| Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation M Watanabe, SM Houten, C Mataki, MA Christoffolete, BW Kim, H Sato, ... Nature 439 (7075), 484-489, 2006 | 2352 | 2006 |
| Mechanism of action of fibrates on lipid and lipoprotein metabolism B Staels, J Dallongeville, J Auwerx, K Schoonjans, E Leitersdorf, ... Circulation 98 (19), 2088-2093, 1998 | 2100 | 1998 |
| TGR5-mediated bile acid sensing controls glucose homeostasis C Thomas, A Gioiello, L Noriega, A Strehle, J Oury, G Rizzo, ... Cell metabolism 10 (3), 167-177, 2009 | 1875 | 2009 |
| Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors TT Lu, M Makishima, JJ Repa, K Schoonjans, TA Kerr, J Auwerx, ... Molecular cell 6 (3), 507-515, 2000 | 1690 | 2000 |
| The organization, promoter analysis, and expression of the human PPARγ gene L Fajas, D Auboeuf, E Raspé, K Schoonjans, AM Lefebvre, R Saladin, ... Journal of Biological Chemistry 272 (30), 18779-18789, 1997 | 1655 | 1997 |
| Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression K Schoonjans, B Staels, J Auwerx Journal of lipid research 37 (5), 907-925, 1996 | 1618 | 1996 |
| PPARalpha and PPARgamma activators direct a distinct tissue‐specific transcriptional response via a PPRE in the lipoprotein lipase gene. K Schoonjans, J Peinado‐Onsurbe, AM Lefebvre, RA Heyman, M Briggs, ... The EMBO journal 15 (19), 5336-5348, 1996 | 1527 | 1996 |
| Targeting bile-acid signalling for metabolic diseases C Thomas, R Pellicciari, M Pruzanski, J Auwerx, K Schoonjans Nature reviews Drug discovery 7 (8), 678-693, 2008 | 1421 | 2008 |
| The peroxisome proliferator activated receptors (PPARS) and their effects on lipid metabolism and adipocyte differentiation K Schoonjans, B Staels, J Auwerx Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism 1302 (2), 93-109, 1996 | 1381 | 1996 |
| The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity C Cantó, RH Houtkooper, E Pirinen, DY Youn, MH Oosterveer, Y Cen, ... Cell metabolism 15 (6), 838-847, 2012 | 1207 | 2012 |
| The NAD+/sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling L Mouchiroud, RH Houtkooper, N Moullan, E Katsyuba, D Ryu, C Cantó, ... Cell 154 (2), 430-441, 2013 | 1170 | 2013 |
| NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice H Zhang, D Ryu, Y Wu, K Gariani, X Wang, P Luan, D D’Amico, ... Science 352 (6292), 1436-1443, 2016 | 1094 | 2016 |
| PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation P Bai, C Cantó, H Oudart, A Brunyánszki, Y Cen, C Thomas, H Yamamoto, ... Cell metabolism 13 (4), 461-468, 2011 | 867 | 2011 |
| Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance S Fang, JM Suh, SM Reilly, E Yu, O Osborn, D Lackey, E Yoshihara, ... Nature medicine 21 (2), 159-165, 2015 | 733 | 2015 |
| Coordinate regulation of the expression of the fatty acid transport protein and acyl-CoA synthetase genes by PPARα and PPARγ activators G Martin, K Schoonjans, AM Lefebvre, B Staels, J Auwerx Journal of Biological Chemistry 272 (45), 28210-28217, 1997 | 708 | 1997 |
| Peroxisome proliterator-activated receptors, orphans with ligands and functions K Schoonjans, G Martin, B Staels, J Auwerx Current opinion in lipidology 8 (3), 159-166, 1997 | 653 | 1997 |
| Sirtuin functions in health and disease H Yamamoto, K Schoonjans, J Auwerx Molecular endocrinology 21 (8), 1745-1755, 2007 | 598 | 2007 |
| Attenuation of colon inflammation through activators of the retinoid X receptor (Rxr)/Peroxisome proliferator–activated receptor Γ (Pparγ) heterodimer: A basis for new … P Desreumaux, L Dubuquoy, S Nutten, M Peuchmaur, W Englaro, ... The Journal of experimental medicine 193 (7), 827-838, 2001 | 577 | 2001 |
| Regulation of peroxisome proliferator-activated receptor γ expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1 … L Fajas, K Schoonjans, L Gelman, JB Kim, J Najib, G Martin, JC Fruchart, ... Molecular and cellular biology 19 (8), 5495-5503, 1999 | 563 | 1999 |
| TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading TWH Pols, M Nomura, T Harach, GL Sasso, MH Oosterveer, C Thomas, ... Cell metabolism 14 (6), 747-757, 2011 | 554 | 2011 |
