| Rational design of cationic lipids for siRNA delivery SC Semple, A Akinc, J Chen, AP Sandhu, BL Mui, CK Cho, DWY Sah, ... Nature biotechnology 28 (2), 172-176, 2010 | 1836 | 2010 |
| The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs A Akinc, MA Maier, M Manoharan, K Fitzgerald, M Jayaraman, S Barros, ... Nature nanotechnology 14 (12), 1084-1087, 2019 | 973 | 2019 |
| Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT P Dubreuil, S Letard, M Ciufolini, L Gros, M Humbert, N Castéran, L Borge, ... PloS one 4 (9), e7258, 2009 | 445 | 2009 |
| Oxidation of oximes to nitrile oxides with hypervalent iodine reagents BA Mendelsohn, S Lee, S Kim, F Teyssier, VS Aulakh, MA Ciufolini Organic Letters 11 (7), 1539-1542, 2009 | 250 | 2009 |
| Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells G Basha, TI Novobrantseva, N Rosin, YYC Tam, IM Hafez, MK Wong, ... Molecular Therapy 19 (12), 2186-2200, 2011 | 248 | 2011 |
| Chiral hypervalent iodine reagents in asymmetric reactions H Liang, MA Ciufolini Angewandte Chemie International Edition 50 (50), 11849-11851, 2011 | 197 | 2011 |
| Amino lipids and methods for the delivery of nucleic acids MJ Hope, SC Semple, J Chen, TD Madden, PR Cullis, MA Ciufolini, ... US Patent 9,139,554, 2015 | 171 | 2015 |
| Total synthesis of tricyclic azaspirane derivatives of tyrosine: FR901483 and TAN1251C M Ousmer, NA Braun, C Bavoux, M Perrin, MA Ciufolini Journal of the American Chemical Society 123 (31), 7534-7538, 2001 | 170 | 2001 |
| Lipid nanoparticle siRNA systems for silencing the androgen receptor in human prostate cancer in vivo JB Lee, K Zhang, YYC Tam, YK Tam, NM Belliveau, VYC Sung, PJC Lin, ... International Journal of Cancer 131 (5), E781-E790, 2012 | 161 | 2012 |
| Oxidative amidation of phenols through the use of hypervalent iodine reagents: Development and applications MA Ciufolini, NA Braun, S Canesi, M Ousmer, J Chang, D Chai Synthesis 2007 (24), 3759-3772, 2007 | 161 | 2007 |
| Reductive cleavage of TROC groups under neutral conditions with cadmium-lead couple Q Dong, CE Anderson, MA Ciufolini Tetrahedron letters 36 (32), 5681-5682, 1995 | 159 | 1995 |
| New oxidative transformations of phenolic and indolic oxazolines: an avenue to useful azaspirocyclic building blocks NA Braun, M Ousmer, JD Bray, D Bouchu, K Peters, EM Peters, ... The Journal of Organic Chemistry 65 (14), 4397-4408, 2000 | 158 | 2000 |
| Fully stereocontrolled total syntheses of (-)-cylindricine C and (-)-2-epicylindricine C: a departure in sulfonamide chemistry S Canesi, D Bouchu, MA Ciufolini Angewandte Chemie (International ed. in English) 43 (33), 4336-4338, 2004 | 151 | 2004 |
| Iterative Oxazole Assembly via α‐Chloroglycinates: Total Synthesis of (−)‐Muscoride A PY Coqueron, C Didier, MA Ciufolini Angewandte Chemie International Edition 42 (12), 1411-1414, 2003 | 119 | 2003 |
| Chemoenzymic synthesis of chiral furan derivatives: useful building blocks for optically active structures DG Drueckhammer, CF Barbas III, K Nozaki, CH Wong, CY Wood, ... The Journal of Organic Chemistry 53 (8), 1607-1611, 1988 | 115 | 1988 |
| Amino lipids and methods for the delivery of nucleic acids MJ Hope, SC Semple, J Chen, TD Madden, PR Cullis, MA Ciufolini, ... US Patent 10,653,780, 2020 | 105 | 2020 |
| A stereospecific route to aziridinomitosanes: The synthesis of novel mitomycin congeners S Danishefsky, EM Berman, M Ciufolini, SJ Etheredge, BE Segmuller Journal of the American Chemical Society 107 (13), 3891-3898, 1985 | 105 | 1985 |
| Synthesis of spirolactams from tyrosine amides and related substances NA Braun, MA Ciufolini, K Peters, EM Peter Tetrahedron letters 39 (26), 4667-4670, 1998 | 104 | 1998 |
| Development of a weak-base docetaxel derivative that can be loaded into lipid nanoparticles IV Zhigaltsev, G Winters, M Srinivasulu, J Crawford, M Wong, L Amankwa, ... Journal of Controlled Release 144 (3), 332-340, 2010 | 102 | 2010 |
| Influence of cationic lipid composition on uptake and intracellular processing of lipid nanoparticle formulations of siRNA PJC Lin, YYC Tam, I Hafez, A Sandhu, S Chen, MA Ciufolini, IR Nabi, ... Nanomedicine: Nanotechnology, Biology and Medicine 9 (2), 233-246, 2013 | 99 | 2013 |
