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Pranavi Koppula
Pranavi Koppula
University of Texas M D Anderson Cancer Centre
Verified email at mdanderson.org - Homepage
Title
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Cited by
Year
Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy
P Koppula, L Zhuang, B Gan
Protein & cell 12 (8), 599-620, 2021
9912021
DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer
C Mao, X Liu, Y Zhang, G Lei, Y Yan, H Lee, P Koppula, S Wu, L Zhuang, ...
Nature 593 (7860), 586-590, 2021
8952021
The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression
G Lei, Y Zhang, P Koppula, X Liu, J Zhang, SH Lin, JA Ajani, Q Xiao, ...
Cell research 30 (2), 146-162, 2020
7442020
BAP1 links metabolic regulation of ferroptosis to tumour suppression
Y Zhang, J Shi, X Liu, L Feng, Z Gong, P Koppula, K Sirohi, X Li, Y Wei, ...
Nature cell biology 20 (10), 1181-1192, 2018
6632018
Amino acid transporter SLC7A11/xCT at the crossroads of regulating redox homeostasis and nutrient dependency of cancer
P Koppula, Y Zhang, L Zhuang, B Gan
Cancer communications 38, 1-13, 2018
5782018
mTORC1 couples cyst (e) ine availability with GPX4 protein synthesis and ferroptosis regulation
Y Zhang, RV Swanda, L Nie, X Liu, C Wang, H Lee, G Lei, C Mao, ...
Nature communications 12 (1), 1-14, 2021
3782021
Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer
X Liu, K Olszewski, Y Zhang, EW Lim, J Shi, X Zhang, J Zhang, H Lee, ...
Nature cell biology 22 (4), 476-486, 2020
2862020
The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate
P Koppula, Y Zhang, J Shi, W Li, B Gan
Journal of Biological Chemistry 292 (34), 14240-14249, 2017
2192017
A targetable CoQ-FSP1 axis drives ferroptosis-and radiation-resistance in KEAP1 inactive lung cancers
P Koppula, G Lei, Y Zhang, Y Yan, C Mao, L Kondiparthi, J Shi, X Liu, ...
Nature communications 13 (1), 2206, 2022
1732022
FABP4 as a key determinant of metastatic potential of ovarian cancer
KM Gharpure, S Pradeep, M Sans, R Rupaimoole, C Ivan, SY Wu, ...
Nature communications 9 (1), 1-14, 2018
1682018
Ferroptosis as a mechanism to mediate p53 function in tumor radiosensitivity
G Lei, Y Zhang, T Hong, X Zhang, X Liu, C Mao, Y Yan, P Koppula, ...
Oncogene 40 (20), 3533-3547, 2021
1202021
Regulation of H2A ubiquitination and SLC7A11 expression by BAP1 and PRC1
Y Zhang, P Koppula, B Gan
Cell Cycle 18 (8), 773-783, 2019
952019
Cytochrome P450 reductase (POR) as a ferroptosis fuel
P Koppula, L Zhuang, B Gan
Protein & Cell 12 (9), 675-679, 2021
442021
H2A monoubiquitination links glucose availability to epigenetic regulation of the endoplasmic reticulum stress response and cancer cell death
Y Zhang, J Shi, X Liu, Z Xiao, G Lei, H Lee, P Koppula, W Cheng, C Mao, ...
Cancer research 80 (11), 2243-2256, 2020
302020
KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition
P Koppula, K Olszewski, Y Zhang, L Kondiparthi, X Liu, G Lei, M Das, ...
Iscience 24 (6), 2021
272021
Author Correction: DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer
C Mao, X Liu, Y Zhang, G Lei, Y Yan, H Lee, P Koppula, S Wu, L Zhuang, ...
Nature 596 (7873), E13-E13, 2021
172021
Central metabolic sensing remotely controls nutrient-sensitive endocrine response in Drosophila via Sir2/Sirt1–upd2–IIS axis
KK Banerjee, RS Deshpande, P Koppula, C Ayyub, U Kolthur-Seetharam
Journal of Experimental Biology 220 (7), 1187-1191, 2017
132017
DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer., 2021, 593
C Mao, X Liu, Y Zhang, G Lei, Y Yan, H Lee, P Koppula, S Wu, L Zhuang, ...
DOI: https://doi. org/10.1038/s41586-021-03539-7, 586-590, 2021
42021
Thiol profiling in cancer cell lines by HPLC-mass spectrometry
X Liu, P Koppula, K Olszewski, B Gan
STAR protocols 2 (4), 100977, 2021
32021
Cell cycle arrest induces lipid droplet formation and confers ferroptosis resistance
H Lee, A Horbath, L Kondiparthi, JK Meena, G Lei, S Dasgupta, X Liu, ...
Nature communications 15 (1), 79, 2024
12024
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