Suivre
Nathiya Muthalagu
Nathiya Muthalagu
Asst.Professor, Dept. of Biotechnology, IIT Madras
Adresse e-mail validée de iitm.ac.in
Titre
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Année
Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death
G Ichim, J Lopez, SU Ahmed, N Muthalagu, E Giampazolias, ME Delgado, ...
Molecular cell 57 (5), 860-872, 2015
3992015
Deregulated MYC expression induces dependence upon AMPK-related kinase 5
L Liu, J Ulbrich, J Müller, T Wüstefeld, L Aeberhard, TR Kress, ...
Nature 483 (7391), 608-612, 2012
2982012
Developmental regulation of mitochondrial apoptosis by c-Myc governs age-and tissue-specific sensitivity to cancer therapeutics
KA Sarosiek, C Fraser, N Muthalagu, PD Bhola, W Chang, SK McBrayer, ...
Cancer cell 31 (1), 142-156, 2017
2382017
Glutamine anabolism plays a critical role in pancreatic cancer by coupling carbon and nitrogen metabolism
AJ Bott, J Shen, C Tonelli, L Zhan, N Sivaram, YP Jiang, X Yu, V Bhatt, ...
Cell reports 29 (5), 1287-1298. e6, 2019
1362019
Repression of the type I interferon pathway underlies MYC-and KRAS-dependent evasion of NK and B cells in pancreatic ductal adenocarcinoma
N Muthalagu, T Monteverde, X Raffo-Iraolagoitia, R Wiesheu, D Whyte, ...
Cancer discovery 10 (6), 872-887, 2020
1162020
MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance
AS Farrell, MM Joly, BL Allen-Petersen, PJ Worth, C Lanciault, D Sauer, ...
Nature communications 8 (1), 1728, 2017
942017
Evidence of cancer‐promoting roles for AMPK and related kinases
T Monteverde, N Muthalagu, J Port, DJ Murphy
The FEBS journal 282 (24), 4658-4671, 2015
912015
BIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues
N Muthalagu, MR Junttila, KE Wiese, E Wolf, J Morton, B Bauer, GI Evan, ...
Cell reports 8 (5), 1347-1353, 2014
822014
Colorectal tumors require NUAK1 for protection from oxidative stress
J Port, N Muthalagu, M Raja, F Ceteci, T Monteverde, B Kruspig, A Hedley, ...
Cancer discovery 8 (5), 632-647, 2018
672018
Repression of the type I interferon pathway underlies MYC-and KRAS-dependent evasion of NK and B cells in pancreatic ductal adenocarcinoma. Cancer Discov. 2020; 10: 872–887 …
N Muthalagu, T Monteverde, X Raffo-Iraolagoitia, R Wiesheu, D Whyte, ...
CD-19-0620.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
18
NUAK1 governs centrosome replication in pancreatic cancer via MYPT1/PP1β and GSK3β‐dependent regulation of PLK4
D Whyte, G Skalka, P Walsh, A Wilczynska, NR Paul, C Mitchell, C Nixon, ...
Molecular Oncology 17 (7), 1212-1227, 2023
32023
Is oxidative stress MYC’s Achilles heel?
N Muthalagu, DJ Murphy
Cell Death and Differentiation 25 (7), 1189, 2018
32018
BIM's up first
DJ Murphy, N Muthalagu
Molecular & Cellular Oncology 2 (2), e975083, 2015
12015
RNA-SEQ analysis of human U2OS cells with/without depletion of NUAK1 by shRNA
N Muthalagu, G Kalna, A Hedley, D Murphy
ArrayExpress, 2018
2018
The AMPK-related kinase NUAK1 is a target for treatment of colorectal cancer
J Port, N Muthalagu, M Raja, T Monteverde, M Mezna, F Ceteci, G Murray, ...
European Journal of Cancer 1 (61), S68, 2016
2016
Stabilization of Wild-Type MLL Displaces Oncogenic MLL Fusion Proteins
KA Sarosiek, C Fraser, N Muthalagu, PD Bhola, W Chang, SK McBrayer
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