| Co-assembly of polycystin-1 and-2 produces unique cation-permeable currents K Hanaoka, F Qian, A Boletta, AK Bhunia, K Piontek, L Tsiokas, ... Nature 408 (6815), 990-994, 2000 | 957 | 2000 |
| PKD1 induces p21waf1 and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2 AK Bhunia, K Piontek, A Boletta, L Liu, F Qian, PN Xu, FJ Germino, ... Cell 109 (2), 157-168, 2002 | 543 | 2002 |
| Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy I Rowe, M Chiaravalli, V Mannella, V Ulisse, G Quilici, M Pema, XW Song, ... Nature medicine 19 (4), 488-493, 2013 | 470 | 2013 |
| Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations F Qian, A Boletta, AK Bhunia, H Xu, L Liu, AK Ahrabi, TJ Watnick, F Zhou, ... Proceedings of the National Academy of Sciences 99 (26), 16981-16986, 2002 | 359 | 2002 |
| Nonviral gene delivery to the rat kidney with polyethylenimine A Boletta, A Benigni, J Lutz, G Remuzzi, MR Soria, L Monaco Human gene therapy 8 (10), 1243-1251, 1997 | 267 | 1997 |
| Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells A Boletta, F Qian, LF Onuchic, AK Bhunia, B Phakdeekitcharoen, ... Molecular cell 6 (5), 1267-1273, 2000 | 266 | 2000 |
| Polycystin-1 regulates extracellular signal-regulated kinase-dependent phosphorylation of tuberin to control cell size through mTOR and its downstream effectors S6K and 4EBP1 G Distefano, M Boca, I Rowe, C Wodarczyk, L Ma, KB Piontek, ... Molecular and cellular biology 29 (9), 2359-2371, 2009 | 229 | 2009 |
| Comparison between cationic polymers and lipids in mediating systemic gene delivery to the lungs A Bragonzi, A Boletta, A Biffi, A Muggia, G Sersale, SH Cheng, ... Gene therapy 6 (12), 1995-2004, 1999 | 221 | 1999 |
| PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium function I Franco, F Gulluni, CC Campa, C Costa, JP Margaria, E Ciraolo, ... Developmental cell 28 (6), 647-658, 2014 | 203 | 2014 |
| 2-Deoxy-d-glucose ameliorates PKD progression M Chiaravalli, I Rowe, V Mannella, G Quilici, T Canu, V Bianchi, ... Journal of the American Society of Nephrology 27 (7), 1958-1969, 2016 | 162 | 2016 |
| Metabolism and mitochondria in polycystic kidney disease research and therapy V Padovano, C Podrini, A Boletta, MJ Caplan Nature Reviews Nephrology 14 (11), 678-687, 2018 | 141 | 2018 |
| Role of polycystins in renal tubulogenesis A Boletta, GG Germino Trends in cell biology 13 (9), 484-492, 2003 | 141 | 2003 |
| Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism H Kim, H Xu, Q Yao, W Li, Q Huang, P Outeda, V Cebotaru, M Chiaravalli, ... Nature communications 5 (1), 5482, 2014 | 119 | 2014 |
| Prospects for mTOR inhibitor use in patients with polycystic kidney disease and hamartomatous diseases VE Torres, A Boletta, A Chapman, V Gattone, Y Pei, Q Qian, DP Wallace, ... Clinical Journal of the American Society of Nephrology 5 (7), 1312-1329, 2010 | 119 | 2010 |
| Polycystin-1 induces resistance to apoptosis through the phosphatidylinositol 3-kinase/Akt signaling pathway M Boca, G Distefano, F Qian, AK Bhunia, GG Germino, A Boletta Journal of the American society of nephrology 17 (3), 637-647, 2006 | 118 | 2006 |
| Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3β-dependent cell–cell mechanical adhesion M Boca, L D'Amato, G Distefano, RS Polishchuk, GG Germino, A Boletta Molecular biology of the cell 18 (10), 4050-4061, 2007 | 117 | 2007 |
| Emerging evidence of a link between the polycystins and the mTOR pathways A Boletta Pathogenetics 2, 1-16, 2009 | 103 | 2009 |
| A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus C Wodarczyk, I Rowe, M Chiaravalli, M Pema, F Qian, A Boletta PloS one 4 (9), e7137, 2009 | 96 | 2009 |
| The polycystins are modulated by cellular oxygen-sensing pathways and regulate mitochondrial function V Padovano, IY Kuo, LK Stavola, HR Aerni, BJ Flaherty, HC Chapin, M Ma, ... Molecular biology of the cell 28 (2), 261-269, 2017 | 84 | 2017 |
| Renal-retinal ciliopathy gene Sdccag8 regulates DNA damage response signaling R Airik, GG Slaats, Z Guo, AC Weiss, N Khan, A Ghosh, TW Hurd, ... Journal of the American Society of Nephrology 25 (11), 2573-2583, 2014 | 83 | 2014 |
