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Lan Guan, MD, PhD
Lan Guan, MD, PhD
Texas Tech University Health Sciences Center
Verified email at ttuhsc.edu
Title
Cited by
Cited by
Year
Maltose–neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins
PS Chae, SGF Rasmussen, RR Rana, K Gotfryd, R Chandra, MA Goren, ...
Nature methods 7 (12), 1003-1008, 2010
5182010
Lessons from lactose permease
L Guan, HR Kaback
Annu. Rev. Biophys. Biomol. Struct. 35, 67-91, 2006
3752006
Structural determination of wild-type lactose permease
L Guan, O Mirza, G Verner, S Iwata, HR Kaback
Proceedings of the National Academy of Sciences 104 (39), 15294-15298, 2007
2442007
Structural evidence for induced fit and a mechanism for sugar/H+ symport in LacY
O Mirza, L Guan, G Verner, S Iwata, HR Kaback
The EMBO Journal 25 (6), 1177-1183, 2006
2072006
Identification of Essential Charged Residues in Transmembrane Segments of the Multidrug Transporter MexB ofPseudomonas aeruginosa
L Guan, T Nakae
Journal of bacteriology 183 (5), 1734-1739, 2001
1572001
A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins
PS Chae, SGF Rasmussen, RR Rana, K Gotfryd, AC Kruse, A Manglik, ...
Chemistry–A European Journal 18 (31), 9485-9490, 2012
1482012
Structure-based mechanism for Na+/melibiose symport by MelB
SA Ethayathulla, SM Yousef, A Amin, G Leblanc, HR Kaback, L Guan
Nature Communications 5 (Article number: 3009), doi:10.1038/ncomms4009, 2014
1472014
An approach to membrane protein structure without crystals
PL Sorgen, Y Hu, L Guan, HR Kaback, ME Girvin
Proceedings of the National Academy of Sciences 99 (22), 14037-14040, 2002
1182002
Manipulating phospholipids for crystallization of a membrane transport protein
L Guan, IN Smirnova, G Verner, S Nagamori, HR Kaback
Proceedings of the National Academy of Sciences 103 (6), 1723-1726, 2006
1082006
Opening and closing of the periplasmic gate in lactose permease
Y Zhou, L Guan, JA Freites, HR Kaback
Proceedings of the National Academy of Sciences 105 (10), 3774-3778, 2008
1002008
Membrane topology of the xenobiotic-exporting subunit, MexB, of the MexA, B-OprM extrusion pump in Pseudomonas aeruginosa
L Guan, M Ehrmann, H Yoneyama, T Nakae
Journal of Biological Chemistry 274 (15), 10517-10522, 1999
991999
Crystal structure of lactose permease in complex with an affinity inactivator yields unique insight into sugar recognition
V Chaptal, S Kwon, MR Sawaya, L Guan, HR Kaback, J Abramson
Proceedings of the National Academy of Sciences 108 (23), 9361-9366, 2011
982011
Aromatic stacking in the sugar binding site of the lactose permease
L Guan, Y Hu, HR Kaback
Biochemistry 42 (6), 1377-1382, 2003
802003
Exploiting luminescence spectroscopy to elucidate the interaction between sugar and a tryptophan residue in the lactose permease of Escherichia coli
JL Vázquez-Ibar, L Guan, M Svrakic, HR Kaback
Proceedings of the National Academy of Sciences 100 (22), 12706-12711, 2003
692003
Mechanism of melibiose/cation symport of the melibiose permease of Salmonella typhimurium
L Guan, S Nurva, SP Ankeshwarapu
Journal of biological chemistry 286 (8), 6367-6374, 2011
672011
Site-directed alkylation of cysteine to test solvent accessibility of membrane proteins
L Guan, H Ronald Kaback
Nature protocols 2 (8), 2012-2017, 2007
622007
Binding affinity of lactose permease is not altered by the H+ electrochemical gradient
L Guan, HR Kaback
Proceedings of the National Academy of Sciences 101 (33), 12148-12152, 2004
622004
Surface-exposed positions in the transmembrane helices of the lactose permease of Escherichia coli determined by intermolecular thiol cross-linking
L Guan, FD Murphy, HR Kaback
Proceedings of the National Academy of Sciences 99 (6), 3475-3480, 2002
602002
Highly branched pentasaccharide-bearing amphiphiles for membrane protein studies
M Ehsan, Y Du, NJ Scull, E Tikhonova, J Tarrasch, JS Mortensen, ...
Journal of the American Chemical Society 138 (11), 3789-3796, 2016
592016
Maltose neopentyl glycol-3 (MNG-3) analogues for membrane protein study
KH Cho, M Husri, A Amin, K Gotfryd, HJ Lee, J Go, JW Kim, CJ Loland, ...
Analyst 140 (9), 3157-3163, 2015
562015
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