Mike Sutcliffe
Mike Sutcliffe
Deputy Dean, TEDI-London
Verified email at tedi-london.ac.uk
Title
Cited by
Cited by
Year
Knowledge based modelling of homologous proteins, Part I: Three-dimensional frameworks derived from the simultaneous superposition of multiple structures
MJ Sutcliffe, I Haneef, D Carney, TL Blundell
Protein Engineering, Design and Selection 1 (5), 377-384, 1987
5291987
An automated approach for clustering an ensemble of NMR-derived protein structures into conformationally related subfamilies
LA Kelley, SP Gardner, MJ Sutcliffe
Protein Engineering, Design and Selection 9 (11), 1063-1065, 1996
4591996
Crystal structure of a PDZ domain
JHM Cabral, C Petosa, MJ Sutcliffe, S Raza, O Byron, F Poy, SM Marfatia, ...
Nature 382 (6592), 649-652, 1996
3681996
Atomic description of an enzyme reaction dominated by proton tunneling
L Masgrau, A Roujeinikova, LO Johannissen, P Hothi, J Basran, ...
Science 312 (5771), 237-241, 2006
3502006
Knowledge‐based protein modelling and design
T Blundell, D Carney, S Gardner, F Hayes, B Howlin, T Hubbard, ...
European Journal of Biochemistry 172 (3), 513-520, 1988
3251988
Knowledge based modelling of homologous proteins, Part II: Rules for the conformations of substituted sidechains
MJ Sutcliffe, FRF Hayes, TL Blundell
Protein Engineering, Design and Selection 1 (5), 385-392, 1987
3121987
Enzymatic H-transfer requires vibration-driven extreme tunneling
J Basran, MJ Sutcliffe, NS Scrutton
Biochemistry 38 (10), 3218-3222, 1999
2661999
A single aspartate residue is involved in both intrinsic gating and blockage by Mg2+ of the inward rectifier, IRK1.
PR Stanfield, NW Davies, PA Shelton, MJ Sutcliffe, IA Khan, WJ Brammar, ...
The Journal of physiology 478 (1), 1-6, 1994
2221994
Ligand binding to integrin αIIbβ3 is dependent on a MIDAS-like domain in the β3 subunit
EC Tozer, RC Liddington, MJ Sutcliffe, AH Smeeton, JC Loftus
Journal of Biological Chemistry 271 (36), 21978-21984, 1996
2081996
A model for human cytochrome P450 2D6 based on homology modeling and NMR studies of substrate binding
S Modi, MJ Paine, MJ Sutcliffe, LY Lian, WU Primrose, CR Wolf, ...
Biochemistry 35 (14), 4540-4550, 1996
2061996
Cytochrome P450 6M2 from the malaria vector Anopheles gambiae metabolizes pyrethroids: sequential metabolism of deltamethrin revealed
BJ Stevenson, J Bibby, P Pignatelli, S Muangnoicharoen, PM O’Neill, ...
Insect biochemistry and molecular biology 41 (7), 492-502, 2011
2012011
A single mutation in cytochrome P450 BM3 changes substrate orientation in a catalytic intermediate and the regiospecificity of hydroxylation
CF Oliver, S Modi, MJ Sutcliffe, WU Primrose, LY Lian, GCK Roberts
Biochemistry 36 (7), 1567-1572, 1997
1831997
TRAIL receptor-selective mutants signal to apoptosis via TRAIL-R1 in primary lymphoid malignancies
M MacFarlane, SL Kohlhaas, MJ Sutcliffe, MJS Dyer, GM Cohen
Cancer research 65 (24), 11265-11270, 2005
1752005
A new conceptual framework for enzyme catalysis: Hydrogen tunneling coupled to enzyme dynamics in flavoprotein and quinoprotein enzymes
MJ Sutcliffe, NS Scrutton
European Journal of Biochemistry 269 (13), 3096-3102, 2002
1562002
The catalytic mechanism of cytochrome P450 BM3 involves a 6 movement of the bound substrate on reduction
S Modi, MJ Sutcliffe, WU Primrose, LY Lian, GCK Roberts
Nature structural biology 3 (5), 414-417, 1996
1511996
Structure of hen lysozyme in solution
LJ Smith, MJ Sutcliffe, C Redfield, CM Dobson
Journal of molecular biology 229 (4), 930-944, 1993
1471993
Island dynamics in a braided river from analysis of historical maps and air photographs
L Zanoni, A Gurnell, N Drake, N Surian
River Research and Applications 24 (8), 1141-1159, 2008
1462008
Biodiversity of cytochrome P450 redox systems
KJ McLean, M Sabri, KR Marshall, RJ Lawson, DG Lewis, D Clift, ...
Biochemical Society Transactions 33 (4), 796-801, 2005
1402005
Analysis of. vphi. and. chi. 1 torsion angles for hen lysozyme in solution from proton NMR spin-spin coupling constants
LJ Smith, MJ Sutcliffe, C Redfield, CM Dobson
Biochemistry 30 (4), 986-996, 1991
1381991
Residues glutamate 216 and aspartate 301 are key determinants of substrate specificity and product regioselectivity in cytochrome P450 2D6
MJI Paine, LA McLaughlin, JU Flanagan, CA Kemp, MJ Sutcliffe, ...
Journal of Biological Chemistry 278 (6), 4021-4027, 2003
1272003
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