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Carcinoma–astrocyte gap junctions promote brain metastasis by cGAMP transfer Q Chen, A Boire, X Jin, M Valiente, EE Er, A Lopez-Soto, L S. Jacob, ... Nature 533 (7604), 493-498, 2016 | 807 | 2016 |
Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation LA Monticelli, MD Buck, AL Flamar, SA Saenz, ED Tait Wojno, ... Nature immunology 17 (6), 656-665, 2016 | 253 | 2016 |
L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH AM Intlekofer, B Wang, H Liu, H Shah, C Carmona-Fontaine, ... Nature chemical biology 13 (5), 494-500, 2017 | 230 | 2017 |
SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication Y Zhang, R Guo, SH Kim, H Shah, S Zhang, JH Liang, Y Fang, M Gentili, ... Nature communications 12 (1), 1676, 2021 | 128 | 2021 |
Hepatic NADH reductive stress underlies common variation in metabolic traits RP Goodman, AL Markhard, H Shah, R Sharma, OS Skinner, CB Clish, ... Nature 583 (7814), 122-126, 2020 | 116 | 2020 |
A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering TL To, AM Cuadros, H Shah, WHW Hung, Y Li, SH Kim, DHF Rubin, ... Cell 179 (5), 1222-1238. e17, 2019 | 116 | 2019 |
Loss of the RNA polymerase III repressor MAF1 confers obesity resistance N Bonhoure, A Byrnes, RD Moir, W Hodroj, F Preitner, V Praz, G Marcelin, ... Genes & development 29 (9), 934-947, 2015 | 116 | 2015 |
Lipid deprivation induces a stable, naive-to-primed intermediate state of pluripotency in human PSCs D Cornacchia, C Zhang, B Zimmer, SY Chung, Y Fan, MA Soliman, ... Cell Stem Cell 25 (1), 120-136. e10, 2019 | 108 | 2019 |
An engineered enzyme that targets circulating lactate to alleviate intracellular NADH: NAD+ imbalance A Patgiri, OS Skinner, Y Miyazaki, G Schleifer, E Marutani, H Shah, ... Nature biotechnology 38 (3), 309-313, 2020 | 98 | 2020 |
In Vivo Imaging of Glutamine Metabolism to the Oncometabolite 2-Hydroxyglutarate in IDH1/2 Mutant Tumors L Salamanca-Cardona, H Shah, AJ Poot, FM Correa, V Di Gialleonardo, ... Cell metabolism 26 (6), 830-841. e3, 2017 | 91 | 2017 |
Vitamin B6 addiction in acute myeloid leukemia CC Chen, B Li, SE Millman, C Chen, X Li, JP Morris, A Mayle, YJ Ho, ... Cancer Cell 37 (1), 71-84. e7, 2020 | 58 | 2020 |
Sarcosine Is Uniquely Modulated by Aging and Dietary Restriction in Rodents and Humans RO Walters, E Arias, A Diaz, ES Burgos, F Guan, S Tiano, K Mao, ... Cell Reports 25 (3), 663-676. e6, 2018 | 47 | 2018 |
Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS AA Jourdain, BE Begg, E Mick, H Shah, SE Calvo, OS Skinner, R Sharma, ... Molecular Cell 81 (9), 1905-1919. e12, 2021 | 39 | 2021 |
Combinatorial GxGxE CRISPR screen identifies SLC25A39 in mitochondrial glutathione transport linking iron homeostasis to OXPHOS HS Xiaojian Shi, Bryn Reinstadler, Hardik Shah, Tsz-Leung To ,Katie Byrne ... Nature Communications 13, 2022 | 34 | 2022 |
Hypoxia ameliorates brain hyperoxia and NAD+ deficiency in a murine model of Leigh syndrome RMH Grange, R Sharma, H Shah, B Reinstadler, O Goldberger, ... Molecular Genetics and Metabolism 133 (1), 83-93, 2021 | 18 | 2021 |
Correction: Corrigendum: Carcinoma–astrocyte gap junctions promote brain metastasis by cGAMP transfer Q Chen, A Boire, X Jin, M Valiente, E Emrah Er, A Lopez-Soto, LS Jacob, ... Nature 544 (7648), 124-124, 2017 | 13 | 2017 |
Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity H Fan, S Xia, J Xiang, Y Li, MO Ross, SA Lim, F Yang, J Tu, L Xie, ... Nature 623 (7989), 1034-1043, 2023 | 11 | 2023 |
Congenital Hypermetabolism and Uncoupled Oxidative Phosphorylation RD Ganetzky, AL Markhard, I Yee, S Clever, A Cahill, H Shah, Z Grabarek, ... New England Journal of Medicine 387 (15), 1395-1403, 2022 | 10 | 2022 |
Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis JJA Saab, LN Dzierozynski, PB Jonker, R AminiTabrizi, H Shah, ... Elife 12, e81289, 2023 | 9 | 2023 |