|An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and i NKT cells|
WY Lee, TJ Moriarty, CHY Wong, H Zhou, RM Strieter, N Van Rooijen, ...
Nature immunology 11 (4), 295-302, 2010
|Real-time high resolution 3D imaging of the lyme disease spirochete adhering to and escaping from the vasculature of a living host|
TJ Moriarty, MU Norman, P Colarusso, T Bankhead, P Kubes, ...
PLoS Pathog 4 (6), e1000090, 2008
|Functional multimerization of human telomerase requires an RNA interaction domain in the N terminus of the catalytic subunit|
TJ Moriarty, S Huard, S Dupuis, C Autexier
Molecular and cellular biology 22 (4), 1253-1265, 2002
|Functional organization of repeat addition processivity and DNA synthesis determinants in the human telomerase multimer|
TJ Moriarty, DT Marie-Egyptienne, C Autexier
Molecular and cellular biology 24 (9), 3720-3733, 2004
|Molecular mechanisms involved in vascular interactions of the Lyme disease pathogen in a living host|
MU Norman, TJ Moriarty, AR Dresser, B Millen, P Kubes, G Chaconas
PLoS Pathog 4 (10), e1000169, 2008
|The C terminus of the human telomerase reverse transcriptase is a determinant of enzyme processivity|
S Huard, TJ Moriarty, C Autexier
Nucleic acids research 31 (14), 4059-4070, 2003
|An Anchor Site–Type Defect in Human Telomerase That Disrupts Telomere Length Maintenance and Cellular Immortalization|
TJ Moriarty, RJ Ward, MAS Taboski, C Autexier
Molecular biology of the cell 16 (7), 3152-3161, 2005
|Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules|
TJ Moriarty, M Shi, YP Lin, R Ebady, H Zhou, T Odisho, PO Hardy, ...
Molecular microbiology 86 (5), 1116-1131, 2012
|Telomerase can act as a template-and RNA-independent terminal transferase|
NF Lue, D Bosoy, TJ Moriarty, C Autexier, B Altman, S Leng
Proceedings of the National Academy of Sciences 102 (28), 9778-9783, 2005
|Interactions between the discoidin domain receptor 1 and β1 integrin regulate attachment to collagen|
LA Staudinger, SJ Spano, W Lee, N Coelho, D Rajshankar, MP Bendeck, ...
Biology open 2 (11), 1148-1159, 2013
|Invariant natural killer T cells act as an extravascular cytotoxic barrier for joint-invading Lyme Borrelia|
WY Lee, MJ Sanz, CHY Wong, PO Hardy, A Salman-Dilgimen, TJ Moriarty, ...
Proceedings of the National Academy of Sciences 111 (38), 13936-13941, 2014
|Characterization and in vitro reaction properties of 19 unique hairpin telomeres from the linear plasmids of the Lyme disease spirochete|
Y Tourand, J Deneke, TJ Moriarty, G Chaconas
Journal of Biological Chemistry 284 (11), 7264-7272, 2009
|Rapid upregulation of telomerase activity in human leukemia HL-60 cells treated with clinical doses of the DNA-damaging drug etoposide|
TJ Moriarty, S Dupuis, C Autexier
Leukemia 16 (6), 1112-1120, 2002
|Biomechanics of Borrelia burgdorferi Vascular Interactions|
R Ebady, AF Niddam, AE Boczula, YR Kim, N Gupta, TT Tang, T Odisho, ...
Cell reports 16 (10), 2593-2604, 2016
|Regulation of 5′ template usage and incorporation of noncognate nucleotides by human telomerase|
TJ MORIARTY, DT MARIE-EGYPTIENNE, C AUTEXIER
Rna 11 (9), 1448-1460, 2005
|Evolutionary aspects of emerging Lyme disease in Canada|
NH Ogden, EJ Feil, PA Leighton, LR Lindsay, G Margos, S Mechai, ...
Applied and environmental microbiology 81 (21), 7350-7359, 2015
|Plasma fibronectin stabilizes Borrelia burgdorferi–endothelial interactions under vascular shear stress by a catch-bond mechanism|
AF Niddam, R Ebady, A Bansal, A Koehler, B Hinz, TJ Moriarty
Proceedings of the National Academy of Sciences 114 (17), E3490-E3498, 2017
|The Structure of Treponema pallidum Tp0751 (Pallilysin) Reveals a Non-canonical Lipocalin Fold that Mediates Adhesion to Extracellular Matrix Components and Interactions with …|
ML Parker, S Houston, H Pětrošová, KV Lithgow, R Hof, C Wetherell, ...
PLOS Pathogens 12 (9), e1005919, 2016
|Identification of the determinant conferring permissive substrate usage in the telomere resolvase, ResT|
TJ Moriarty, G Chaconas
Journal of Biological Chemistry 284 (35), 23293-23301, 2009
|Identification of Tp0751 (pallilysin) as a Treponema pallidum vascular adhesin by heterologous expression in the Lyme disease spirochete|
WCA Kao, H Pětrošová, R Ebady, KV Lithgow, P Rojas, Y Zhang, YE Kim, ...
Scientific reports 7 (1), 1-13, 2017