| Constitutive and regulated α-secretase cleavage of Alzheimer’s amyloid precursor protein by a disintegrin metalloprotease S Lammich, E Kojro, R Postina, S Gilbert, R Pfeiffer, M Jasionowski, ... Proceedings of the national academy of sciences 96 (7), 3922-3927, 1999 | 1641 | 1999 |
| A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model R Postina, A Schroeder, I Dewachter, J Bohl, U Schmitt, E Kojro, ... The Journal of clinical investigation 113 (10), 1456-1464, 2004 | 882 | 2004 |
| The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion C Hundhausen, D Misztela, TA Berkhout, N Broadway, P Saftig, K Reiss, ... Blood 102 (4), 1186-1195, 2003 | 799 | 2003 |
| Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins S Mechtersheimer, P Gutwein, N Agmon-Levin, A Stoeck, M Oleszewski, ... The Journal of cell biology 155 (4), 661-674, 2001 | 490 | 2001 |
| Receptor for advanced glycation end products is subjected to protein ectodomain shedding by metalloproteinases L Zhang, M Bukulin, E Kojro, A Roth, VV Metz, F Fahrenholz, PP Nawroth, ... Journal of Biological Chemistry 283 (51), 35507-35516, 2008 | 376 | 2008 |
| Regulation of the α‐secretase ADAM10 by its prodomain and proprotein convertases A Anders, S Gilbert, W Garten, R Postina, F Fahrenholz The FASEB Journal 15 (10), 1837-1839, 2001 | 341 | 2001 |
| Tumor necrosis factor‐α converting enzyme is processed by proprotein‐convertases to its mature form which is degraded upon phorbol ester stimulation K Endres, A Anders, E Kojro, S Gilbert, F Fahrenholz, R Postina European journal of biochemistry 270 (11), 2386-2393, 2003 | 175 | 2003 |
| A closer look at α-secretase R Postina Current Alzheimer Research 5 (2), 179-186, 2008 | 160 | 2008 |
| Genomic structure and functional characterization of the human ADAM10 promoter C Prinzen, U Müller, K Endres, F Fahrenholz, R Postina The FASEB Journal 19 (11), 1522-1524, 2005 | 160 | 2005 |
| The disintegrin ADAM9 indirectly contributes to the physiological processing of cellular prion by modulating ADAM10 activity MA Cisse, C Sunyach, S Lefranc-Jullien, R Postina, B Vincent, F Checler Journal of Biological Chemistry 280 (49), 40624-40631, 2005 | 156 | 2005 |
| Neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) slows down Alzheimer's disease-like pathology in amyloid precursor protein-transgenic mice D Rat, U Schmitt, F Tippmann, I Dewachter, C Theunis, E Wieczerzak, ... The FASEB Journal 25 (9), 3208, 2011 | 155 | 2011 |
| Separate agonist and peptide antagonist binding sites of the oxytocin receptor defined by their transfer into the V2 vasopressin receptor R Postina, E Kojro, F Fahrenholz Journal of Biological Chemistry 271 (49), 31593-31601, 1996 | 150 | 1996 |
| The neuropeptide PACAP promotes?‐secretase pathway for processing Alzheimer amyloid precursor protein E Kojro, R Postina, C Buro, C Meiringer, K Gehrig‐Burger, F Fahrenholz The FASEB journal 20 (3), 512-514, 2006 | 146 | 2006 |
| Activation of α‐secretase cleavage R Postina Journal of neurochemistry 120, 46-54, 2012 | 131 | 2012 |
| α‐Secretase activity of the disintegrin metalloprotease ADAM 10: influences of domain structure F Fahrenholz, S Gilbert, E Kojro, S Lammich, R Postina Annals of the New York Academy of Sciences 920 (1), 215-222, 2000 | 125 | 2000 |
| The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10 T Jefferson, U Auf dem Keller, C Bellac, VV Metz, C Broder, J Hedrich, ... Cellular and Molecular Life Sciences 70, 309-333, 2013 | 117 | 2013 |
| Unfolded protein response signaling by transcription factor XBP‐1 regulates ADAM10 and is affected in Alzheimer's disease S Reinhardt, F Schuck, S Grösgen, M Riemenschneider, T Hartmann, ... The FASEB Journal 28 (2), 978-997, 2014 | 113 | 2014 |
| Shedding of the amyloid precursor protein‐like protein APLP2 by disintegrin‐metalloproteinases: Retinoic acid‐induced upregulation of substrate and proteinase ADAM10 during … K Endres, R Postina, A Schroeder, U Mueller, F Fahrenholz The FEBS journal 272 (22), 5808-5820, 2005 | 107 | 2005 |
| Melatonin stimulates the nonamyloidogenic processing of βAPP through the positive transcriptional regulation of ADAM10 and ADAM17 M Shukla, HH Htoo, P Wintachai, JF Hernandez, C Dubois, R Postina, ... Journal of pineal research 58 (2), 151-165, 2015 | 91 | 2015 |
| α-secretase activation–an approach to Alzheimer’s disease therapy F Fahrenholz, R Postina Neurodegenerative Diseases 3 (4-5), 255-261, 2006 | 80 | 2006 |
