| Fexinidazole: a potential new drug candidate for Chagas disease MT Bahia, IM Andrade, TAF Martins, ÁFS Nascimento, LF Diniz, IS Caldas, ... PLoS neglected tropical diseases 6 (11), e1870, 2012 | 190 | 2012 |
| Benznidazole and posaconazole in experimental Chagas disease: positive interaction in concomitant and sequential treatments LF Diniz, JA Urbina, IM de Andrade, AL Mazzeti, TAF Martins, IS Caldas, ... PLoS neglected tropical diseases 7 (8), e2367, 2013 | 150 | 2013 |
| Benznidazole therapy during acute phase of Chagas disease reduces parasite load but does not prevent chronic cardiac lesions IS Caldas, A Talvani, S Caldas, CM Carneiro, M de Lana, ... Parasitology research 103, 413-421, 2008 | 112 | 2008 |
| Effects of Ravuconazole Treatment on Parasite Load and Immune Response in Dogs Experimentally Infected with Trypanosoma cruzi LF Diniz, IS Caldas, PMM Guedes, G Crepalde, M de Lana, CM Carneiro, ... Antimicrobial agents and chemotherapy 54 (7), 2979-2986, 2010 | 108 | 2010 |
| Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-γ, TNF-α, and low IL-10 production during the acute infection phase PMM Guedes, VM Veloso, LCC Afonso, MV Caliari, CM Carneiro, ... Veterinary immunology and immunopathology 130 (1-2), 43-52, 2009 | 89 | 2009 |
| Real-time PCR strategy for parasite quantification in blood and tissue samples of experimental Trypanosoma cruzi infection S Caldas, IS Caldas, L de Figueiredo Diniz, WG de Lima, ... Acta tropica 123 (3), 170-177, 2012 | 85 | 2012 |
| Antitrypanosomal activity of fexinidazole metabolites, potential new drug candidates for Chagas disease MT Bahia, AFS Nascimento, AL Mazzeti, LF Marques, KR Gonçalves, ... Antimicrobial agents and chemotherapy 58 (8), 4362-4370, 2014 | 82 | 2014 |
| The correlation between chemical structures and antioxidant, prooxidant, and antitrypanosomatid properties of flavonoids JL Baldim, BGV Alcântara, OS Domingos, MG Soares, IS Caldas, ... Oxidative Medicine and Cellular Longevity 2017, 2017 | 71 | 2017 |
| Curcumin enhances the anti-Trypanosoma cruzi activity of benznidazole-based chemotherapy in acute experimental Chagas disease RD Novaes, MVP Sartini, JPF Rodrigues, RV Gonçalves, EC Santos, ... Antimicrobial agents and chemotherapy 60 (6), 3355-3364, 2016 | 64 | 2016 |
| Benznidazole/Itraconazole Combination Treatment Enhances Anti-Trypanosoma cruzi Activity in Experimental Chagas Disease T Assíria Fontes Martins, L de Figueiredo Diniz, AL Mazzeti, ... PLoS One 10 (6), e0128707, 2015 | 62 | 2015 |
| Increased type 1 chemokine expression in experimental Chagas disease correlates with cardiac pathology in beagle dogs PMM Guedes, VM Veloso, A Talvani, LF Diniz, IS Caldas, ... Veterinary Immunology and Immunopathology 138 (1-2), 106-113, 2010 | 50 | 2010 |
| An evaluation of benznidazole as a Chagas disease therapeutic IS Caldas, EG Santos, RD Novaes Expert opinion on pharmacotherapy 20 (15), 1797-1807, 2019 | 49 | 2019 |
| Applicability of plant-based products in the treatment of Trypanosoma cruzi and Trypanosoma brucei infections: a systematic review of preclinical in vivo evidence RM Pereira, GMZ Greco, AM Moreira, PF Chagas, IS Caldas, ... Parasitology 144 (10), 1275-1287, 2017 | 46 | 2017 |
| Outcome of E1224-benznidazole combination treatment for infection with a multidrug-resistant Trypanosoma cruzi strain in mice LF Diniz, AL Mazzeti, IS Caldas, I Ribeiro, MT Bahia Antimicrobial Agents and Chemotherapy 62 (6), 10.1128/aac. 00401-18, 2018 | 45 | 2018 |
| Low doses of simvastatin therapy ameliorate cardiac inflammatory remodeling in Trypanosoma cruzi-infected dogs L Melo, IS Caldas, MA Azevedo, KR Gonçalves, AFS do Nascimento, ... The American journal of tropical medicine and hygiene 84 (2), 325, 2011 | 45 | 2011 |
| S. mansoni-T. cruzi co-infection modulates arginase-1/iNOS expression, liver and heart disease in mice JPF Rodrigues, IS Caldas, RV Gonçalves, LA Almeida, RLM Souza, ... Nitric Oxide 66, 43-52, 2017 | 41 | 2017 |
| Recombinant Leishmania (Leishmania) infantum Ecto-Nucleoside Triphosphate Diphosphohydrolase NTPDase-2 as a new antigen in canine visceral leishmaniasis diagnosis RF de Souza, YL Dos Santos, R de Souza Vasconcellos, ... Acta tropica 125 (1), 60-66, 2013 | 38 | 2013 |
| Myocardial scars correlate with eletrocardiographic changes in chronic Trypanosoma cruzi infection for dogs treated with Benznidazole IS Caldas, PM da Matta Guedes, FM dos Santos, L de Figueiredo Diniz, ... Tropical Medicine & International Health 18 (1), 75-84, 2013 | 37 | 2013 |
| Impairment of interleukin-17A expression in canine visceral leishmaniosis is correlated with reduced interferon-γ and inducible nitric oxide synthase expression MSL Nascimento, TDR Albuquerque, AFS Nascimento, IS Caldas, ... Journal of comparative pathology 153 (4), 197-205, 2015 | 36 | 2015 |
| Challenges of immunosuppressive and antitrypanosomal drug therapy after heart transplantation in patients with chronic Chagas disease: a systematic review of clinical … SS Nogueira, AA Felizardo, IS Caldas, RV Goncalves, RD Novaes Transplantation Reviews 32 (3), 157-167, 2018 | 35 | 2018 |
