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Howard T J Mount
Howard T J Mount
Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto
Verified email at utoronto.ca
Title
Cited by
Cited by
Year
Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
C Janus, J Pearson, JA McLaurin, PM Mathews, Y Jiang, SD Schmidt, ...
Nature 408 (6815), 979-982, 2000
20232000
Therapeutically effective antibodies against amyloid-β peptide target amyloid-β residues 4–10 and inhibit cytotoxicity and fibrillogenesis
J McLaurin, R Cecal, ME Kierstead, X Tian, AL Phinney, M Manea, ...
Nature medicine 8 (11), 1263-1269, 2002
5672002
Interactions between β-amyloid and central cholinergic neurons: implications for Alzheimer’s disease
S Kar, SPM Slowikowski, D Westaway, HTJ Mount
Journal of Psychiatry and Neuroscience 29 (6), 427-441, 2004
4902004
Cyclohexanehexol inhibitors of Aβ aggregation prevent and reverse Alzheimer phenotype in a mouse model
JA McLaurin, ME Kierstead, ME Brown, CA Hawkes, MHL Lambermon, ...
Nature medicine 12 (7), 801-808, 2006
4522006
Brain-derived neurotrophic factor rapidly enhances phosphorylation of the postsynaptic N-methyl-d-aspartate receptor subunit 1
PC Suen, K Wu, ES Levine, HTJ Mount, JL Xu, SY Lin, IB Black
Proceedings of the National Academy of Sciences 94 (15), 8191-8195, 1997
3731997
BDNF acutely increases tyrosine phosphorylation of the NMDA receptor subunit 2B in cortical and hippocampal postsynaptic densities
SY Lin, K Wu, ES Levine, HTJ Mount, PC Suen, IB Black
Molecular brain research 55 (1), 20-27, 1998
3391998
α5GABAA receptors mediate the amnestic but not sedative-hypnotic effects of the general anesthetic etomidate
VY Cheng, LJ Martin, EM Elliott, JH Kim, HTJ Mount, FA Taverna, ...
Journal of Neuroscience 26 (14), 3713-3720, 2006
2932006
Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of β-catenin, a component of the presenilin protein complex
M Nishimura, G Yu, G Levesque, DM Zhang, L Ruel, F Chen, P Milman, ...
Nature medicine 5 (2), 164-169, 1999
2761999
Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease
S Peng, DJ Garzon, M Marchese, W Klein, SD Ginsberg, BM Francis, ...
Journal of Neuroscience 29 (29), 9321-9329, 2009
2452009
Glial cell line-derived neurotrophic factor promotes the survival and morphologic differentiation of Purkinje cells.
HTJ Mount, DO Dean, J Alberch, CF Dreyfus, IB Black
Proceedings of the National Academy of Sciences 92 (20), 9092-9096, 1995
2211995
Glial cell line-derived neurotrophic factor promotes the survival and morphologic differentiation of Purkinje cells.
HTJ Mount, DO Dean, J Alberch, CF Dreyfus, IB Black
Proceedings of the National Academy of Sciences 92 (20), 9092-9096, 1995
2211995
APH-1 interacts with mature and immature forms of presenilins and nicastrin and may play a role in maturation of presenilin· nicastrin complexes
Y Gu, F Chen, N Sanjo, T Kawarai, H Hasegawa, M Duthie, W Li, X Ruan, ...
Journal of Biological Chemistry 278 (9), 7374-7380, 2003
2122003
Mature Glycosylation and Trafficking of Nicastrin Modulate Its Binding to Presenilins* 210
DS Yang, A Tandon, F Chen, G Yu, H Yu, S Arawaka, H Hasegawa, ...
Journal of Biological Chemistry 277 (31), 28135-28142, 2002
2072002
Unesterified docosahexaenoic acid is protective in neuroinflammation
SK Orr, S Palumbo, F Bosetti, HT Mount, JX Kang, CE Greenwood, ...
Journal of neurochemistry 127 (3), 378-393, 2013
1782013
The CNS glycoprotein Shadoo has PrPC‐like protective properties and displays reduced levels in prion infections
JC Watts, B Drisaldi, V Ng, J Yang, B Strome, P Horne, MS Sy, L Yoong, ...
The EMBO journal 26 (17), 4038-4050, 2007
1732007
Reduced fear and aggression and altered serotonin metabolism in Gtf2ird1‐targeted mice
EJ Young, T Lipina, E Tam, A Mandel, SJ Clapcote, AR Bechard, ...
Genes, Brain and Behavior 7 (2), 224-234, 2008
1662008
Inflammatory biomarkers in Alzheimer's disease plasma
AR Morgan, S Touchard, C Leckey, C O'Hagan, AJ Nevado-Holgado, ...
Alzheimer's & dementia 15 (6), 776-787, 2019
1402019
Presenilin 1 mutations activate γ42-secretase but reciprocally inhibit ε-secretase cleavage of amyloid precursor protein (APP) and S3-cleavage of notch
F Chen, YJ Gu, H Hasegawa, X Ruan, S Arawaka, P Fraser, D Westaway, ...
Journal of Biological Chemistry 277 (39), 36521-36526, 2002
1382002
Functional trkB neurotrophin receptors are intrinsic components of the adult brain postsynaptic density
K Wu, J Xu, P Suen, E Levine, Y Huang, HTJ Mount, S Lin, IB Black
Molecular brain research 43 (1-2), 286-290, 1996
1351996
Object recognition memory and BDNF expression are reduced in young TgCRND8 mice
BM Francis, J Kim, ME Barakat, S Fraenkl, YH Yücel, S Peng, B Michalski, ...
Neurobiology of aging 33 (3), 555-563, 2012
1292012
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