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Hardik Shah
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MitoCarta3. 0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations
S Rath, R Sharma, R Gupta, T Ast, C Chan, TJ Durham, RP Goodman, ...
Nucleic Acids Research 49 (D1), D1541-D1547, 2021
8322021
Carcinoma–astrocyte gap junctions promote brain metastasis by cGAMP transfer
Q Chen, A Boire, X Jin, M Valiente, EE Er, A Lopez-Soto, L S. Jacob, ...
Nature 533 (7604), 493-498, 2016
8072016
Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation
LA Monticelli, MD Buck, AL Flamar, SA Saenz, ED Tait Wojno, ...
Nature immunology 17 (6), 656-665, 2016
2532016
L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH
AM Intlekofer, B Wang, H Liu, H Shah, C Carmona-Fontaine, ...
Nature chemical biology 13 (5), 494-500, 2017
2302017
SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication
Y Zhang, R Guo, SH Kim, H Shah, S Zhang, JH Liang, Y Fang, M Gentili, ...
Nature communications 12 (1), 1676, 2021
1282021
Hepatic NADH reductive stress underlies common variation in metabolic traits
RP Goodman, AL Markhard, H Shah, R Sharma, OS Skinner, CB Clish, ...
Nature 583 (7814), 122-126, 2020
1162020
A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering
TL To, AM Cuadros, H Shah, WHW Hung, Y Li, SH Kim, DHF Rubin, ...
Cell 179 (5), 1222-1238. e17, 2019
1162019
Loss of the RNA polymerase III repressor MAF1 confers obesity resistance
N Bonhoure, A Byrnes, RD Moir, W Hodroj, F Preitner, V Praz, G Marcelin, ...
Genes & development 29 (9), 934-947, 2015
1162015
Lipid deprivation induces a stable, naive-to-primed intermediate state of pluripotency in human PSCs
D Cornacchia, C Zhang, B Zimmer, SY Chung, Y Fan, MA Soliman, ...
Cell Stem Cell 25 (1), 120-136. e10, 2019
1082019
An engineered enzyme that targets circulating lactate to alleviate intracellular NADH: NAD+ imbalance
A Patgiri, OS Skinner, Y Miyazaki, G Schleifer, E Marutani, H Shah, ...
Nature biotechnology 38 (3), 309-313, 2020
982020
In Vivo Imaging of Glutamine Metabolism to the Oncometabolite 2-Hydroxyglutarate in IDH1/2 Mutant Tumors
L Salamanca-Cardona, H Shah, AJ Poot, FM Correa, V Di Gialleonardo, ...
Cell metabolism 26 (6), 830-841. e3, 2017
912017
Vitamin B6 addiction in acute myeloid leukemia
CC Chen, B Li, SE Millman, C Chen, X Li, JP Morris, A Mayle, YJ Ho, ...
Cancer Cell 37 (1), 71-84. e7, 2020
582020
Sarcosine Is Uniquely Modulated by Aging and Dietary Restriction in Rodents and Humans
RO Walters, E Arias, A Diaz, ES Burgos, F Guan, S Tiano, K Mao, ...
Cell Reports 25 (3), 663-676. e6, 2018
472018
Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS
AA Jourdain, BE Begg, E Mick, H Shah, SE Calvo, OS Skinner, R Sharma, ...
Molecular Cell 81 (9), 1905-1919. e12, 2021
392021
Combinatorial GxGxE CRISPR screen identifies SLC25A39 in mitochondrial glutathione transport linking iron homeostasis to OXPHOS
HS Xiaojian Shi, Bryn Reinstadler, Hardik Shah, Tsz-Leung To ,Katie Byrne ...
Nature Communications 13, 2022
342022
Hypoxia ameliorates brain hyperoxia and NAD+ deficiency in a murine model of Leigh syndrome
RMH Grange, R Sharma, H Shah, B Reinstadler, O Goldberger, ...
Molecular Genetics and Metabolism 133 (1), 83-93, 2021
182021
Correction: Corrigendum: Carcinoma–astrocyte gap junctions promote brain metastasis by cGAMP transfer
Q Chen, A Boire, X Jin, M Valiente, E Emrah Er, A Lopez-Soto, LS Jacob, ...
Nature 544 (7648), 124-124, 2017
132017
Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity
H Fan, S Xia, J Xiang, Y Li, MO Ross, SA Lim, F Yang, J Tu, L Xie, ...
Nature 623 (7989), 1034-1043, 2023
112023
Congenital Hypermetabolism and Uncoupled Oxidative Phosphorylation
RD Ganetzky, AL Markhard, I Yee, S Clever, A Cahill, H Shah, Z Grabarek, ...
New England Journal of Medicine 387 (15), 1395-1403, 2022
102022
Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis
JJA Saab, LN Dzierozynski, PB Jonker, R AminiTabrizi, H Shah, ...
Elife 12, e81289, 2023
92023
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