| SV2 is the protein receptor for botulinum neurotoxin A M Dong, F Yeh, WH Tepp, C Dean, EA Johnson, R Janz, ER Chapman Science 312 (5773), 592-596, 2006 | 914 | 2006 |
| Massively parallel de novo protein design for targeted therapeutics A Chevalier, DA Silva, GJ Rocklin, DR Hicks, R Vergara, P Murapa, ... Nature 550 (7674), 74-79, 2017 | 415 | 2017 |
| Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells M Dong, DA Richards, MC Goodnough, WH Tepp, EA Johnson, ... The Journal of cell biology 162 (7), 1293-1303, 2003 | 377 | 2003 |
| Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons M Dong, H Liu, WH Tepp, EA Johnson, R Janz, ER Chapman Molecular biology of the cell 19 (12), 5226-5237, 2008 | 289 | 2008 |
| Frizzled proteins are colonic epithelial receptors for C. difficile toxin B L Tao, J Zhang, P Meraner, A Tovaglieri, X Wu, R Gerhard, X Zhang, ... Nature 538 (7625), 350-355, 2016 | 276 | 2016 |
| Identification and characterization of a novel botulinum neurotoxin S Zhang, G Masuyer, J Zhang, Y Shen, D Lundin, L Henriksson, ... Nature communications 8 (1), 14130, 2017 | 252 | 2017 |
| Structural basis of cell surface receptor recognition by botulinum neurotoxin B Q Chai, JW Arndt, M Dong, WH Tepp, EA Johnson, ER Chapman, ... Nature 444 (7122), 1096-1100, 2006 | 240 | 2006 |
| Botulinum and tetanus neurotoxins M Dong, G Masuyer, P Stenmark Annual review of biochemistry 88, 811-837, 2019 | 193 | 2019 |
| Botulinum neurotoxin D uses synaptic vesicle protein SV2 and gangliosides as receptors L Peng, WH Tepp, EA Johnson, M Dong PLoS pathogens 7 (3), e1002008, 2011 | 172 | 2011 |
| Using fluorescent sensors to detect botulinum neurotoxin activity in vitro and in living cells M Dong, WH Tepp, EA Johnson, ER Chapman Proceedings of the National Academy of Sciences 101 (41), 14701-14706, 2004 | 163 | 2004 |
| SV2 mediates entry of tetanus neurotoxin into central neurons FL Yeh, M Dong, J Yao, WH Tepp, G Lin, EA Johnson, ER Chapman PLoS pathogens 6 (11), e1001207, 2010 | 153 | 2010 |
| Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium S Zhang, F Lebreton, MJ Mansfield, SI Miyashita, J Zhang, ... Cell host & microbe 23 (2), 169-176. e6, 2018 | 149 | 2018 |
| Mechanism of botulinum neurotoxin B and G entry into hippocampal neurons M Dong, WH Tepp, H Liu, EA Johnson, ER Chapman The Journal of cell biology 179 (7), 1511-1522, 2007 | 138 | 2007 |
| Botulinum neurotoxin DC uses synaptotagmin I and II as receptors, and human synaptotagmin II is not an effective receptor for type B, DC and G toxins L Peng, RPA Berntsson, WH Tepp, RM Pitkin, EA Johnson, P Stenmark, ... Journal of cell science 125 (13), 3233-3242, 2012 | 129 | 2012 |
| Autapses and networks of hippocampal neurons exhibit distinct synaptic transmission phenotypes in the absence of synaptotagmin I H Liu, C Dean, CP Arthur, M Dong, ER Chapman Journal of neuroscience 29 (23), 7395-7403, 2009 | 128 | 2009 |
| Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex K Lee, X Zhong, S Gu, AM Kruel, MB Dorner, K Perry, A Rummel, M Dong, ... Science 344 (6190), 1405-1410, 2014 | 123 | 2014 |
| Genetically encoded fluorescent indicators for imaging intracellular potassium ion concentration Y Shen, SY Wu, V Rancic, A Aggarwal, Y Qian, SI Miyashita, K Ballanyi, ... Communications biology 2 (1), 18, 2019 | 116 | 2019 |
| N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A G Yao, S Zhang, S Mahrhold, K Lam, D Stern, K Bagramyan, K Perry, ... Nature structural & molecular biology 23 (7), 656-662, 2016 | 113 | 2016 |
| Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B P Chen, L Tao, T Wang, J Zhang, A He, K Lam, Z Liu, X He, K Perry, ... Science 360 (6389), 664-669, 2018 | 112 | 2018 |
| Structure of dual receptor binding to botulinum neurotoxin B RPA Berntsson, L Peng, M Dong, P Stenmark Nature communications 4 (1), 2058, 2013 | 93 | 2013 |
