Daniel Coombs

Cited by

	All	Since 2018
Citations	3944	1886
h-index	37	25
i10-index	64	52

460

230

115

345

200220032004200520062007200820092010201120122013201420152016201720182019202020212022202312 26 30 52 66 77 99 102 158 154 181 210 172 222 225 224 248 303 335 439 455 99

Public access

View all

37 articles

3 articles

available

not available

Based on funding mandates

Co-authors

MA IrvineBC Centre for Disease ControlVerified email at bccdc.ca
Byron GoldsteinLaboratory Fellow, Theoretical Biology and Biophysics Group, Los Alamos National LaboratoryVerified email at lanl.gov
Omer DushekProfessor, University of OxfordVerified email at path.ox.ac.uk
Raibatak DasPrincipal scientist at Applied BioMath, LLCVerified email at cornell.edu
Michael A. GilchristAssociate Professor, University of Tennessee, KnoxvilleVerified email at utk.edu
Michael OtterstatterBritish Columbia Centre for Disease ControlVerified email at bccdc.ca
Mark GilbertAssociate Professor, University of British ColumbiaVerified email at bccdc.ca
Rebeca Cardim FalcãoPostdoctoral Researcher at BCCDCVerified email at bccdc.ca
Philip Anton van der MerweProfessor of Molecular Immunology, University of OxfordVerified email at path.ox.ac.uk
Sarafa Adewale IyaniwuraPhD Candidate, Department of Mathematics, University of British Columbia, VancouverVerified email at aims.ac.za
Caroline ColijnSimon Fraser University, Department of MathematicsVerified email at sfu.ca
Michael R. GoldMicrobiology and Immunology, University of British ColumbiaVerified email at mail.ubc.ca
Robert BalshawCentre for Healthcare Innovation, University of ManitobaVerified email at umanitoba.ca
Alan S PerelsonSenior Fellow, Los Alamos National LaboratoryVerified email at lanl.gov
Naveed Zafar JanjuaBritish Columbia Centre for Disease Control & University of British ColumbiaVerified email at bccdc.ca
Bernhard KonradUBC VancouverVerified email at math.ubc.ca
Guy TanentzapfThe University of British ColumbiaVerified email at mail.ubc.ca
Jessica E StockdaleAssistant Professor, Simon Fraser UniversityVerified email at sfu.ca
Sean C. AndersonFisheries and Oceans CanadaVerified email at dfo-mpo.gc.ca
Nicola MulberryPhD student, Simon Fraser UniversityVerified email at sfu.ca

Daniel Coombs

Professor, Mathematics, University of British Columbia

Verified email at math.ubc.ca - Homepage

theoretical immunology virus dynamics cell biophysics epidemiology


Title Sort by citations Sort by year Sort by title	Cited by Cited by	Year
Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time M Aleksic, O Dushek, H Zhang, E Shenderov, JL Chen, V Cerundolo, ... Immunity 32 (2), 163-174, 2010	270	2010
T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell PA González, LJ Carreño, D Coombs, JE Mora, E Palmieri, B Goldstein, ... Proceedings of the National Academy of Sciences 102 (13), 4824-4829, 2005	164	2005
An age-structured model of HIV infection that allows for variations in the production rate of viral particles and the death rate of productively infected cells PW Nelson, MA Gilchrist, D Coombs, JM Hyman, AS Perelson Math. Biosci. Eng 1 (2), 267-288, 2004	162	2004
Activated TCRs remain marked for internalization after dissociation from pMHC D Coombs, AM Kalergis, SG Nathenson, C Wofsy, B Goldstein Nature immunology 3 (10), 926-931, 2002	161	2002
Evolution of virulence: interdependence, constraints, and selection using nested models MA Gilchrist, D Coombs Theoretical population biology 69 (2), 145-153, 2006	150	2006
Evaluating the importance of within-and between-host selection pressures on the evolution of chronic pathogens D Coombs, MA Gilchrist, CL Ball Theoretical population biology 72 (4), 576-591, 2007	146	2007
A hidden Markov model for single particle tracks quantifies dynamic interactions between LFA-1 and the actin cytoskeleton R Das, CW Cairo, D Coombs PLoS computational biology 5 (11), e1000556, 2009	139	2009
The influence of transport on the kinetics of binding to surface receptors: application to cells and BIAcore B Goldstein, D Coombs, X He, AR Pineda, C Wofsy Journal of molecular recognition 12 (5), 293-299, 1999	132	1999
Modelling the combined impact of interventions in averting deaths during a synthetic‐opioid overdose epidemic MA Irvine, M Kuo, JA Buxton, R Balshaw, M Otterstatter, L Macdougall, ... Addiction 114 (9), 1602-1613, 2019	130	2019
Diffusion on a sphere with localized traps: Mean first passage time, eigenvalue asymptotics, and Fekete points D Coombs, R Straube, M Ward SIAM Journal on Applied Mathematics 70 (1), 302-332, 2009	115	2009
Optimizing within-host viral fitness: infected cell lifespan and virion production rate MA Gilchrist, D Coombs, AS Perelson Journal of theoretical biology 229 (2), 281-288, 2004	106	2004
Equilibrium thermodynamics of cell-cell adhesion mediated by multiple ligand-receptor pairs D Coombs, M Dembo, C Wofsy, B Goldstein Biophysical journal 86 (3), 1408-1423, 2004	104	2004
Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor SA Freeman, V Jaumouillé, K Choi, BE Hsu, HS Wong, L Abraham, ... Nature communications 6 (1), 6168, 2015	98	2015
A stochastic model of latently infected cell reactivation and viral blip generation in treated HIV patients JM Conway, D Coombs PLoS computational biology 7 (4), e1002033, 2011	91	2011
A role for rebinding in rapid and reliable T cell responses to antigen O Dushek, R Das, D Coombs PLoS computational biology 5 (11), e1000578, 2009	90	2009
Quantifying the impact of COVID-19 control measures using a Bayesian model of physical distancing SC Anderson, AM Edwards, M Yerlanov, N Mulberry, JE Stockdale, ... PLoS computational biology 16 (12), e1008274, 2020	89	2020
Distribution of take-home opioid antagonist kits during a synthetic opioid epidemic in British Columbia, Canada: a modelling study MA Irvine, JA Buxton, M Otterstatter, R Balshaw, R Gustafson, M Tyndall, ... The Lancet Public Health 3 (5), e218-e225, 2018	88	2018
Calculations show substantial serial engagement of T cell receptors C Wofsy, D Coombs, B Goldstein Biophysical journal 80 (2), 606-612, 2001	84	2001
Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation O Dushek, M Aleksic, RJ Wheeler, H Zhang, SP Cordoba, YC Peng, ... Science signaling 4 (176), ra39-ra39, 2011	81	2011
Mechanical force regulates integrin turnover in Drosophila in vivo M Pines, R Das, SJ Ellis, A Morin, S Czerniecki, L Yuan, M Klose, ... Nature cell biology 14 (9), 935-943, 2012	77	2012

The system can't perform the operation now. Try again later.

Articles 1–20

Citations per year

Duplicate citations

Merged citations

Add co-authorsCo-authors

Follow

Cited by

Co-authors