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Helen Zhu
Helen Zhu
Verified email at uhnresearch.ca
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Integrative pathway enrichment analysis of multivariate omics data
M Paczkowska, J Barenboim, N Sintupisut, NS Fox, H Zhu, D Abd-Rabbo, ...
Nature communications 11 (1), 735, 2020
1182020
Candidate cancer driver mutations in distal regulatory elements and long-range chromatin interaction networks
H Zhu, L Uusküla-Reimand, K Isaev, L Wadi, A Alizada, S Shuai, V Huang, ...
Molecular cell 77 (6), 1307-1321. e10, 2020
602020
The transcriptional landscape of Shh medulloblastoma
P Skowron, H Farooq, FMG Cavalli, AS Morrissy, M Ly, LD Hendrikse, ...
Nature communications 12 (1), 1749, 2021
522021
Single-cell mapper (scMappR): using scRNA-seq to infer the cell-type specificities of differentially expressed genes
DJ Sokolowski, M Faykoo-Martinez, L Erdman, H Hou, C Chan, H Zhu, ...
NAR Genomics and Bioinformatics 3 (1), lqab011, 2021
172021
PCAWG Drivers and Functional Interpretation Working Group, Reimand J; PCAWG Consortium, Integrative pathway enrichment analysis of multivariate omics data
M Paczkowska, J Barenboim, N Sintupisut, NS Fox, H Zhu, D Abd-Rabbo, ...
Nat. Commun 11 (1), 735, 2020
172020
Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma
MM Kameda-Smith, H Zhu, EC Luo, Y Suk, A Xella, B Yee, C Chokshi, ...
Nature Communications 13 (1), 7506, 2022
52022
Functional Interpretation Working, G., et al.(2020)
M Paczkowska, J Barenboim, N Sintupisut, NS Fox, H Zhu, D Abd-Rabbo, ...
Integrative pathway enrichment analysis of multivariate omics data. Nat …, 0
5
PCAWG Drivers and Functional Interpretation Working Group, Reimand J et al (2020) Integrative pathway enrichment analysis of multivariate omics data
M Paczkowska, J Barenboim, N Sintupisut, NS Fox, H Zhu, D Abd-Rabbo, ...
Nat Commun 11, 735, 0
4
Mutations in Noncoding Cis-Regulatory Elements Reveal Cancer Driver Cistromes in Luminal Breast Cancer
S El Ghamrasni, R Quevedo, J Hawley, P Mazrooei, Y Hanna, I Cirlan, ...
Molecular Cancer Research 20 (1), 102-113, 2022
32022
An RNA foundation model enables discovery of disease mechanisms and candidate therapeutics
A Celaj, AJ Gao, TTY Lau, EM Holgersen, A Lo, V Lodaya, CB Cole, ...
bioRxiv, 2023.09. 20.558508, 2023
22023
A polygenic two-hit hypothesis for prostate cancer
KE Houlahan, J Livingstone, NS Fox, N Kurganovs, H Zhu, ...
JNCI: Journal of the National Cancer Institute 115 (4), 468-472, 2023
12023
An RNA foundation model enables discovery of disease mechanisms and candidate therapeutics
B Frey, A Celaj, A Gao, T Lau, E Holgersen, A Lo, V Lodaya, C Cole, ...
2023
Germline structural variants shape prostate cancer clinical and molecular evolution
NK Wang, A Rouette, KE Houlahan, TN Yamaguchi, J Livingstone, ...
Cancer Research 83 (7_Supplement), 4305-4305, 2023
2023
Author Correction: Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma
MM Kameda-Smith, H Zhu, EC Luo, Y Suk, A Xella, B Yee, C Chokshi, ...
nature communications 14, 2023
2023
Author Correction: Integrative pathway enrichment analysis of multivariate omics data
M Paczkowska, J Barenboim, N Sintupisut, NS Fox, H Zhu, D Abd-Rabbo, ...
nature communications 13 (1), 7570, 2022
2022
Germline determinants of the prostate tumor genome
KE Houlahan, J Yuan, T Schwarz, J Livingstone, NS Fox, W Jaratlerdsiri, ...
bioRxiv, 2022.11. 16.516773, 2022
2022
Characterization of an RNA binding protein interactome reveals the targetable post-transcriptional landscape of MYC-amplified medulloblastoma
M Kameda-Smith, H Zhu, EC Luo, C Venugopal, A Xella, B Yee, S Xing, ...
2022
C. 5 Musashi-1 is a master regulator of aberrant translation in MYC-amplified Group 3 medulloblastoma
MM Kameda-Smith, H Zhu, E Luo, C Venugopal, K Brown, BA Yee, S Xing, ...
Canadian Journal of Neurological Sciences 48 (s3), S19-S19, 2021
2021
Non-coding mutations reveal cancer driver cistromes in luminal breast cancer
SE Ghamrasni, R Quevedo, J Hawley, P Mazrooei, Y Hanna, I Cirlan, ...
bioRxiv, 2021.05. 29.446210, 2021
2021
MBRS-01. DISSECTING REGULATORS OF THE ABERRANT POST-TRANSCRIPTIONAL LANDSCAPE IN MYC-AMPLIFIED GROUP 3 MEDULLOBLASTOMA
M Kameda-Smith, H Zhu, EC Luo, C Venugopal, A Xella, K Brown, R Fox, ...
Neuro-oncology 22 (Suppl 3), iii399, 2020
2020
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