Servio H. Ramirez PhD
Servio H. Ramirez PhD
Professor, Dept. of Pathology & Laboratory Medicine, Temple University School of Medicine
Verified email at - Homepage
Cited by
Cited by
Blood–brain barrier: structural components and function under physiologic and pathologic conditions
Y Persidsky, SH Ramirez, J Haorah, GD Kanmogne
Journal of Neuroimmune Pharmacology 1, 223-236, 2006
The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood–brain barrier
TP Buzhdygan, BJ DeOre, A Baldwin-Leclair, TA Bullock, HM McGary, ...
Neurobiology of disease 146, 105131, 2020
Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood–brain barrier dysfunction
J Haorah, SH Ramirez, K Schall, D Smith, R Pandya, Y Persidsky
Journal of neurochemistry 101 (2), 566-576, 2007
Mechanism of alcohol-induced oxidative stress and neuronal injury
J Haorah, SH Ramirez, N Floreani, S Gorantla, B Morsey, Y Persidsky
Free Radical Biology and Medicine 45 (11), 1542-1550, 2008
Phosphorylation of claudin-5 and occludin by rho kinase in brain endothelial cells
M Yamamoto, SH Ramirez, S Sato, T Kiyota, RL Cerny, K Kaibuchi, ...
The American journal of pathology 172 (2), 521-533, 2008
Activation of cannabinoid receptor 2 attenuates leukocyte–endothelial cell interactions and blood–brain barrier dysfunction under inflammatory conditions
SH Ramirez, J Haskó, A Skuba, S Fan, H Dykstra, R McCormick, ...
Journal of Neuroscience 32 (12), 4004-4016, 2012
Establishment of primary cultures of human brain microvascular endothelial cells to provide an in vitro cellular model of the blood-brain barrier
MJ Bernas, FL Cardoso, SK Daley, ME Weinand, AR Campos, ...
Nature protocols 5 (7), 1265-1272, 2010
Methamphetamine disrupts blood–brain barrier function by induction of oxidative stress in brain endothelial cells
SH Ramirez, R Potula, S Fan, T Eidem, A Papugani, N Reichenbach, ...
Journal of Cerebral Blood Flow & Metabolism 29 (12), 1933-1945, 2009
Blood biomarkers for brain injury: What are we measuring?
K Kawata, CY Liu, SF Merkel, SH Ramirez, RT Tierney, D Langford
Neuroscience & Biobehavioral Reviews 68, 460-473, 2016
HIV‐1 Tat‐mediated activation of glycogen synthase kinase‐3β contributes to Tat‐mediated neurotoxicity
SB Maggirwar, N Tong, S Ramirez, HA Gelbard, S Dewhurst
Journal of neurochemistry 73 (2), 578-586, 1999
Angiotensin II induced cerebral microvascular inflammation and increased blood–brain barrier permeability via oxidative stress
M Zhang, Y Mao, SH Ramirez, RF Tuma, T Chabrashvili
Neuroscience 171 (3), 852-858, 2010
Exosome-associated AAV vector as a robust and convenient neuroscience tool
E Hudry, C Martin, S Gandhi, B György, DI Scheffer, D Mu, SF Merkel, ...
Gene therapy 23 (4), 380-392, 2016
Emerging roles of pericytes in the regulation of the neurovascular unit in health and disease
J Hill, S Rom, SH Ramirez, Y Persidsky
Journal of Neuroimmune Pharmacology 9, 591-605, 2014
Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers
SH Ramirez, AM Andrews, D Paul, JS Pachter
Fluids and Barriers of the CNS 15 (1), 1-21, 2018
Trafficking of adeno‐associated virus vectors across a model of the blood–brain barrier; a comparative study of transcytosis and transduction using primary human brain …
SF Merkel, AM Andrews, EM Lutton, D Mu, E Hudry, BT Hyman, ...
Journal of neurochemistry 140 (2), 216-230, 2017
Inhibition of glycogen synthase kinase 3β promotes tight junction stability in brain endothelial cells by half-life extension of occludin and claudin-5
SH Ramirez, S Fan, H Dykstra, S Rom, A Mercer, NL Reichenbach, ...
PloS one 8 (2), e55972, 2013
Activation of protein tyrosine kinases and matrix metalloproteinases causes blood‐brain barrier injury: Novel mechanism for neurodegeneration associated with alcohol abuse
J Haorah, K Schall, SH Ramirez, Y Persidsky
Glia 56 (1), 78-88, 2008
Activation of glycogen synthase kinase 3 beta (GSK‐3β) by platelet activating factor mediates migration and cell death in cerebellar granule neurons
N Tong, JF Sanchez, SB Maggirwar, SH Ramirez, H Guo, S Dewhurst, ...
European Journal of Neuroscience 13 (10), 1913-1922, 2001
HIV infects astrocytes in vivo and egresses from the brain to the periphery
V Lutgen, SD Narasipura, HJ Barbian, M Richards, J Wallace, ...
PLoS pathogens 16 (6), e1008381, 2020
Activation of peroxisome proliferator-activated receptor γ (PPARγ) suppresses Rho GTPases in human brain microvascular endothelial cells and inhibits adhesion and …
SH Ramirez, D Heilman, B Morsey, R Potula, J Haorah, Y Persidsky
The Journal of Immunology 180 (3), 1854-1865, 2008
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