Kivanc Birsoy
Kivanc Birsoy
Chapman-Perelman Assistant Professor, Rockefeller University
Verified email at - Homepage
Cited by
Cited by
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer
R Possemato, KM Marks, YD Shaul, ME Pacold, D Kim, K Birsoy, ...
Nature 476 (7360), 346-350, 2011
Identification and characterization of essential genes in the human genome
T Wang, K Birsoy, NW Hughes, KM Krupczak, Y Post, JJ Wei, ES Lander, ...
Science 350 (6264), 1096-1101, 2015
Identification of white adipocyte progenitor cells in vivo
MS Rodeheffer, K Birsoy, JM Friedman
Cell 135 (2), 240-249, 2008
An essential role of the mitochondrial electron transport chain in cell proliferation is to enable aspartate synthesis
K Birsoy, T Wang, WW Chen, E Freinkman, M Abu-Remaileh, DM Sabatini
Cell 162 (3), 540-551, 2015
mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake
ÖH Yilmaz, P Katajisto, DW Lamming, Y Gültekin, KE Bauer-Rowe, ...
Nature 486 (7404), 490-495, 2012
Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides
K Birsoy, R Possemato, FK Lorbeer, EC Bayraktar, P Thiru, B Yucel, ...
Nature 508 (7494), 108-112, 2014
A diverse array of cancer-associated MTOR mutations are hyperactivating and can predict rapamycin sensitivity
BC Grabiner, V Nardi, K Birsoy, R Possemato, K Shen, S Sinha, A Jordan, ...
Cancer discovery 4 (5), 554-563, 2014
Transcriptional regulation of adipogenesis by KLF4
K Birsoy, Z Chen, J Friedman
Cell metabolism 7 (4), 339-347, 2008
Antidiabetic effects of IGFBP2, a leptin-regulated gene
K Hedbacker, K Birsoy, RW Wysocki, E Asilmaz, RS Ahima, IS Farooqi, ...
Cell metabolism 11 (1), 11-22, 2010
A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate
ME Pacold, KR Brimacombe, SH Chan, JM Rohde, CA Lewis, ...
Nature chemical biology 12 (6), 452-458, 2016
SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance
D Kim, BP Fiske, K Birsoy, E Freinkman, K Kami, RL Possemato, ...
Nature 520 (7547), 363-367, 2015
MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors
K Birsoy, T Wang, R Possemato, OH Yilmaz, CE Koch, WW Chen, ...
Nature Genetics, 2013
Molecular Profiling of Activated Neurons by Phosphorylated Ribosome Capture
ZA Knight, K Tan, K Birsoy, S Schmidt, JL Garrison, RW Wysocki, ...
Cell 151 (5), 1126-1137, 2012
Absolute quantification of matrix metabolites reveals the dynamics of mitochondrial metabolism
WW Chen, E Freinkman, T Wang, K Birsoy, DM Sabatini
Cell 166 (5), 1324-1337. e11, 2016
NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis
SW Alvarez, VO Sviderskiy, EM Terzi, T Papagiannakopoulos, AL Moreira, ...
Nature 551 (7682), 639-643, 2017
Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours
J Garcia-Bermudez, L Baudrier, K La, XG Zhu, J Fidelin, VO Sviderskiy, ...
Nature cell biology 20 (7), 775-781, 2018
Adipocyte-derived lipids mediate melanoma progression via FATP proteins
M Zhang, JS Di Martino, RL Bowman, NR Campbell, SC Baksh, ...
Cancer discovery 8 (8), 1006-1025, 2018
DEPTOR cell-autonomously promotes adipogenesis, and its expression is associated with obesity
M Laplante, S Horvat, WT Festuccia, K Birsoy, Z Prevorsek, A Efeyan, ...
Cell metabolism 16 (2), 202-212, 2012
Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death
J Garcia-Bermudez, L Baudrier, EC Bayraktar, Y Shen, K La, ...
Nature 567 (7746), 118-122, 2019
A comparative perspective on lipid storage in animals
K Birsoy, WT Festuccia, M Laplante
Journal of cell science 126 (7), 1541-1552, 2013
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