Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy P Koppula, L Zhuang, B Gan Protein & cell 12 (8), 599-620, 2021 | 991 | 2021 |
DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer C Mao, X Liu, Y Zhang, G Lei, Y Yan, H Lee, P Koppula, S Wu, L Zhuang, ... Nature 593 (7860), 586-590, 2021 | 895 | 2021 |
The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression G Lei, Y Zhang, P Koppula, X Liu, J Zhang, SH Lin, JA Ajani, Q Xiao, ... Cell research 30 (2), 146-162, 2020 | 744 | 2020 |
BAP1 links metabolic regulation of ferroptosis to tumour suppression Y Zhang, J Shi, X Liu, L Feng, Z Gong, P Koppula, K Sirohi, X Li, Y Wei, ... Nature cell biology 20 (10), 1181-1192, 2018 | 663 | 2018 |
Amino acid transporter SLC7A11/xCT at the crossroads of regulating redox homeostasis and nutrient dependency of cancer P Koppula, Y Zhang, L Zhuang, B Gan Cancer communications 38, 1-13, 2018 | 578 | 2018 |
mTORC1 couples cyst (e) ine availability with GPX4 protein synthesis and ferroptosis regulation Y Zhang, RV Swanda, L Nie, X Liu, C Wang, H Lee, G Lei, C Mao, ... Nature communications 12 (1), 1-14, 2021 | 378 | 2021 |
Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer X Liu, K Olszewski, Y Zhang, EW Lim, J Shi, X Zhang, J Zhang, H Lee, ... Nature cell biology 22 (4), 476-486, 2020 | 286 | 2020 |
The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate P Koppula, Y Zhang, J Shi, W Li, B Gan Journal of Biological Chemistry 292 (34), 14240-14249, 2017 | 219 | 2017 |
A targetable CoQ-FSP1 axis drives ferroptosis-and radiation-resistance in KEAP1 inactive lung cancers P Koppula, G Lei, Y Zhang, Y Yan, C Mao, L Kondiparthi, J Shi, X Liu, ... Nature communications 13 (1), 2206, 2022 | 173 | 2022 |
FABP4 as a key determinant of metastatic potential of ovarian cancer KM Gharpure, S Pradeep, M Sans, R Rupaimoole, C Ivan, SY Wu, ... Nature communications 9 (1), 1-14, 2018 | 168 | 2018 |
Ferroptosis as a mechanism to mediate p53 function in tumor radiosensitivity G Lei, Y Zhang, T Hong, X Zhang, X Liu, C Mao, Y Yan, P Koppula, ... Oncogene 40 (20), 3533-3547, 2021 | 120 | 2021 |
Regulation of H2A ubiquitination and SLC7A11 expression by BAP1 and PRC1 Y Zhang, P Koppula, B Gan Cell Cycle 18 (8), 773-783, 2019 | 95 | 2019 |
Cytochrome P450 reductase (POR) as a ferroptosis fuel P Koppula, L Zhuang, B Gan Protein & Cell 12 (9), 675-679, 2021 | 44 | 2021 |
H2A monoubiquitination links glucose availability to epigenetic regulation of the endoplasmic reticulum stress response and cancer cell death Y Zhang, J Shi, X Liu, Z Xiao, G Lei, H Lee, P Koppula, W Cheng, C Mao, ... Cancer research 80 (11), 2243-2256, 2020 | 30 | 2020 |
KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition P Koppula, K Olszewski, Y Zhang, L Kondiparthi, X Liu, G Lei, M Das, ... Iscience 24 (6), 2021 | 27 | 2021 |
Author Correction: DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer C Mao, X Liu, Y Zhang, G Lei, Y Yan, H Lee, P Koppula, S Wu, L Zhuang, ... Nature 596 (7873), E13-E13, 2021 | 17 | 2021 |
Central metabolic sensing remotely controls nutrient-sensitive endocrine response in Drosophila via Sir2/Sirt1–upd2–IIS axis KK Banerjee, RS Deshpande, P Koppula, C Ayyub, U Kolthur-Seetharam Journal of Experimental Biology 220 (7), 1187-1191, 2017 | 13 | 2017 |
DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer., 2021, 593 C Mao, X Liu, Y Zhang, G Lei, Y Yan, H Lee, P Koppula, S Wu, L Zhuang, ... DOI: https://doi. org/10.1038/s41586-021-03539-7, 586-590, 2021 | 4 | 2021 |
Thiol profiling in cancer cell lines by HPLC-mass spectrometry X Liu, P Koppula, K Olszewski, B Gan STAR protocols 2 (4), 100977, 2021 | 3 | 2021 |
Cell cycle arrest induces lipid droplet formation and confers ferroptosis resistance H Lee, A Horbath, L Kondiparthi, JK Meena, G Lei, S Dasgupta, X Liu, ... Nature communications 15 (1), 79, 2024 | 1 | 2024 |