Mansoor Husain
Mansoor Husain
Ted Rogers Centre for Heart Research, Toronto General Hospital Research Institute, U of Toronto
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Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor–dependent and–independent pathways
K Ban, MH Noyan-Ashraf, J Hoefer, SS Bolz, DJ Drucker, M Husain
Circulation 117 (18), 2340-2350, 2008
Local proliferation dominates lesional macrophage accumulation in atherosclerosis
CS Robbins, I Hilgendorf, GF Weber, I Theurl, Y Iwamoto, JL Figueiredo, ...
Nature medicine 19 (9), 1166-1172, 2013
Sodium glucose cotransporter 2 inhibitors in the treatment of diabetes mellitus: cardiovascular and kidney effects, potential mechanisms, and clinical applications
HJL Heerspink, BA Perkins, DH Fitchett, M Husain, DZI Cherney
Circulation 134 (10), 752-772, 2016
Oral semaglutide and cardiovascular outcomes in patients with type 2 diabetes
M Husain, AL Birkenfeld, M Donsmark, K Dungan, FG Eliaschewitz, ...
New England Journal of Medicine 381 (9), 841-851, 2019
GLP-1R agonist liraglutide activates cytoprotective pathways and improves outcomes after experimental myocardial infarction in mice
MH Noyan-Ashraf, MA Momen, K Ban, AM Sadi, YQ Zhou, AM Riazi, ...
Diabetes 58 (4), 975-983, 2009
Control of human embryonic stem cell colony and aggregate size heterogeneity influences differentiation trajectories
CL Bauwens, R Peerani, S Niebruegge, KA Woodhouse, E Kumacheva, ...
Stem cells 26 (9), 2300-2310, 2008
Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death
IN Mungrue, R Gros, X You, A Pirani, A Azad, T Csont, R Schulz, J Butany, ...
The Journal of clinical investigation 109 (6), 735-743, 2002
A role for endoglin in coupling eNOS activity and regulating vascular tone revealed in hereditary hemorrhagic telangiectasia
M Toporsian, R Gros, MG Kabir, S Vera, K Govindaraju, DH Eidelman, ...
Circulation research 96 (6), 684-692, 2005
Genetic deletion or pharmacological inhibition of dipeptidyl peptidase-4 improves cardiovascular outcomes after myocardial infarction in mice
M Sauvé, K Ban, MA Momen, YQ Zhou, RM Henkelman, M Husain, ...
Diabetes 59 (4), 1063-1073, 2010
Autologous porcine heart cell transplantation improved heart function after a myocardial infarction
RK Li, RD Weisel, DAG Mickle, ZQ Jia, EJ Kim, T Sakai, S Tomita, ...
The Journal of thoracic and cardiovascular surgery 119 (1), 62-68, 2000
Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction
SA Dick, JA Macklin, S Nejat, A Momen, X Clemente-Casares, ...
Nature immunology 20 (1), 29-39, 2019
The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient
DL Costantini, EP Arruda, P Agarwal, KH Kim, Y Zhu, W Zhu, M Lebel, ...
Cell 123 (2), 347-358, 2005
Cardiac function in mice lacking the glucagon-like peptide-1 receptor
R Gros, X You, LL Baggio, MG Kabir, AM Sadi, IN Mungrue, TG Parker, ...
Endocrinology 144 (6), 2242-2252, 2003
Generation of human embryonic stem cell‐derived mesoderm and cardiac cells using size‐specified aggregates in an oxygen‐controlled bioreactor
S Niebruegge, CL Bauwens, R Peerani, N Thavandiran, S Masse, ...
Biotechnology and bioengineering 102 (2), 493-507, 2009
Self-renewing resident arterial macrophages arise from embryonic CX3CR1+ precursors and circulating monocytes immediately after birth
S Ensan, A Li, R Besla, N Degousee, J Cosme, M Roufaiel, EA Shikatani, ...
Nature immunology 17 (2), 159-168, 2016
Glucagon-like peptide (GLP)-1 (9-36) amide-mediated cytoprotection is blocked by exendin (9-39) yet does not require the known GLP-1 receptor
K Ban, KH Kim, CK Cho, M Sauve, EP Diamandis, PH Backx, DJ Drucker, ...
Endocrinology 151 (4), 1520-1531, 2010
From molecules to mammals: what's NOS got to do with it?
IN Mungrue, DS Bredt, DJ Stewart, M Husain
Acta Physiologica Scandinavica 179 (2), 123-135, 2003
Conditional cardiac overexpression of endothelin-1 induces inflammation and dilated cardiomyopathy in mice
LL Yang, R Gros, MG Kabir, A Sadi, AI Gotlieb, M Husain, DJ Stewart
Circulation 109 (2), 255-261, 2004
A glucagon-like peptide-1 analog reverses the molecular pathology and cardiac dysfunction of a mouse model of obesity
MH Noyan-Ashraf, EA Shikatani, I Schuiki, I Mukovozov, J Wu, RK Li, ...
Circulation 127 (1), 74-85, 2013
Myeloid differentiation factor-88 plays a crucial role in the pathogenesis of coxsackievirus B3–induced myocarditis and influences type I interferon production
K Fuse, G Chan, Y Liu, P Gudgeon, M Husain, M Chen, WC Yeh, S Akira, ...
Circulation 112 (15), 2276-2285, 2005
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