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Gao Zhang, Ph.D.
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Year
Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response
G Chen, AC Huang, W Zhang, G Zhang, M Wu, W Xu, Z Yu, J Yang, ...
Nature 560 (7718), 382-386, 2018
19972018
A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade
L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ...
Cell 175 (4), 984-997. e24, 2018
9882018
Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma
N Auslander, G Zhang, JS Lee, DT Frederick, B Miao, T Moll, T Tian, ...
Nature medicine 24 (10), 1545-1549, 2018
5362018
Enhancing CD8+ T cell fatty acid catabolism within a metabolically challenging tumor microenvironment increases the efficacy of melanoma immunotherapy
Y Zhang, R Kurupati, L Liu, XY Zhou, G Zhang, A Hudaihed, F Filisio, ...
Cancer cell 32 (3), 377-391. e9, 2017
4412017
Targeting ER stress–induced autophagy overcomes BRAF inhibitor resistance in melanoma
XH Ma, SF Piao, S Dey, Q Mcafee, G Karakousis, J Villanueva, LS Hart, ...
The Journal of clinical investigation 124 (3), 1406-1417, 2014
4392014
Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids
RW Jenkins, AR Aref, PH Lizotte, E Ivanova, S Stinson, CW Zhou, ...
Cancer discovery 8 (2), 196-215, 2018
4212018
Suppression of nucleotide metabolism underlies the establishment and maintenance of oncogene-induced senescence
KM Aird, G Zhang, H Li, Z Tu, BG Bitler, A Garipov, H Wu, Z Wei, ...
Cell reports 3 (4), 1252-1265, 2013
2812013
B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma
J Griss, W Bauer, C Wagner, M Simon, M Chen, ...
Nature communications 10 (1), 4186, 2019
2692019
Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors
G Zhang, DT Frederick, L Wu, Z Wei, C Krepler, S Srinivasan, YC Chae, ...
The Journal of clinical investigation 126 (5), 1834-1856, 2016
2542016
Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses
I Caņadas, R Thummalapalli, JW Kim, S Kitajima, RW Jenkins, ...
Nature medicine 24 (8), 1143-1150, 2018
2362018
PPT1 promotes tumor growth and is the molecular target of chloroquine derivatives in cancer
VW Rebecca, MC Nicastri, C Fennelly, CI Chude, JS Barber-Rotenberg, ...
Cancer discovery 9 (2), 220-229, 2019
1782019
A unified approach to targeting the lysosome's degradative and growth signaling roles
VW Rebecca, MC Nicastri, N McLaughlin, C Fennelly, Q McAfee, ...
Cancer discovery 7 (11), 1266-1283, 2017
1602017
PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas
H Lu, S Liu, G Zhang, B Wu, Y Zhu, DT Frederick, Y Hu, W Zhong, ...
Nature 550 (7674), 133-136, 2017
1602017
Identification of secreted proteins that reflect autophagy dynamics within tumor cells
AA Kraya, S Piao, X Xu, G Zhang, M Herlyn, P Gimotty, B Levine, ...
Autophagy 11 (1), 60-74, 2015
1552015
A stress-induced early innate response causes multidrug tolerance in melanoma
D Ravindran Menon, S Das, C Krepler, A Vultur, B Rinner, S Schauer, ...
Oncogene 34 (34), 4448-4459, 2015
1322015
A comprehensive patient-derived xenograft collection representing the heterogeneity of melanoma
C Krepler, K Sproesser, P Brafford, M Beqiri, B Garman, M Xiao, ...
Cell reports 21 (7), 1953-1967, 2017
1302017
BRAF inhibition stimulates melanoma-associated macrophages to drive tumor growth
T Wang, M Xiao, Y Ge, C Krepler, E Belser, A Lopez-Coral, X Xu, G Zhang, ...
Clinical cancer research 21 (7), 1652-1664, 2015
1302015
Tumor-associated B-cells induce tumor heterogeneity and therapy resistance
R Somasundaram, G Zhang, M Fukunaga-Kalabis, M Perego, C Krepler, ...
Nature communications 8 (1), 607, 2017
1282017
A modified HSP70 inhibitor shows broad activity as an anticancer agent
GM Balaburski, JIJ Leu, N Beeharry, S Hayik, MD Andrake, G Zhang, ...
Molecular Cancer Research 11 (3), 219-229, 2013
1162013
Targeting the Warburg effect via LDHA inhibition engages ATF 4 signaling for cancer cell survival
G Pathria, DA Scott, Y Feng, J Sang Lee, Y Fujita, G Zhang, AD Sahu, ...
The EMBO journal 37 (20), e99735, 2018
1152018
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