Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML A Chaturvedi, MM Araujo Cruz, N Jyotsana, A Sharma, H Yun, K Görlich, ... Blood, The Journal of the American Society of Hematology 122 (16), 2877-2887, 2013 | 241 | 2013 |
The role of cystine/glutamate antiporter SLC7A11/xCT in the pathophysiology of cancer N Jyotsana, KT Ta, KE DelGiorno Frontiers in Oncology 12, 858462, 2022 | 82 | 2022 |
Lipid nanoparticle-mediated siRNA delivery for safe targeting of human CML in vivo N Jyotsana, A Sharma, A Chaturvedi, R Budida, M Scherr, F Kuchenbauer, ... Annals of hematology 98, 1905-1918, 2019 | 71 | 2019 |
Enantiomer-specific and paracrine leukemogenicity of mutant IDH metabolite 2-hydroxyglutarate A Chaturvedi, MM Araujo Cruz, N Jyotsana, A Sharma, R Goparaju, ... Leukemia 30 (8), 1708-1715, 2016 | 57 | 2016 |
Minimal dosing of leukocyte targeting TRAIL decreases triple-negative breast cancer metastasis following tumor resection N Jyotsana, Z Zhang, LE Himmel, F Yu, MR King Science Advances 5 (7), eaaw4197, 2019 | 55 | 2019 |
The Impact of COVID-19 on Cancer Risk and Treatment N Jyotsana, MR King Cellular and Molecular Bioengineering, 2020 | 49 | 2020 |
Single-cell transcriptomics reveals a conserved metaplasia program in pancreatic injury Z Ma, NK Lytle, B Chen, N Jyotsana, SW Novak, CJ Cho, L Caplan, ... Gastroenterology 162 (2), 604-620. e20, 2022 | 46 | 2022 |
Constitutive IRF8 expression inhibits AML by activation of repressed immune response signaling A Sharma, H Yun, N Jyotsana, A Chaturvedi, A Schwarzer, E Yung, ... Leukemia 29 (1), 157-168, 2015 | 42 | 2015 |
Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in Acute Myeloid Leukemia S Mohanty, N Jyotsana, A Sharma, A Kloos, R Gabdoulline, B Othman, ... Cancers 12 (10), 2766, 2020 | 32 | 2020 |
Impact of MLL5 expression on decitabine efficacy and DNA methylation in acute myeloid leukemia H Yun, F Damm, D Yap, A Schwarzer, A Chaturvedi, N Jyotsana, ... haematologica 99 (9), 1456, 2014 | 30 | 2014 |
Exploiting differential RNA splicing patterns: a potential new group of therapeutic targets in cancer N Jyotsana, M Heuser Expert opinion on therapeutic targets 22 (2), 107-121, 2018 | 25 | 2018 |
Fibulin-6 regulates pro-fibrotic TGF-β responses in neonatal mouse ventricular cardiac fibroblasts A Chowdhury, L Hasselbach, F Echtermeyer, N Jyotsana, G Theilmeier, ... Scientific Reports 7 (1), 42725, 2017 | 19 | 2017 |
Pyrimethamine as a potent and selective inhibitor of acute myeloid leukemia identified by high-throughput drug screening A Sharma, N Jyotsana, C K Lai, A Chaturvedi, R Gabdoulline, K Görlich, ... Current Cancer Drug Targets 16 (9), 818-828, 2016 | 19 | 2016 |
RNA interference efficiently targets human leukemia driven by a fusion oncogene in vivo N Jyotsana, A Sharma, A Chaturvedi, M Scherr, F Kuchenbauer, L Sajti, ... Leukemia 32 (1), 224-226, 2018 | 17 | 2018 |
Effective drug treatment identified by in vivo screening in a transplantable patient-derived xenograft model of chronic myelomonocytic leukemia A Kloos, K Mintzas, L Winckler, R Gabdoulline, Y Alwie, N Jyotsana, ... Leukemia 34 (11), 2951-2963, 2020 | 15 | 2020 |
Nanoparticle-mediated Targeting of the Fusion Gene RUNX1/ETO in t(8;21)-positive Acute Myeloid Leukaemia OH Hasan Issa, Laura Swart, Milad Rasouli, Minoo Ashtiani, Sirintra Nakjang ... bioRxiv, 508893, 2022 | 13* | 2022 |
Fabrication and characterization of tumor nano-lysate as a preventative vaccine for breast cancer JA Dombroski, N Jyotsana, DW Crews, Z Zhang, MR King Langmuir 36 (23), 6531-6539, 2020 | 12 | 2020 |
A novel inhibitor of mutant IDH1 induces differentiation in vivo and prolongs survival in a mouse model of leukemia A Chaturvedi, MMA Cruz, R Goparaju, N Jyotsana, H Baehre, K Goerlich, ... Blood 124 (21), 3598, 2014 | 11 | 2014 |
Overcoming TRAIL-resistance by sensitizing prostate cancer 3D spheroids with taxanes MRK Korie A. Grayson, Nidhi Jyotsana, Nerymar Ortiz-Otero PLOS ONE 16 (3), 2021 | 10 | 2021 |
Meningioma 1 is indispensable for mixed lineage leukemia-rearranged acute myeloid leukemia A Sharma, N Jyotsana, R Gabdoulline, D Heckl, F Kuchenbauer, ... Haematologica 105 (5), 1294, 2020 | 10 | 2020 |