| Mitochondrial ClpP-mediated proteolysis induces selective cancer cell lethality J Ishizawa, SF Zarabi, RE Davis, O Halgas, T Nii, Y Jitkova, R Zhao, ... Cancer cell 35 (5), 721-737. e9, 2019 | 302 | 2019 |
| The role of ClpP protease in bacterial pathogenesis and human diseases V Bhandari, KS Wong, JL Zhou, MF Mabanglo, RA Batey, WA Houry ACS chemical biology 13 (6), 1413-1425, 2018 | 136 | 2018 |
| Acyldepsipeptide analogs dysregulate human mitochondrial ClpP protease activity and cause apoptotic cell death KS Wong, MF Mabanglo, TV Seraphim, A Mollica, YQ Mao, K Rizzolo, ... Cell chemical biology 25 (8), 1017-1030. e9, 2018 | 100 | 2018 |
| Variants of phosphotriesterase for the enhanced detoxification of the chemical warfare agent VR AN Bigley, MF Mabanglo, SP Harvey, FM Raushel Biochemistry 54 (35), 5502-5512, 2015 | 75 | 2015 |
| Reversible inhibition of the ClpP protease via an N-terminal conformational switch S Vahidi, ZA Ripstein, M Bonomi, T Yuwen, MF Mabanglo, JB Juravsky, ... Proceedings of the National Academy of Sciences 115 (28), E6447-E6456, 2018 | 60 | 2018 |
| Recent structural insights into the mechanism of ClpP protease regulation by AAA+ chaperones and small molecules MF Mabanglo, WA Houry Journal of Biological Chemistry 298 (5), 2022 | 43 | 2022 |
| Substrates and interactors of the ClpP protease in the mitochondria MF Mabanglo, V Bhandari, WA Houry Current Opinion in Chemical Biology 66, 102078, 2022 | 37 | 2022 |
| X-ray structures of isopentenyl phosphate kinase MF Mabanglo, HL Schubert, M Chen, CP Hill, CD Poulter ACS chemical biology 5 (5), 517-527, 2010 | 37 | 2010 |
| Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome MF Mabanglo, KS Wong, MM Barghash, E Leung, SHW Chuang, ... Structure 31 (2), 185-200. e10, 2023 | 30 | 2023 |
| Development of Antibiotics That Dysregulate the Neisserial ClpP Protease G Binepal, MF Mabanglo, JD Goodreid, E Leung, MM Barghash, ... ACS infectious diseases 6 (12), 3224-3236, 2020 | 26 | 2020 |
| ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores MF Mabanglo, E Leung, S Vahidi, TV Seraphim, BT Eger, S Bryson, ... Communications biology 2 (1), 410, 2019 | 26 | 2019 |
| Crystal structures of the fungal pathogen Aspergillus fumigatus protein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal … MF Mabanglo, MA Hast, NB Lubock, HW Hellinga, LS Beese Protein Science 23 (3), 289-301, 2014 | 23 | 2014 |
| Structure of a Novel Phosphotriesterase from Sphingobium sp. TCM1: A Familiar Binuclear Metal Center Embedded in a Seven-Bladed β-Propeller Protein Fold MF Mabanglo, DF Xiang, AN Bigley, FM Raushel Biochemistry 55 (28), 3963-3974, 2016 | 22 | 2016 |
| Mutagenesis of isopentenyl phosphate kinase to enhance geranyl phosphate kinase activity MF Mabanglo, JJ Pan, B Shakya, CD Poulter ACS chemical biology 7 (7), 1241-1246, 2012 | 16 | 2012 |
| Structure and reaction mechanism of the LigJ hydratase: an enzyme critical for the bacterial degradation of lignin in the protocatechuate 4, 5-cleavage pathway TN Hogancamp, MF Mabanglo, FM Raushel Biochemistry 57 (40), 5841-5850, 2018 | 14 | 2018 |
| The Streptomyces-Produced Antibiotic Fosfomycin Is a Promiscuous Substrate for Archaeal Isopentenyl Phosphate Kinase MF Mabanglo, AWR Serohijos, CD Poulter Biochemistry 51 (4), 917-925, 2012 | 10 | 2012 |
| Development of small molecules to modulate the activity of the ATP-dependent ClpP protease as a novel antibacterial and anticancer drug target F Lin, MF Mabanglo, WA Houry, RA Batey 2019 Medicinal Chemistry Reviews 54, 379-404, 2019 | 6 | 2019 |
| Structure and reaction mechanism of YcjR, an epimerase that facilitates the intercorversion of D-gulosides to D-glucosides in Escherichia coli MF Mabanglo, JP Huddleston, K Mukherjee, ZW Taylor, FM Raushel Biochemistry, 2020 | 3 | 2020 |
| Structure-Based design and development of phosphine oxides as a novel chemotype for antibiotics that dysregulate bacterial ClpP proteases F Lin, MF Mabanglo, JL Zhou, G Binepal, MM Barghash, KS Wong, ... Journal of Medicinal Chemistry 67 (17), 15131-15147, 2024 | 2 | 2024 |
| Development of Peptide Displacement Assays to Screen for Antagonists of DDB1 Interactions D Yong, S Ahmad, MF Mabanglo, L Halabelian, M Schapira, S Ackloo, ... Biochemistry, 2024 | 1 | 2024 |
