| Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor γ agonist N Nicolakakis, T Aboulkassim, B Ongali, C Lecrux, P Fernandes, ... Journal of Neuroscience 28 (37), 9287-9296, 2008 | 305 | 2008 |
| The neurovascular unit in brain function and disease C Lecrux, E Hamel Acta physiologica 203 (1), 47-59, 2011 | 298 | 2011 |
| [18F]FDG PET signal is driven by astroglial glutamate transport RNP Zimmer Eduardo R, Parent Maxime J, Souza Débora G, Leuzy Antoine, Lecrux ... Nature Neuroscience, 2017 | 194 | 2017 |
| Caspase-1 inhibition alleviates cognitive impairment and neuropathology in an Alzheimer’s disease mouse model J Flores, A Noël, B Foveau, J Lynham, C Lecrux, AC LeBlanc Nature communications 9 (1), 3916, 2018 | 180 | 2018 |
| Age-dependent rescue by simvastatin of Alzheimer's disease cerebrovascular and memory deficits XK Tong, C Lecrux, E Hamel Journal of neuroscience 32 (14), 4705-4715, 2012 | 158 | 2012 |
| Pyramidal neurons are “neurogenic hubs” in the neurovascular coupling response to whisker stimulation C Lecrux, X Toussay, A Kocharyan, P Fernandes, S Neupane, ... Journal of Neuroscience 31 (27), 9836-9847, 2011 | 157 | 2011 |
| Angiotensin II type 1 receptor blocker losartan prevents and rescues cerebrovascular, neuropathological and cognitive deficits in an Alzheimer’s disease model B Ongali, N Nicolakakis, XK Tong, T Aboulkassim, P Papadopoulos, ... Neurobiology of disease 68, 126-136, 2014 | 136 | 2014 |
| COX-2-derived prostaglandin E2 produced by pyramidal neurons contributes to neurovascular coupling in the rodent cerebral cortex A Lacroix, X Toussay, E Anenberg, C Lecrux, N Ferreirós, A Karagiannis, ... Journal of Neuroscience 35 (34), 11791-11810, 2015 | 97 | 2015 |
| Neuronal networks and mediators of cortical neurovascular coupling responses in normal and altered brain states C Lecrux, E Hamel PHILOSOPHICAL TRANSACTIONS B, 2016 | 95 | 2016 |
| Transgenic mice overexpressing APP and transforming growth factor-β1 feature cognitive and vascular hallmarks of Alzheimer's disease B Ongali, N Nicolakakis, C Lecrux, T Aboulkassim, P Rosa-Neto, ... The American journal of pathology 177 (6), 3071-3080, 2010 | 59 | 2010 |
| Impact of altered cholinergic tones on the neurovascular coupling response to whisker stimulation C Lecrux, CH Sandoe, S Neupane, P Kropf, X Toussay, XK Tong, ... The Journal of Neuroscience, 2017 | 57 | 2017 |
| Effects of magnesium treatment in a model of internal capsule lesion in spontaneously hypertensive rats C Lecrux, C McCabe, CJ Weir, L Gallagher, J Mullin, O Touzani, KW Muir, ... Stroke 39 (2), 448-454, 2008 | 54 | 2008 |
| Pyramidal cells and cytochrome P450 epoxygenase products in the neurovascular coupling response to basal forebrain cholinergic input C Lecrux, A Kocharyan, CH Sandoe, XK Tong, E Hamel Journal of Cerebral Blood Flow & Metabolism 32 (5), 896-906, 2012 | 34 | 2012 |
| How reliable is cerebral blood flow to map changes in neuronal activity? C Lecrux, M Bourourou, E Hamel Autonomic Neuroscience 217, 71-79, 2019 | 33 | 2019 |
| Spontaneously hypertensive rats are highly vulnerable to AMPA-induced brain lesions C Lecrux, O Nicole, L Chazalviel, C Catone, J Chuquet, ET MacKenzie, ... Stroke 38 (11), 3007-3015, 2007 | 25 | 2007 |
| Caspase vinyl sulfone small molecule inhibitors prevent axonal degeneration in human neurons and reverse cognitive impairment in Caspase-6-overexpressing mice P Pakavathkumar, A Noël, C Lecrux, A Tubeleviciute-Aydin, E Hamel, ... Mol Neurodegener 12 (1), 22, 2017 | 21 | 2017 |
| Transforming growth factor-β1 induces cerebrovascular dysfunction and astrogliosis through angiotensin II type 1 receptor-mediated signaling pathways B Ongali, N Nicolakakis, XK Tong, C Lecrux, H Imboden, E Hamel Canadian journal of physiology and pharmacology 96 (5), 527-534, 2018 | 19 | 2018 |
| Effects of urotensin-II on cerebral blood flow and ischemia in anesthetized rats J Chuquet, C Lecrux, D Chatenet, J Leprince, L Chazalviel, S Roussel, ... Experimental neurology 210 (2), 577-584, 2008 | 13 | 2008 |
| A functional cerebral endothelium is necessary to protect against cognitive decline LJ Trigiani, M Bourourou, M Lacalle-Aurioles, C Lecrux, A Hynes, ... Journal of Cerebral Blood Flow & Metabolism 42 (1), 74-89, 2022 | 6 | 2022 |
| Alzheimer's disease and cerebrovascular pathology alter inward rectifier potassium (KIR2.1) channels in endothelium of mouse cerebral arteries M Lacalle‐Aurioles, LJ Trigiani, M Bourourou, C Lecrux, E Hamel British Journal of Pharmacology 179 (10), 2259-2274, 2022 | 5 | 2022 |
Edith HamelProfessor, McGill UniversityVerified email at mcgill.ca
