical Chemistry 38 (3), 426-431, 1992
571992
Intron-encoded homing endonuclease I-TevI also functions as a transcriptional autorepressor
DR Edgell, V Derbyshire, PV Roey, S LaBonne, MJ Stanger, Z Li, ...
Nature structural & molecular biology 11 (10), 936-944, 2004
512004
SegG endonuclease promotes marker exclusion and mediates co-conversion from a distant cleavage site
Q Liu, A Belle, DA Shub, M Belfort, DR Edgell
Journal of molecular biology 334 (1), 13-23, 2003
512003
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