| A survey of current trends in computational drug repositioning J Li, S Zheng, B Chen, AJ Butte, SJ Swamidass, Z Lu Briefings in bioinformatics 17 (1), 2-12, 2016 | 299 | 2016 |
| Chem2Bio2RDF: a semantic framework for linking and data mining chemogenomic and systems chemical biology data B Chen, X Dong, D Jiao, H Wang, Q Zhu, Y Ding, D Wild BMC bioinformatics 11 (1), 255, 2010 | 220 | 2010 |
| Gaining insight into off-target mediated effects of drug candidates with a comprehensive systems chemical biology analysis J Scheiber, B Chen, M Milik, SCK Sukuru, A Bender, D Mikhailov, ... Journal of chemical information and modeling 49 (2), 308-317, 2009 | 169 | 2009 |
| PubChem as a source of polypharmacology B Chen, D Wild, R Guha Journal of chemical information and modeling 49 (9), 2044-2055, 2009 | 149 | 2009 |
| Assessing Drug Target Association using Semantic Linked Data B Chen, Y Ding, DJ Wild PLoS Computational Biology 8 (7), e1002574, 2012 | 142 | 2012 |
| Leveraging big data to transform target selection and drug discovery B Chen, AJ Butte Clinical Pharmacology & Therapeutics 99 (3), 285-297, 2016 | 124 | 2016 |
| The ChEMBL database as linked open data EL Willighagen, A Waagmeester, O Spjuth, P Ansell, AJ Williams, ... Journal of cheminformatics 5 (1), 1-12, 2013 | 101 | 2013 |
| Reversal of cancer gene expression correlates with drug efficacy and reveals therapeutic targets B Chen, L Ma, H Paik, M Sirota, W Wei, MS Chua, S So, AJ Butte Nature communications 8 (1), 1-12, 2017 | 76 | 2017 |
| Predicting drug target interactions using meta-path-based semantic network analysis G Fu, Y Ding, A Seal, B Chen, Y Sun, E Bolton BMC bioinformatics 17 (1), 160, 2016 | 73 | 2016 |
| Comparison of random forest and Pipeline Pilot Naive Bayes in prospective QSAR predictions. B Chen, RP Sheridan, V Hornak, JH Voigt Journal of Chemical Information and Modeling, 2012 | 70 | 2012 |
| Relating genes to function: identifying enriched transcription factors using the ENCODE ChIP-Seq significance tool RK Auerbach, B Chen, AJ Butte Bioinformatics 29 (15), 1922-1924, 2013 | 69 | 2013 |
| Relating hepatocellular carcinoma tumor samples and cell lines using gene expression data in translational research B Chen, M Sirota, H Fan-Minogue, D Hadley, AJ Butte BMC medical genomics 8 (S2), S5, 2015 | 56 | 2015 |
| Characteristics of drug combination therapy in oncology by analyzing clinical trial data on ClinicalTrials. gov M Wu, M Sirota, AJ Butte, BIN Chen Pacific Symposium on Biocomputing Co-Chairs, 68-79, 2014 | 49 | 2014 |
| Relating chemical structure to cellular response: an integrative analysis of gene expression, bioactivity, and structural data across 11,000 compounds B Chen, P Greenside, H Paik, M Sirota, D Hadley, AJ Butte CPT: pharmacometrics & systems pharmacology 4 (10), 576-584, 2015 | 44 | 2015 |
| PubChem BioAssays as a data source for predictive models B Chen, DJ Wild Journal of Molecular Graphics and Modelling 28 (5), 420-426, 2010 | 44 | 2010 |
| Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice S Zhang, X Song, D Cao, Z Xu, B Fan, L Che, J Hu, B Chen, M Dong, ... Journal of hepatology 67 (6), 1194-1203, 2017 | 40 | 2017 |
| Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell … B Chen, W Wei, L Ma, B Yang, RM Gill, MS Chua, AJ Butte, S So Gastroenterology 152 (8), 2022-2036, 2017 | 38 | 2017 |
| Mining Relational Paths in Integrated Biomedical Data B He, J Tang, Y Ding, H Wang, Y Sun, JH Shin, B Chen, G Moorthy, J Qiu, ... PLoS ONE 6 (12), e27506, 2011 | 31 | 2011 |
| Network medicine in disease analysis and therapeutics B Chen, AJ Butte Clinical Pharmacology & Therapeutics 94 (6), 627-629, 2013 | 30 | 2013 |
| Improving integrative searching of systems chemical biology data using semantic B Chen, Y Ding, DJ Wild Journal of cheminformatics 4, 6, 2012 | 26 | 2012 |
Atul J. ButteDirector, Bakar Computational Health Sciences Institute, University of California, San FranciscoVerified email at ucsf.edu
