| The translational landscape of mTOR signalling steers cancer initiation and metastasis AC Hsieh, Y Liu, MP Edlind, NT Ingolia, MR Janes, A Sher, EY Shi, ... Nature 485 (7396), 55-61, 2012 | 1437 | 2012 |
| Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning N Kondrashov, A Pusic, CR Stumpf, K Shimizu, AC Hsieh, S Xue, ... Cell 145 (3), 383-397, 2011 | 616 | 2011 |
| Androgen receptor pathway-independent prostate cancer is sustained through FGF signaling EG Bluemn, IM Coleman, JM Lucas, RT Coleman, S Hernandez-Lopez, ... Cancer cell 32 (4), 474-489. e6, 2017 | 593 | 2017 |
| Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E AC Hsieh, M Costa, O Zollo, C Davis, ME Feldman, JR Testa, O Meyuhas, ... Cancer cell 17 (3), 249-261, 2010 | 533 | 2010 |
| Pseudouridylation of tRNA-derived fragments steers translational control in stem cells N Guzzi, M Cieśla, PCT Ngoc, S Lang, S Arora, M Dimitriou, K Pimková, ... Cell 173 (5), 1204-1216. e26, 2018 | 346 | 2018 |
| A library of sirna duplexes targeting the phosphoinositide 3‐kinase pathway: determinants of gene silencing for use in cell‐based screens AC Hsieh, R Bo, J Manola, F Vazquez, O Bare, A Khvorova, S Scaringe, ... Nucleic acids research 32 (3), 893-901, 2004 | 293 | 2004 |
| PI3K-AKT-mTOR signaling in prostate cancer progression and androgen deprivation therapy resistance MP Edlind, AC Hsieh Asian journal of andrology 16 (3), 378, 2014 | 286 | 2014 |
| Molecular profiling stratifies diverse phenotypes of treatment-refractory metastatic castration-resistant prostate cancer MP Labrecque, IM Coleman, LG Brown, LD True, L Kollath, B Lakely, ... The Journal of clinical investigation 129 (10), 2019 | 270 | 2019 |
| Targeting eukaryotic translation initiation factor 4E (eIF4E) in cancer AC Hsieh, D Ruggero Clinical cancer research 16 (20), 4914-4920, 2010 | 237 | 2010 |
| Development of a stress response therapy targeting aggressive prostate cancer HG Nguyen, CS Conn, Y Kye, L Xue, CM Forester, JE Cowan, AC Hsieh, ... Science translational medicine 10 (439), eaar2036, 2018 | 146 | 2018 |
| Assessing gene-level translational control from ribosome profiling AB Olshen, AC Hsieh, CR Stumpf, RA Olshen, D Ruggero, BS Taylor Bioinformatics 29 (23), 2995-3002, 2013 | 106 | 2013 |
| The untranslated regions of mRNAs in cancer SL Schuster, AC Hsieh Trends in cancer, 2019 | 95 | 2019 |
| MTOR Modulators and Uses Thereof KM Shokat, D Fruman, P Ren, TE Wilson, L Li, A Hsieh, M Feldman, ... US Patent App. 13/003,562, 2011 | 94 | 2011 |
| Oncogenic AKTivation of translation as a therapeutic target AC Hsieh, ML Truitt, D Ruggero British Journal of Cancer 105 (3), 329-336, 2011 | 88 | 2011 |
| Genomic characterization of prostatic ductal adenocarcinoma identifies a high prevalence of DNA repair gene mutations MT Schweizer, ES Antonarakis, TA Bismar, LB Guedes, HH Cheng, ... JCO precision oncology 3, 1-9, 2019 | 86 | 2019 |
| A phase II study of the dual mTOR inhibitor MLN0128 in patients with metastatic castration resistant prostate cancer L Graham, K Banda, A Torres, BS Carver, Y Chen, K Pisano, G Shelkey, ... Investigational new drugs 36 (3), 458-467, 2018 | 72 | 2018 |
| The androgen receptor regulates a druggable translational regulon in advanced prostate cancer Y Liu, JL Horn, K Banda, AZ Goodman, Y Lim, S Jana, S Arora, ... Science translational medicine 11 (503), eaaw4993, 2019 | 53 | 2019 |
| N 6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis DA Kuppers, S Arora, Y Lim, AR Lim, LM Carter, PD Corrin, CL Plaisier, ... Nature communications 10 (1), 1-17, 2019 | 49 | 2019 |
| A phase I study of abiraterone acetate combined with BEZ235, a dual PI3K/mTOR inhibitor, in metastatic castration resistant prostate cancer XX Wei, AC Hsieh, W Kim, T Friedlander, AM Lin, M Louttit, CJ Ryan The oncologist 22 (5), 503, 2017 | 49 | 2017 |
| Cell type–specific abundance of 4EBP1 primes prostate cancer sensitivity or resistance to PI3K pathway inhibitors AC Hsieh, HG Nguyen, L Wen, MP Edlind, PR Carroll, W Kim, D Ruggero Sci. Signal. 8 (403), ra116-ra116, 2015 | 45 | 2015 |
