Dorothy D. Sears, Dorothy Sears Worrall
Dorothy D. Sears, Dorothy Sears Worrall
Arizona State University; Adjunct, UC San Diego
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Toll-like receptor 4–dependent and–independent cytokine secretion induced by minimally oxidized low-density lipoprotein in macrophages
YI Miller, S Viriyakosol, DS Worrall, A Boullier, S Butler, JL Witztum
Arteriosclerosis, thrombosis, and vascular biology 25 (6), 1213-1219, 2005
SirT1 regulates adipose tissue inflammation
MP Gillum, ME Kotas, DM Erion, R Kursawe, P Chatterjee, KT Nead, ...
Diabetes 60 (12), 3235-3245, 2011
PPARγ activation in adipocytes is sufficient for systemic insulin sensitization
S Sugii, P Olson, DD Sears, M Saberi, AR Atkins, GD Barish, SH Hong, ...
Proceedings of the National Academy of Sciences 106 (52), 22504-22509, 2009
Adipocyte NCoR knockout decreases PPARγ phosphorylation and enhances PPARγ activity and insulin sensitivity
P Li, WQ Fan, J Xu, M Lu, H Yamamoto, J Auwerx, DD Sears, S Talukdar, ...
Cell 147 (4), 815-826, 2011
Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice
P Li, M Lu, MTA Nguyen, EJ Bae, J Chapman, D Feng, M Hawkins, ...
Journal of biological chemistry 285 (20), 15333-15345, 2010
TLR4 and insulin resistance
JJ Kim, DD Sears
Gastroenterology research and practice 2010, 2010
Metabolic effects of intermittent fasting
RE Patterson, DD Sears
Annual review of nutrition 37, 2017
Fatty acid-induced insulin resistance: decreased muscle PI3K activation but unchanged Akt phosphorylation
YT Kruszynska, DS Worrall, J Ofrecio, JP Frias, G Macaraeg, JM Olefsky
The Journal of Clinical Endocrinology & Metabolism 87 (1), 226-234, 2002
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight
FE Garrett-Bakelman, M Darshi, SJ Green, RC Gur, L Lin, BR Macias, ...
Science 364 (6436), 2019
Intermittent fasting and human metabolic health
RE Patterson, GA Laughlin, AZ LaCroix, SJ Hartman, L Natarajan, ...
Journal of the Academy of Nutrition and Dietetics 115 (8), 1203-1212, 2015
Mechanisms of human insulin resistance and thiazolidinedione-mediated insulin sensitization
DD Sears, G Hsiao, A Hsiao, JG Yu, CH Courtney, JM Ofrecio, ...
Proceedings of the National Academy of Sciences 106 (44), 18745-18750, 2009
12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice
DD Sears, PD Miles, J Chapman, JM Ofrecio, F Almazan, D Thapar, ...
PLoS One 4 (9), e7250, 2009
FOXO1 transrepresses peroxisome proliferator-activated receptor γ transactivation, coordinating an insulin-induced feed-forward response in adipocytes
WQ Fan, T Imamura, N Sonoda, DD Sears, D Patsouris, JJ Kim, ...
Journal of Biological Chemistry 284 (18), 12188-12197, 2009
Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance
P Li, S Liu, M Lu, G Bandyopadhyay, D Oh, T Imamura, AMF Johnson, ...
Cell 167 (4), 973-984. e12, 2016
TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis
S Inokuchi-Shimizu, EJ Park, YS Roh, L Yang, B Zhang, J Song, S Liang, ...
The Journal of clinical investigation 124 (8), 3566-3578, 2014
Variance-modeled posterior inference of microarray data: detecting gene-expression changes in 3T3-L1 adipocytes
A Hsiao, DS Worrall, JM Olefsky, S Subramaniam
Bioinformatics 20 (17), 3108-3127, 2004
Insulin induces heterologous desensitization of G protein-coupled receptor and insulin-like growth factor I signaling by downregulating β-arrestin-1
S Dalle, T Imamura, DW Rose, DS Worrall, S Ugi, CJ Hupfeld, JM Olefsky
Molecular and cellular biology 22 (17), 6272-6285, 2002
The effects of intracellular calcium depletion on insulin signaling in 3T3-L1 adipocytes
DS Worrall, JM Olefsky
Molecular Endocrinology 16 (2), 378-389, 2002
MBX-102/JNJ39659100, a novel peroxisome proliferator-activated receptor-ligand with weak transactivation activity retains antidiabetic properties in the absence of weight gain …
FM Gregoire, F Zhang, HJ Clarke, TA Gustafson, DD Sears, S Favelyukis, ...
Molecular Endocrinology 23 (7), 975-988, 2009
Selective modulation of promoter recruitment and transcriptional activity of PPARγ
DD Sears, A Hsiao, JM Ofrecio, J Chapman, W He, JM Olefsky
Biochemical and biophysical research communications 364 (3), 515-521, 2007
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