Inhibitory inputs from rostromedial tegmental neurons regulate spontaneous activity of midbrain dopamine cells and their responses to drugs of abuse S Lecca, M Melis, A Luchicchi, AL Muntoni, M Pistis Neuropsychopharmacology 37 (5), 1164-1176, 2012 | 217 | 2012 |
The lateral habenula in addiction and depression: an anatomical, synaptic and behavioral overview S Lecca, FJ Meye, M Mameli European Journal of Neuroscience 39 (7), 1170-1178, 2014 | 193 | 2014 |
Effects of drugs of abuse on putative rostromedial tegmental neurons, inhibitory afferents to midbrain dopamine cells S Lecca, M Melis, A Luchicchi, MG Ennas, MP Castelli, AL Muntoni, ... Neuropsychopharmacology 36 (3), 589-602, 2011 | 175 | 2011 |
Rescue of GABAB and GIRK function in the lateral habenula by protein phosphatase 2A inhibition ameliorates depression-like phenotypes in mice S Lecca, A Pelosi, A Tchenio, I Moutkine, R Lujan, D Hervé, M Mameli Nature medicine 22 (3), 254-261, 2016 | 146 | 2016 |
Blockade of nicotine reward and reinstatement by activation of alpha-type peroxisome proliferator-activated receptors P Mascia, M Pistis, Z Justinova, LV Panlilio, A Luchicchi, S Lecca, ... Biological psychiatry 69 (7), 633-641, 2011 | 136 | 2011 |
Aversive stimuli drive hypothalamus-to-habenula excitation to promote escape behavior S Lecca, FJ Meye, M Trusel, A Tchenio, J Harris, MK Schwarz, ... Elife 6, e30697, 2017 | 126 | 2017 |
PPARα regulates cholinergic-driven activity of midbrain dopamine neurons via a novel mechanism involving α7 nicotinic acetylcholine receptors M Melis, S Scheggi, G Carta, C Madeddu, S Lecca, A Luchicchi, ... Journal of Neuroscience 33 (14), 6203-6211, 2013 | 102 | 2013 |
Effects of fatty acid amide hydrolase inhibition on neuronal responses to nicotine, cocaine and morphine in the nucleus accumbens shell and ventral tegmental area: involvement … A Luchicchi, S Lecca, S Carta, G Pillolla, AL Muntoni, S Yasar, ... Addiction biology 15 (3), 277, 2010 | 101 | 2010 |
Cocaine-evoked negative symptoms require AMPA receptor trafficking in the lateral habenula FJ Meye, K Valentinova, S Lecca, L Marion-Poll, MJ Maroteaux, ... Nature neuroscience 18 (3), 376-378, 2015 | 95 | 2015 |
Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments F Petrelli, G Dallérac, L Pucci, C Calì, T Zehnder, S Sultan, S Lecca, ... Molecular psychiatry 25 (4), 732-749, 2020 | 90 | 2020 |
Limiting habenular hyperactivity ameliorates maternal separation-driven depressive-like symptoms A Tchenio, S Lecca, K Valentinova, M Mameli Nature communications 8 (1), 1135, 2017 | 90 | 2017 |
Enhanced serotonin and mesolimbic dopamine transmissions in a rat model of neuropathic pain C Sagheddu, S Aroni, M De Felice, S Lecca, A Luchicchi, M Melis, ... Neuropharmacology 97, 383-393, 2015 | 90 | 2015 |
Synaptic and cellular profile of neurons in the lateral habenula FJ Meye, S Lecca, K Valentinova, M Mameli Frontiers in human neuroscience 7, 860, 2013 | 88 | 2013 |
Maternal immune activation disrupts dopamine system in the offspring A Luchicchi, S Lecca, M Melis, M De Felice, F Cadeddu, R Frau, ... International Journal of Neuropsychopharmacology 19 (7), pyw007, 2016 | 83 | 2016 |
Novel use of a lipid-lowering fibrate medication to prevent nicotine reward and relapse: preclinical findings LV Panlilio, Z Justinova, P Mascia, M Pistis, A Luchicchi, S Lecca, ... Neuropsychopharmacology 37 (8), 1838-1847, 2012 | 80 | 2012 |
Punishment-predictive cues guide avoidance through potentiation of hypothalamus-to-habenula synapses M Trusel, A Nuno-Perez, S Lecca, H Harada, AL Lalive, M Congiu, ... Neuron 102 (1), 120-127. e4, 2019 | 78 | 2019 |
Adolescent Δ9-tetrahydrocannabinol exposure alters WIN55, 212-2 self-administration in adult rats M Scherma, C Dessì, AL Muntoni, S Lecca, V Satta, A Luchicchi, M Pistis, ... Neuropsychopharmacology 41 (5), 1416-1426, 2016 | 71 | 2016 |
The absence of VGLUT3 predisposes to cocaine abuse by increasing dopamine and glutamate signaling in the nucleus accumbens DY Sakae, F Marti, S Lecca, F Vorspan, E Martín-García, LJ Morel, ... Molecular psychiatry 20 (11), 1448-1459, 2015 | 66 | 2015 |
PPAR-alpha agonists as novel antiepileptic drugs: preclinical findings M Puligheddu, G Pillolla, M Melis, S Lecca, F Marrosu, MG De Montis, ... PLoS One 8 (5), e64541, 2013 | 63 | 2013 |
Sex-specific tonic 2-arachidonoylglycerol signaling at inhibitory inputs onto dopamine neurons of Lister Hooded rats M Melis, M De Felice, S Lecca, L Fattore, M Pistis Frontiers in integrative neuroscience 7, 70477, 2013 | 59 | 2013 |