| TRPC3 and TRPC6 are essential for angiotensin II‐induced cardiac hypertrophy N Onohara, M Nishida, R Inoue, H Kobayashi, H Sumimoto, Y Sato, ... The EMBO journal 25 (22), 5305-5316, 2006 | 466 | 2006 |
| Monitoring G protein-coupled receptor and β-arrestin trafficking in live cells using enhanced bystander BRET Y Namkung, C Le Gouill, V Lukashova, H Kobayashi, M Hogue, E Khoury, ... Nature communications 7 (1), 12178, 2016 | 272 | 2016 |
| Gα12/13-and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat … M Nishida, S Tanabe, Y Maruyama, S Mangmool, K Urayama, ... Journal of Biological Chemistry 280 (18), 18434-18441, 2005 | 164 | 2005 |
| A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling A Beautrait, JS Paradis, B Zimmerman, J Giubilaro, L Nikolajev, ... Nature communications 8 (1), 15054, 2017 | 142 | 2017 |
| Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs C Avet, A Mancini, B Breton, C Le Gouill, AS Hauser, C Normand, ... Elife 11, e74101, 2022 | 110 | 2022 |
| Imidapril, an angiotensin-converting enzyme inhibitor, improves insulin sensitivity by enhancing signal transduction via insulin receptor substrate proteins and improving … M Nawano, M Anai, M Funaki, H Kobayashi, A Kanda, Y Fukushima, ... Metabolism 48 (10), 1248-1255, 1999 | 110 | 1999 |
| Gα12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts T Fujii, N Onohara, Y Maruyama, S Tanabe, H Kobayashi, M Fukutomi, ... Journal of Biological Chemistry 280 (24), 23041-23047, 2005 | 100 | 2005 |
| Bioluminescence resonance energy transfer–based imaging of protein–protein interactions in living cells H Kobayashi, LP Picard, AM Schönegge, M Bouvier Nature protocols 14 (4), 1084-1107, 2019 | 95 | 2019 |
| Functional Rescue of β1‐Adrenoceptor Dimerization and Trafficking by Pharmacological Chaperones H Kobayashi, K Ogawa, R Yao, O Lichtarge, M Bouvier Traffic 10 (8), 1019-1033, 2009 | 93 | 2009 |
| Systematic protein–protein interaction mapping for clinically relevant human GPCR s K Sokolina, S Kittanakom, J Snider, M Kotlyar, P Maurice, J Gandía, ... Molecular systems biology 13 (3), 918, 2017 | 85 | 2017 |
| Cyclobenzaprine, a centrally acting muscle relaxant, acts on descending serotonergic systems H Kobayashi, Y Hasegawa, H Ono European journal of pharmacology 311 (1), 29-35, 1996 | 63 | 1996 |
| Ser203 as well as Ser204 and Ser207 in fifth transmembrane domain of the human β2‐adrenoceptor contributes to agonist binding and receptor activation T Sato, H Kobayashi, T Nagao, H Kurose British journal of pharmacology 128 (2), 272-274, 1999 | 60 | 1999 |
| β-Arrestin2 enhances β2-adrenergic receptor-mediated nuclear translocation of ERK H Kobayashi, Y Narita, M Nishida, H Kurose Cellular signalling 17 (10), 1248-1253, 2005 | 53 | 2005 |
| Involvement of BKCa channels in the relaxation of detrusor muscle via β-adrenoceptors H Kobayashi, S Adachi-Akahane, T Nagao European journal of pharmacology 404 (1-2), 231-238, 2000 | 53 | 2000 |
| Clathrin required for phosphorylation and internalization of β2-adrenergic receptor by G protein-coupled receptor kinase 2 (GRK2) S Mangmool, T Haga, H Kobayashi, KM Kim, H Nakata, M Nishida, ... Journal of biological chemistry 281 (42), 31940-31949, 2006 | 48 | 2006 |
| KCTD hetero-oligomers confer unique kinetic properties on hippocampal GABAB receptor-induced K+ currents T Fritzius, R Turecek, R Seddik, H Kobayashi, J Tiao, PD Rem, M Metz, ... Journal of Neuroscience 37 (5), 1162-1175, 2017 | 46 | 2017 |
| Selectivity landscape of 100 therapeutically relevant GPCR profiled by an effector translocation-based BRET platform C Avet, A Mancini, B Breton, C Le Gouill, A Hauser, C Normand, ... | 41 | 2020 |
| Large conductance calcium-activated K channel opener M Hongu, T Hosaka, T Kashiwagi, R Kono, H Kobayashi US Patent 7,759,373, 2010 | 30 | 2010 |
| BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated Gq activation at early endosomes SC Wright, V Lukasheva, C Le Gouill, H Kobayashi, B Breton, ... Proceedings of the National Academy of Sciences 118 (20), e2025846118, 2021 | 25 | 2021 |
| Cys-27 variant of human δ-opioid receptor modulates maturation and cell surface delivery of Phe-27 variant via heteromerization TT Leskelä, JJ Lackman, MM Vierimaa, H Kobayashi, M Bouvier, ... Journal of Biological Chemistry 287 (7), 5008-5020, 2012 | 23 | 2012 |
Michel BouvierProfessor of Biochem. and Mol. Med., IRIC, Univ. de MontréalVerified email at umontreal.ca
