Denis Shields
Denis Shields
Professor of Clinical Bioinformatics, University College Dublin
Verified email at - Homepage
Cited by
Cited by
Molecular evidence for an ancient duplication of the entire yeast genome
KH Wolfe, DC Shields
Nature 387 (6634), 708-713, 1997
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
E Evangelou, HR Warren, D Mosen-Ansorena, B Mifsud, R Pazoki, H Gao, ...
Nature genetics 50 (10), 1412-1425, 2018
Codon usage patterns in Escherichia coli, Bacillus subtilis, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Drosophila melanogaster and Homo sapiens; a review of the …
PM Sharp, E Cowe, DG Higgins, DC Shields, KH Wolfe, F Wright
Nucleic acids research 16 (17), 8207-8211, 1988
" Silent" sites in Drosophila genes are not neutral: evidence of selection among synonymous codons.
DC Shields, PM Sharp, DG Higgins, F Wright
Molecular biology and evolution 5 (6), 704-716, 1988
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
HR Warren, E Evangelou, CP Cabrera, H Gao, M Ren, B Mifsud, I Ntalla, ...
Nature genetics 49 (3), 403-415, 2017
Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus
W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ...
PLoS genetics 6 (2), e1000841, 2010
A genetic defect in 5, 10 methylenetetrahydrofolate reductase in neural tube defects
AS Whitehead, P Gallagher, JL Mills, PN Kirke, H Burke, AM Molloy, ...
QJM: An International Journal of Medicine 88 (11), 763-766, 1995
Genome-Wide Association Study of Blood Pressure Extremes Identifies Variant near UMOD Associated with Hypertension
S Padmanabhan, O Melander, T Johnson, AM Di Blasio, WK Lee, ...
PLoS genetics 6 (10), e1001177, 2010
Towards the improved discovery and design of functional peptides: common features of diverse classes permit generalized prediction of bioactivity
C Mooney, NJ Haslam, G Pollastri, DC Shields
Public Library of Science 7 (10), e45012, 2012
Integration of proteomics and genomics in platelets: a profile of platelet proteins and platelet-specific genes
JP McRedmond, SD Park, DF Reilly, JA Coppinger, PB Maguire, ...
Molecular & Cellular Proteomics 3 (2), 133-144, 2004
Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders
M Den Hoed, M Eijgelsheim, T Esko, BJJM Brundel, DS Peal, DM Evans, ...
Nature genetics 45 (6), 621-631, 2013
Synonymous codon usage in Bacillus subtilis reflects both translational selection and mutational biases
DC Shields, PM Sharp
Nucleic acids research 15 (19), 8023-8040, 1987
Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations
DL Harmon, DC Shields, JV Woodside, D McMaster, JWG Yarnell, ...
Genetic Epidemiology: The Official Publication of the International Genetic …, 1999
Cyclooxygenase‐1 haplotype modulates platelet response to aspirin
AO Maree, RJ Curtin, A Chubb, C Dolan, D Cox, J O'brien, P Crean, ...
Journal of Thrombosis and Haemostasis 3 (10), 2340-2345, 2005
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci
R Saxena, CC Elbers, Y Guo, I Peter, TR Gaunt, JL Mega, MB Lanktree, ...
The American Journal of Human Genetics 90 (3), 410-425, 2012
Homocysteine and risk of premature coronary heart disease: evidence for a common gene mutation
PM Gallagher, R Meleady, DC Shields, KS Tan, D McMaster, R Rozen, ...
Circulation 94 (9), 2154-2158, 1996
The “thermolabile” variant of methylenetetrahydrofolate reductase and neural tube defects: an evaluation of genetic risk and the relative importance of the genotypes of the …
DC Shields, PN Kirke, JL Mills, D Ramsbottom, AM Molloy, H Burke, ...
The American journal of human genetics 64 (4), 1045-1055, 1999
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci
FW Asselbergs, Y Guo, EPA Van Iperen, S Sivapalaratnam, V Tragante, ...
The American Journal of Human Genetics 91 (5), 823-838, 2012
Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins
I Postmus, S Trompet, HA Deshmukh, MR Barnes, X Li, HR Warren, ...
Nature communications 5 (1), 5068, 2014
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip
PJ Talmud, F Drenos, S Shah, T Shah, J Palmen, C Verzilli, TR Gaunt, ...
The American journal of human genetics 85 (5), 628-642, 2009
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