Marcus Lee
Marcus Lee
Wellcome Sanger Institute
Verified email at - Homepage
Cited by
Cited by
Spiroindolones, a potent compound class for the treatment of malaria
M Rottmann, C McNamara, BKS Yeung, MCS Lee, B Zou, B Russell, ...
science 329 (5996), 1175-1180, 2010
Bi-directional protein transport between the ER and Golgi
MCS Lee, EA Miller, J Goldberg, L Orci, R Schekman
Annu. Rev. Cell Dev. Biol. 20, 87-123, 2004
Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles
EA Miller, TH Beilharz, PN Malkus, MCS Lee, S Hamamoto, L Orci, ...
Cell 114 (4), 497-509, 2003
Sar1p N-terminal helix initiates membrane curvature and completes the fission of a COPII vesicle
MCS Lee, L Orci, S Hamamoto, E Futai, M Ravazzola, R Schekman
Cell 122 (4), 605-617, 2005
Targeting Plasmodium PI(4)K to eliminate malaria
CW McNamara, MCS Lee, CS Lim, SH Lim, J Roland, A Nagle, O Simon, ...
Nature 504 (7479), 248-253, 2013
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery
S Meister, DM Plouffe, KL Kuhen, GMC Bonamy, T Wu, SW Barnes, ...
Science 334 (6061), 1372-1377, 2011
A novel multiple-stage antimalarial agent that inhibits protein synthesis
B Baragaña, I Hallyburton, MCS Lee, NR Norcross, R Grimaldi, TD Otto, ...
Nature 522 (7556), 315-320, 2015
Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue
SH Adjalley, GL Johnston, T Li, RT Eastman, EH Ekland, AG Eappen, ...
Proceedings of the National Academy of Sciences 108 (47), E1214-E1223, 2011
(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium
MB Jiménez-Díaz, D Ebert, Y Salinas, A Pradhan, AM Lehane, ...
Proceedings of the National Academy of Sciences 111 (50), E5455-E5462, 2014
Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases
J Straimer, MCS Lee, AH Lee, B Zeitler, AE Williams, JR Pearl, L Zhang, ...
Nature methods 9 (10), 993-998, 2012
Ceramide biosynthesis is required for the formation of the oligomeric H+-ATPase Pma1p in the yeast endoplasmic reticulum
MCS Lee, S Hamamoto, R Schekman
Journal of Biological Chemistry 277 (25), 22395-22401, 2002
Proteinase inhibitors from Nicotiana alata enhance plant resistance to insect pests
RL Heath, G McDonald, JT Christeller, M Lee, K Bateman, J West, ...
Journal of Insect Physiology 43 (9), 833-842, 1997
Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase
T Paquet, C Le Manach, DG Cabrera, Y Younis, PP Henrich, TS Abraham, ...
Science translational medicine 9 (387), 2017
KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment, and prevention of disease transmission
KL Kuhen, AK Chatterjee, M Rottmann, K Gagaring, R Borboa, ...
Antimicrobial agents and chemotherapy 58 (9), 5060-5067, 2014
Molecular mechanisms of COPII vesicle formation
MCS Lee, EA Miller
Seminars in cell & developmental biology 18 (4), 424-434, 2007
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics
AN Cowell, ES Istvan, AK Lukens, MG Gomez-Lorenzo, M Vanaerschot, ...
Science 359 (6372), 191-199, 2018
A broad analysis of resistance development in the malaria parasite
VC Corey, AK Lukens, ES Istvan, MCS Lee, V Franco, P Magistrado, ...
Nature communications 7 (1), 1-9, 2016
Profiling the Essential Nature of Lipid Metabolism in Asexual Blood and Gametocyte Stages of Plasmodium falciparum
S Gulati, EH Ekland, KV Ruggles, RB Chan, B Jayabalasingham, B Zhou, ...
Cell Host & Microbe 18 (3), 371-381, 2015
Wherever I may roam: protein and membrane trafficking in P. falciparum-infected red blood cells
M Deponte, HC Hoppe, MCS Lee, AG Maier, D Richard, M Rug, ...
Molecular and biochemical parasitology 186 (2), 95-116, 2012
Inhibiting endoplasmic reticulum (ER)-associated degradation of misfolded Yor1p does not permit ER export despite the presence of a diacidic sorting signal
S Pagant, L Kung, M Dorrington, MCS Lee, EA Miller
Molecular biology of the cell 18 (9), 3398-3413, 2007
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