| Design of amidobenzimidazole STING receptor agonists with systemic activity JM Ramanjulu, GS Pesiridis, J Yang, N Concha, R Singhaus, SY Zhang, ... Nature 564 (7736), 439-443, 2018 | 563 | 2018 |
| A DNA hypomethylation signature predicts antitumor activity of LSD1 inhibitors in SCLC HP Mohammad, KN Smitheman, CD Kamat, D Soong, KE Federowicz, ... Cancer cell 28 (1), 57-69, 2015 | 488 | 2015 |
| Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells J Billiard, JB Dennison, J Briand, RS Annan, D Chai, M Colón, ... Cancer & metabolism 1, 1-17, 2013 | 211 | 2013 |
| A simple assay for detection of small-molecule redox activity LA Lor, J Schneck, DE Mcnulty, E Diaz, M Brandt, SH Thrall, B Schwartz Journal of biomolecular screening 12 (6), 881-890, 2007 | 82 | 2007 |
| Discovery of novel cyanamide-based inhibitors of cathepsin C D Laine, M Palovich, B McCleland, E Petitjean, I Delhom, H Xie, J Deng, ... ACS medicinal chemistry letters 2 (2), 142-147, 2011 | 77 | 2011 |
| Identification of PDE4B Over 4D subtype-selective inhibitors revealing an unprecedented binding mode M Kranz, M Wall, B Evans, A Miah, S Ballantine, C Delves, B Dombroski, ... Bioorganic & medicinal chemistry 17 (14), 5336-5341, 2009 | 70 | 2009 |
| Inhibitors of LexA autoproteolysis and the bacterial SOS response discovered by an academic–industry partnership CY Mo, MJ Culyba, T Selwood, JM Kubiak, ZM Hostetler, AJ Jurewicz, ... ACS infectious diseases 4 (3), 349-359, 2017 | 54 | 2017 |
| Transition state for the NSD2-catalyzed methylation of histone H3 lysine 36 MB Poulin, JL Schneck, RE Matico, PJ McDevitt, MJ Huddleston, W Hou, ... Proceedings of the National Academy of Sciences 113 (5), 1197-1201, 2016 | 53 | 2016 |
| GSK356278, a potent, selective, brain-penetrant phosphodiesterase 4 inhibitor that demonstrates anxiolytic and cognition-enhancing effects without inducing side effects in … AR Rutter, A Poffe, P Cavallini, TG Davis, J Schneck, M Negri, E Vicentini, ... Journal of Pharmacology and Experimental Therapeutics 350 (1), 153-163, 2014 | 49 | 2014 |
| Genetic diversity of Flavobacterium columnare isolated from fish collected from warm and cold water. JL Schneck, LF Caslake Journal of Fish Diseases 29 (4), 2006 | 45 | 2006 |
| Chemical mechanism of a cysteine protease, cathepsin C, as revealed by integration of both steady-state and pre-steady-state solvent kinetic isotope effects JL Schneck, JP Villa, P McDevitt, MS McQueney, SH Thrall, TD Meek Biochemistry 47 (33), 8697-8710, 2008 | 44 | 2008 |
| Discovery and characterization of a class of pyrazole inhibitors of bacterial undecaprenyl pyrophosphate synthase N Concha, J Huang, X Bai, A Benowitz, P Brady, LSC Grady, LH Kryn, ... Journal of Medicinal Chemistry 59 (15), 7299-7304, 2016 | 37 | 2016 |
| Inhibition of LSD1 as a therapeutic strategy for the treatment of acute myeloid leukemia RG Kruger, H Mohammad, K Smitheman, M Cusan, Y Liu, M Pappalardi, ... Blood, The Journal of the American Society of Hematology 122 (21), 3964-3964, 2013 | 35 | 2013 |
| Targeting the regulatory site of ER aminopeptidase 1 leads to the discovery of a natural product modulator of antigen presentation J Liddle, JP Hutchinson, S Kitchen, P Rowland, M Neu, T Cecconie, ... Journal of Medicinal Chemistry 63 (6), 3348-3358, 2020 | 24 | 2020 |
| The amino-acid substituents of dipeptide substrates of cathepsin C can determine the rate-limiting steps of catalysis JK Rubach, G Cui, JL Schneck, AN Taylor, B Zhao, A Smallwood, ... Biochemistry 51 (38), 7551-7568, 2012 | 22 | 2012 |
| Growth of Biomphalaria glabrata (NMRI strain) and Helisoma trivolvis (Colorado strain) under laboratory conditions JL Schneck, B Fried American Malacological Bulletin 20 (1-2), 71-73, 2005 | 18 | 2005 |
| Effects of tonicity, digestive enzymes and bile salts, and nutrient media on the survival of excysted metacercariae of Echinostoma caproni B Fried, JL Schneck, EL Ponder Parasitology research 93, 1-4, 2004 | 18 | 2004 |
| Nucleosome binding alters the substrate bonding environment of histone H3 lysine 36 methyltransferase NSD2 MB Poulin, JL Schneck, RE Matico, W Hou, PJ McDevitt, M Holbert, ... Journal of the American Chemical Society 138 (21), 6699-6702, 2016 | 14 | 2016 |
| A highly selective, cell-permeable furin inhibitor BOS-318 rescues key features of cystic fibrosis airway disease LEJ Douglas, JA Reihill, MWY Ho, JM Axten, N Campobasso, JL Schneck, ... Cell Chemical Biology 29 (6), 947-957. e8, 2022 | 13 | 2022 |
| Preclinical characterization of GSK532, a novel STING agonist with potent anti-tumor activity J Yang, M Adam, J Clemens, K Creech, J Schneck, K Pasikanti, JL Tran, ... Cancer Research 78 (13_Supplement), 5554-5554, 2018 | 13 | 2018 |
