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Denis Tikhonov
Denis Tikhonov
I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry, St.Petersburg, Russia
Verified email at iephb.ru
Title
Cited by
Cited by
Year
Modeling P-loops domain of sodium channel: homology with potassium channels and interaction with ligands
DB Tikhonov, BS Zhorov
Biophysical journal 88 (1), 184-197, 2005
1492005
Potassium, sodium, calcium and glutamate‐gated channels: pore architecture and ligand action
BS Zhorov, DB Tikhonov
Journal of neurochemistry 88 (4), 782-799, 2004
1422004
Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants
DB Tikhonov, BS Zhorov
The Journal of general physiology 149 (4), 465-481, 2017
1242017
Determinants of trapping block of N‐methyl‐d‐aspartate receptor channels
KV Bolshakov, VE Gmiro, DB Tikhonov, LG Magazanik
Journal of neurochemistry 87 (1), 56-65, 2003
1232003
Architecture and pore block of eukaryotic voltage-gated sodium channels in view of NavAb bacterial sodium channel structure
DB Tikhonov, BS Zhorov
Molecular pharmacology 82 (1), 97-104, 2012
1132012
Structural model for dihydropyridine binding to L-type calcium channels
DB Tikhonov, BS Zhorov
Journal of Biological Chemistry 284 (28), 19006-19017, 2009
1102009
Influence of external magnesium ions on the NMDA receptor channel block by different types of organic cations
MV Nikolaev, LG Magazanik, DB Tikhonov
Neuropharmacology 62 (5-6), 2078-2085, 2012
902012
Design of antagonists for NMDA and AMPA receptors
KV Bolshakov, KH Kim, NN Potapjeva, VE Gmiro, DB Tikhonov, ...
Neuropharmacology 49 (2), 144-155, 2005
852005
How batrachotoxin modifies the sodium channel permeation pathway: computer modeling and site-directed mutagenesis
SY Wang, J Mitchell, DB Tikhonov, BS Zhorov, GK Wang
Molecular pharmacology 69 (3), 788-795, 2006
822006
Access and binding of local anesthetics in the closed sodium channel
I Bruhova, DB Tikhonov, BS Zhorov
Molecular pharmacology 74 (4), 1033-1045, 2008
802008
Inhibition of the NMDA and AMPA receptor channels by antidepressants and antipsychotics
OI Barygin, EI Nagaeva, DB Tikhonov, DA Belinskaya, NP Vanchakova, ...
Brain research 1660, 58-66, 2017
782017
Sodium channel activators: model of binding inside the pore and a possible mechanism of action
DB Tikhonov, BS Zhorov
FEBS letters 579 (20), 4207-4212, 2005
772005
Sodium channels: ionic model of slow inactivation and state-dependent drug binding
DB Tikhonov, BS Zhorov
Biophysical journal 93 (5), 1557-1570, 2007
692007
Characterization of acid-sensitive ion channels in freshly isolated rat brain neurons
KV Bolshakov, KV Essin, SL Buldakova, NA Dorofeeva, SN Skatchkov, ...
Neuroscience 110 (4), 723-730, 2002
672002
Modeling of the pore domain of the GLUR1 channel: homology with K+ channel and binding of channel blockers
DB Tikhonov, JR Mellor, PNR Usherwood, LG Magazanik
Biophysical journal 82 (4), 1884-1893, 2002
672002
Structural model for phenylalkylamine binding to L-type calcium channels
RCK Cheng, DB Tikhonov, BS Zhorov
Journal of Biological Chemistry 284 (41), 28332-28342, 2009
652009
Different arrangement of hydrophobic and nucleophilic components of channel binding sites in N-methyl-D-aspartate and AMPA receptors of rat brain is revealed by channel blockade
KV Bolshakov, DB Tikhonov, VE Gmiro, LG Magazanik
Neuroscience letters 291 (2), 101-104, 2000
652000
Voltage‐dependent block of native AMPA receptor channels by dicationic compounds
DB Tikhonov, MV Samoilova, SL Buldakova, VE Gmiro, LG Magazanik
British journal of pharmacology 129 (2), 265-274, 2000
652000
Solid-phase synthesis and biological evaluation of a combinatorial library of philanthotoxin analogues
K Strømgaard, TJ Brier, K Andersen, IR Mellor, A Saghyan, D Tikhonov, ...
Journal of medicinal chemistry 43 (23), 4526-4533, 2000
582000
Origin and molecular evolution of ionotropic glutamate receptors
DB Tikhonov, LG Magazanik
Neuroscience and behavioral physiology 39 (8), 763-773, 2009
562009
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Articles 1–20