DNA-demethylating agents target colorectal cancer cells by inducing viral mimicry by endogenous transcripts D Roulois, HL Yau, R Singhania, Y Wang, A Danesh, SY Shen, H Han, ... Cell 162 (5), 961-973, 2015 | 1259 | 2015 |
DNA hypermethylation within TERT promoter upregulates TERT expression in cancer DD Lee, R Leao, M Komosa, M Gallo, CH Zhang, T Lipman, M Remke, ... The Journal of clinical investigation 129 (1), 223-229, 2019 | 182 | 2019 |
Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates O Kis, R Kaedbey, S Chow, A Danesh, M Dowar, T Li, Z Li, J Liu, ... Nature communications 8 (1), 15086, 2017 | 138 | 2017 |
The genomic landscape of schwannoma S Agnihotri, S Jalali, MR Wilson, A Danesh, M Li, G Klironomos, ... Nature genetics 48 (11), 1339-1348, 2016 | 134 | 2016 |
Therapeutic radiation for childhood cancer drives structural aberrations of NF2 in meningiomas S Agnihotri, S Suppiah, PD Tonge, S Jalali, A Danesh, JP Bruce, ... Nature communications 8 (1), 186, 2017 | 89 | 2017 |
Activating mutations affecting the Dbl homology domain of SOS2 cause Noonan syndrome V Cordeddu, JC Yin, C Gunnarsson, C Virtanen, S Drunat, F Lepri, ... Human mutation 36 (11), 1080-1087, 2015 | 87 | 2015 |
Landscape of genomic alterations in high-grade serous ovarian cancer from exceptional long-and short-term survivors SYC Yang, S Lheureux, K Karakasis, JV Burnier, JP Bruce, DL Clouthier, ... Genome medicine 10, 1-17, 2018 | 82 | 2018 |
Phase I/II trial of the combination of 177lutetium prostate specific membrane antigen 617 and idronoxil (NOX66) in men with end-stage metastatic castration-resistant prostate … M Crumbaker, S Pathmanandavel, AO Yam, A Nguyen, B Ho, L Chan, ... European urology oncology 4 (6), 963-970, 2021 | 30 | 2021 |
Centromeric cohesion failure invokes a conserved choreography of chromosomal mis-segregations in pancreatic neuroendocrine tumor R Quevedo, A Spreafico, J Bruce, A Danesh, S El Ghamrasni, A Giesler, ... Genome Medicine 12, 1-15, 2020 | 12 | 2020 |
Heterogeneous alteration of the ERBB3–MYC axis associated with MEK inhibitor resistance in a KRAS-mutated low-grade serous ovarian cancer patient I Colombo, S Garg, A Danesh, J Bruce, P Shaw, Q Tan, R Quevedo, ... Molecular Case Studies 5 (6), a004341, 2019 | 7 | 2019 |
Early Cancer Detection in Li–Fraumeni Syndrome with Cell-Free DNA D Wong, P Luo, LE Oldfield, H Gong, L Brunga, R Rabinowicz, V Subasri, ... Cancer Discovery 14 (1), 104-119, 2024 | 6 | 2024 |
Identifying mechanisms of resistance by circulating tumor DNA in EVOLVE, a phase II trial of cediranib plus olaparib for ovarian cancer at time of PARP inhibitor progression S Lheureux, SD Prokopec, LE Oldfield, E Gonzalez-Ochoa, JP Bruce, ... Clinical Cancer Research 29 (18), 3706-3716, 2023 | 5 | 2023 |
Myeloma immunoglobulin rearrangement and translocation detection through targeted capture sequencing S Chow, O Kis, DT Mulder, A Danesh, J Bruce, TT Wang, D Reece, ... Life Science Alliance 6 (1), 2023 | 5 | 2023 |
Clinical significance of clonal hematopoiesis in the setting of autologous stem cell transplantation for lymphoma T Lackraj, S Ben Barouch, JJF Medeiros, S Pedersen, A Danesh, ... American Journal of Hematology 97 (12), 1538-1547, 2022 | 5 | 2022 |
Noninvasive diagnosis of actionable mutations by deep sequencing of circulating cell free DNA (cfDNA) in multiple myeloma (MM) R Kaedbey, O Kis, A Danesh, M Dowar, T Li, ZH Li, J Liu, M Mansour, ... Clinical Lymphoma, Myeloma and Leukemia 15, e45-e46, 2015 | 5 | 2015 |
Multimodal immunogenomic biomarker analysis of tumors from pediatric patients enrolled to a phase 1-2 study of single-agent atezolizumab A Nabbi, A Danesh, O Espin-Garcia, S Pedersen, J Wellum, LH Fu, ... Nature Cancer 4 (4), 502-515, 2023 | 4 | 2023 |
Integrated, longitudinal analysis of cell-free DNA in uveal melanoma D Wong, P Luo, N Znassi, DP Arteaga, D Gray, A Danesh, M Han, ... Cancer Research Communications 3 (2), 267-280, 2023 | 4 | 2023 |
Germline pathogenic variants in neuroblastoma patients are enriched in BARD1 and predict worse survival J Kim, Z Vaksman, LE Egolf, R Kaufman, JP Evans, KL Conkrite, ... JNCI: Journal of the National Cancer Institute 116 (1), 149-159, 2024 | 3 | 2024 |
Germline pathogenic variants in 786 neuroblastoma patients J Kim, Z Vaksman, LE Egolf, R Kaufman, JP Evans, KL Conkrite, ... medRxiv, 2023 | 3 | 2023 |
Integrated analysis of cell-free DNA for the early detection of cancer in people with Li-Fraumeni Syndrome D Wong, P Luo, L Oldfield, H Gong, L Brunga, R Rabinowicz, V Subasri, ... medRxiv, 2022.10. 07.22280848, 2022 | 3 | 2022 |