| O-Aryl-Glycoside Ice Recrystallization Inhibitors as Novel Cryoprotectants: A Structure–Function Study CJ Capicciotti, RS Mancini, TR Turner, T Koyama, MG Alteen, M Doshi, ... ACS omega 1 (4), 656-662, 2016 | 46 | 2016 |
| Direct One-Step Fluorescent Labeling of O-GlcNAc-Modified Proteins in Live Cells Using Metabolic Intermediates HY Tan, R Eskandari, D Shen, Y Zhu, TW Liu, LI Willems, MG Alteen, ... Journal of the American Chemical Society 140 (45), 15300-15308, 2018 | 40 | 2018 |
| Study of aggregation, denaturation and reduction of interferon alpha-2 products by size-exclusion high-performance liquid chromatography with fluorescence detection and … A Diress, B Lorbetskie, L Larocque, X Li, M Alteen, R Isbrucker, M Girard Journal of Chromatography A 1217 (19), 3297-3306, 2010 | 38 | 2010 |
| Catalytic Promiscuity of O-GlcNAc Transferase Enables Unexpected Metabolic Engineering of Cytoplasmic Proteins with 2-Azido-2-deoxy-glucose DL Shen, TW Liu, W Zandberg, T Clark, R Eskandari, MG Alteen, HY Tan, ... ACS chemical biology 12 (1), 206-213, 2017 | 33 | 2017 |
| Precision Mapping of O-Linked N-Acetylglucosamine Sites in Proteins Using Ultraviolet Photodissociation Mass Spectrometry EE Escobar, DT King, JE Serrano-Negrón, MG Alteen, DJ Vocadlo, ... Journal of the American Chemical Society 142 (26), 11569-11577, 2020 | 32 | 2020 |
| Monitoring and modulating O-GlcNAcylation: assays and inhibitors of O-GlcNAc processing enzymes MG Alteen, HY Tan, DJ Vocadlo Current opinion in structural biology 68, 157-165, 2021 | 31 | 2021 |
| A Direct Fluorescent Activity Assay for Glycosyltransferases Enables Convenient High‐Throughput Screening: Application to O‐GlcNAc Transferase MG Alteen, C Gros, RW Meek, DA Cardoso, JA Busmann, G Sangouard, ... Angewandte Chemie International Edition 59 (24), 9601-9609, 2020 | 25 | 2020 |
| Cryo-EM structure provides insights into the dimer arrangement of the O-linked β-N-acetylglucosamine transferase OGT RW Meek, JN Blaza, JA Busmann, MG Alteen, DJ Vocadlo, GJ Davies Nature Communications 12 (1), 6508, 2021 | 24 | 2021 |
| Mechanism of human nucleocytoplasmic hexosaminidase D MG Alteen, V Oehler, I Nemčovičová, IBH Wilson, DJ Vocadlo, ... Biochemistry 55 (19), 2735-2747, 2016 | 23 | 2016 |
| Characterization of Stackebrandtia nassauensis GH 20 Beta-Hexosaminidase, a Versatile Biocatalyst for Chitobiose Degradation M Wang, F Zheng, T Wang, YM Lyu, MG Alteen, ZP Cai, ZL Cui, L Liu, ... International Journal of Molecular Sciences 20 (5), 1243, 2019 | 15 | 2019 |
| Exploring the Potential of β-Catenin O-GlcNAcylation by Using Fluorescence-Based Engineering and Imaging A Kasprowicz, C Spriet, C Terryn, V Rigolot, S Hardiville, MG Alteen, ... Molecules 25 (19), 4501, 2020 | 14 | 2020 |
| The details of glycolipid glycan hydrolysis by the structural analysis of a family 123 glycoside hydrolase from Clostridium perfringens I Noach, B Pluvinage, C Laurie, KT Abe, MG Alteen, DJ Vocadlo, ... Journal of Molecular Biology 428 (16), 3253-3265, 2016 | 14 | 2016 |
| Potent De Novo Macrocyclic Peptides That Inhibit O‐GlcNAc Transferase through an Allosteric Mechanism MG Alteen, H Peacock, RW Meek, JA Busmann, S Zhu, GJ Davies, ... Angewandte Chemie International Edition 62 (5), e202215671, 2023 | 12 | 2023 |
| HBP/O-GlcNAcylation metabolic axis regulates bone resorption outcome TM Taira, ES Ramos-Junior, PH Melo, CC Costa-Silva, MG Alteen, ... Journal of Dental Research 102 (4), 440-449, 2023 | 6 | 2023 |
| Conformationally responsive dyes enable protein-adaptive differential scanning fluorimetry T Wu, CY Joshua, A Suresh, ZJ Gale-Day, MG Alteen, AS Woo, Z Millbern, ... bioRxiv, 2023 | 5 | 2023 |
| Phage display uncovers a sequence motif that drives polypeptide binding to a conserved regulatory exosite of O-GlcNAc transferase MG Alteen, RW Meek, S Kolappan, JA Busmann, J Cao, Z O’Gara, ... Proceedings of the National Academy of Sciences 120 (42), e2303690120, 2023 | 4 | 2023 |
| Discovery of a new drug-like series of OGT inhibitors by virtual screening EM Loi, T Tomašič, C Balsollier, K van Eekelen, M Weiss, M Gobec, ... Molecules 27 (6), 1996, 2022 | 4 | 2022 |
| Combinatorial anticancer drug screen identifies off-target effects of epigenetic chemical probes SH Barghout, MK Mann, A Aman, Y Yu, MG Alteen, AD Schimmer, ... ACS Chemical Biology 17 (10), 2801-2816, 2022 | 3 | 2022 |
| Human O-GlcNAcase Uses a Preactivated Boat-skew Substrate Conformation for Catalysis. Evidence from X-ray Crystallography and QM/MM Metadynamics M Calvelo, A Males, MG Alteen, LI Willems, DJ Vocadlo, GJ Davies, ... ACS catalysis 13 (20), 13672-13678, 2023 | 2 | 2023 |
| Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40 MG Alteen, JC Deme, CP Alvarez, P Loppnau, A Hutchinson, A Seitova, ... Structure 31 (9), 1121-1131. e6, 2023 | 1 | 2023 |
