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Luke Michael Healy
Luke Michael Healy
Adjunct Assistant Professor, McGill University
Verified email at tcd.ie
Title
Cited by
Cited by
Year
iPSC-derived human microglia-like cells to study neurological diseases
EM Abud, RN Ramirez, ES Martinez, LM Healy, CHH Nguyen, ...
Neuron 94 (2), 278-293. e9, 2017
9622017
Microglial control of astrocytes in response to microbial metabolites
V Rothhammer, DM Borucki, EC Tjon, MC Takenaka, CC Chao, ...
Nature 557 (7707), 724-728, 2018
9042018
Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype
K Gabrusiewicz, B Rodriguez, J Wei, Y Hashimoto, LM Healy, SN Maiti, ...
JCI insight 1 (2), 2016
4492016
Roles of microglia in brain development, tissue maintenance and repair
M Michell-Robinson, H Touil, L Healy, D Owen, B Durafourt, A Bar-Or, ...
Brain 138 (5), 1138-1159, 2015
4382015
Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39
MC Takenaka, G Gabriely, V Rothhammer, ID Mascanfroni, MA Wheeler, ...
Nature neuroscience 22 (5), 729-740, 2019
4112019
Development of a chimeric model to study and manipulate human microglia in vivo
J Hasselmann, MA Coburn, W England, DXF Velez, SK Shabestari, ...
Neuron 103 (6), 1016-1033. e10, 2019
2962019
Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes
K Gabrusiewicz, X Li, J Wei, Y Hashimoto, AL Marisetty, M Ott, F Wang, ...
Oncoimmunology 7 (4), e1412909, 2018
2912018
Peripherally derived macrophages modulate microglial function to reduce inflammation after CNS injury
AD Greenhalgh, JG Zarruk, LM Healy, SJ Baskar Jesudasan, P Jhelum, ...
PLoS biology 16 (10), e2005264, 2018
2072018
Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans
DR Owen, N Narayan, L Wells, L Healy, E Smyth, EA Rabiner, ...
Journal of Cerebral Blood Flow & Metabolism 37 (8), 2679-2690, 2017
2012017
Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation
V Rothhammer, JE Kenison, E Tjon, MC Takenaka, KA de Lima, ...
Proceedings of the National Academy of Sciences 114 (8), 2012-2017, 2017
1932017
MerTK Is a Functional Regulator of Myelin Phagocytosis by Human Myeloid Cells
L Healy, SY Perron, Gabrielle, Won, M Michell-Robinson, A Rezk, ...
Journal of Immunology 196 (8), 3375-3384, 2016
1672016
Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson’s disease brain
J Rostami, G Fotaki, J Sirois, R Mzezewa, J Bergström, M Essand, L Healy, ...
Journal of Neuroinflammation 17, 1-18, 2020
1532020
Crosstalk between astrocytes and microglia results in increased degradation of α-synuclein and amyloid-β aggregates
J Rostami, T Mothes, M Kolahdouzan, O Eriksson, M Moslem, J Bergström, ...
Journal of neuroinflammation 18 (1), 124, 2021
1342021
Lesion stage-dependent causes for impaired remyelination in MS
K Heß, L Starost, NW Kieran, C Thomas, MCJ Vincenten, J Antel, ...
Acta neuropathologica 140, 359-375, 2020
1152020
Cytokine-Defined B Cell Responses as Therapeutic Targets in Multiple Sclerosis
R Li, A Rezk, L Healy, G Muirhead, A Prat, J Gommerman, A Bar-Or, ...
Frontiers in Immunology, 2015
1152015
pHERV-W envelope protein fuels microglial cell-dependent damage of myelinated axons in multiple sclerosis
D Kremer, J Gruchot, V Weyers, L Oldemeier, P Göttle, L Healy, J Ho Jang, ...
Proceedings of the National Academy of Sciences 116 (30), 15216-15225, 2019
1052019
Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72
C Laflamme, PM McKeever, R Kumar, J Schwartz, M Kolahdouzan, ...
Elife 8, e48363, 2019
1012019
USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation
S Torre, MJ Polyak, D Langlais, N Fodil, JM Kennedy, I Radovanovic, ...
Nature immunology 18 (1), 54-63, 2017
962017
The role of glial cells in multiple sclerosis disease progression
LM Healy, JA Stratton, T Kuhlmann, J Antel
Nature Reviews Neurology 18 (4), 237-248, 2022
932022
Single-cell RNA sequencing reveals time-and sex-specific responses of mouse spinal cord microglia to peripheral nerve injury and links ApoE to chronic pain
S Tansley, S Uttam, A Ureña Guzmán, M Yaqubi, A Pacis, M Parisien, ...
Nature communications 13 (1), 843, 2022
852022
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