New isoflavonoid glycosides and related constituents from astragali radix (Astragalus membranaceus) and their inhibitory activity on nitric oxide production LJ Zhang, HK Liu, PC Hsiao, LMY Kuo, IJ Lee, TS Wu, WF Chiou, YH Kuo Journal of agricultural and food chemistry 59 (4), 1131-1137, 2011 | 111 | 2011 |
Fructus Corni suppresses hepatic gluconeogenesis related gene transcription, enhances glucose responsiveness of pancreatic beta-cells, and prevents toxin induced beta-cell death CC Chen, CY Hsu, CY Chen, HK Liu Journal of Ethnopharmacology 117 (3), 483-490, 2008 | 95 | 2008 |
Astragalus membranaceus-Polysaccharides Ameliorates Obesity, Hepatic Steatosis, Neuroinflammation and Cognition Impairment without Affecting Amyloid … YC Huang, HJ Tsay, MK Lu, CH Lin, CW Yeh, HK Liu, YJ Shiao International journal of molecular sciences 18 (12), 2746, 2017 | 91 | 2017 |
Evaluation of the potential hypoglycemic and Beta-cell protective constituents isolated from Corni fructus to tackle insulin-dependent diabetes mellitus MH Lin, HK Liu, WJ Huang, CC Huang, TH Wu, FL Hsu Journal of agricultural and food chemistry 59 (14), 7743-7751, 2011 | 80 | 2011 |
Abnormal protein expression in the corpus cavernosum impairs erectile function in type 2 diabetes WF Chiou, HK Liu, CW Juan BJU international 105 (5), 674-680, 2010 | 49 | 2010 |
A novel regulation of IRS1 (insulin receptor substrate-1) expression following short term insulin administration AJ Ruiz-Alcaraz, HK Liu, DJ Cuthbertson, EJ Mcmanus, S Akhtar, ... Biochemical Journal 392 (2), 345-352, 2005 | 49 | 2005 |
Honeysuckle (Lonicera japonica) and Huangqi (Astragalus membranaceus) Suppress SARS-CoV-2 Entry and COVID-19 Related Cytokine Storm in Vitro YC Yeh, LH Doan, ZY Huang, LW Chu, TH Shi, YR Lee, CT Wu, CH Lin, ... Frontiers in pharmacology 12, 765553, 2022 | 44 | 2022 |
The novel anti-hyperglycemic effect of Paeoniae radix via the transcriptional suppression of phosphoenopyruvate carboxykinase (PEPCK) YC Juan, WJ Tsai, YL Lin, GJ Wang, JJ Cheng, HY Yang, CY Hsu, HK Liu Phytomedicine 17 (8-9), 626-634, 2010 | 43 | 2010 |
Impaired cognition and cerebral glucose regulation are associated with astrocyte activation in the parenchyma of metabolically stressed APPswe/PS1dE9 mice CW Yeh, SHH Yeh, FS Shie, WS Lai, HK Liu, TT Tzeng, HJ Tsay, ... Neurobiology of aging 36 (11), 2984-2994, 2015 | 38 | 2015 |
A high-sucrose diet aggravates Alzheimer's disease pathology, attenuates hypothalamic leptin signaling, and impairs food-anticipatory activity in APPswe/PS1dE9 mice SHH Yeh, FS Shie, HK Liu, HH Yao, PC Kao, YH Lee, LM Chen, SM Hsu, ... Neurobiology of Aging 90, 60-74, 2020 | 37 | 2020 |
Delayed intervention with a novel SGLT2 inhibitor NGI001 suppresses diet‐induced metabolic dysfunction and non‐alcoholic fatty liver disease in mice H Chiang, JC Lee, HC Huang, H Huang, HK Liu, C Huang British Journal of Pharmacology 177 (2), 239-253, 2020 | 37 | 2020 |
Augmented insulin and leptin resistance of high fat diet-fed APPswe/PS1dE9 transgenic mice exacerbate obesity and glycemic dysregulation YH Lee, HC Hsu, PC Kao, YJ Shiao, SHH Yeh, FS Shie, SM Hsu, CW Yeh, ... International Journal of Molecular Sciences 19 (8), 2333, 2018 | 35 | 2018 |
Lanostane-triterpenoids from the fungus Phellinus gilvus HK Liu, TH Tsai, TT Chang, CJ Chou, LC Lin Phytochemistry 70 (4), 558-563, 2009 | 35 | 2009 |
Administration of a decoction of sucrose-and polysaccharide-rich radix astragali (huang qi) ameliorated insulin resistance and Fatty liver but affected Beta-cell function in … YC Juan, YH Kuo, CC Chang, LJ Zhang, YY Lin, CY Hsu, HK Liu Evidence-Based Complementary and Alternative Medicine 2011, 2011 | 34 | 2011 |
Functional characterisation of the regulation of CAAT enhancer binding protein alpha by GSK-3 phosphorylation of Threonines 222/226 HK Liu, S Perrier, C Lipina, D Finlay, H McLauchlan, CJ Hastie, ... BMC Molecular Biology 7, 1-12, 2006 | 33 | 2006 |
The ethyl acetate fraction of corn silk exhibits dual antioxidant and anti-glycation activities and protects insulin-secreting cells from glucotoxicity CC Chang, W Yuan, HY Roan, JL Chang, HC Huang, YC Lee, HJ Tsay, ... BMC complementary and alternative medicine 16, 1-11, 2016 | 29 | 2016 |
N-acetyl-GLP-1: a DPP IV-resistant analogue of glucagon-like peptide-1 (GLP-1) with improved effects on pancreatic β-cell-associated gene expression HK Liu, BD Green, VA Gault, JT McCluskey, NH McClenaghan, ... Cell biology international 28 (1), 69-73, 2004 | 29 | 2004 |
Pharmacological evaluation of insulin mimetic novel suppressors of PEPCK gene transcription from Paeoniae Rubra Radix YC Juan, CC Chang, WJ Tsai, YL Lin, YS Hsu, HK Liu Journal of ethnopharmacology 137 (1), 592-600, 2011 | 28 | 2011 |
Epigallocatechin gallate inhibits hepatitis B virus infection in human liver chimeric mice YH Lai, CP Sun, HC Huang, JC Chen, HK Liu, C Huang BMC complementary and alternative medicine 18, 1-7, 2018 | 27 | 2018 |
Xuefu Zhuyu decoction ameliorates obesity, hepatic steatosis, neuroinflammation, amyloid deposition and cognition impairment in metabolically stressed APPswe/PS1dE9 mice CW Yeh, HK Liu, LC Lin, KT Liou, YC Huang, CH Lin, TT Tzeng, FS Shie, ... Journal of ethnopharmacology 209, 50-61, 2017 | 26 | 2017 |