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Robert C Cumming
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Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
A Simonsen, RC Cumming, A Brech, P Isakson, DR Schubert, KD Finley
Autophagy 4 (2), 176-184, 2008
7932008
Protein disulfide bond formation in the cytoplasm during oxidative stress
RC Cumming, NL Andon, PA Haynes, M Park, WH Fischer, D Schubert
Journal of biological chemistry 279 (21), 21749-21758, 2004
5672004
The regulation of glucose metabolism by HIF-1 mediates a neuroprotective response to amyloid beta peptide
T Soucek, R Cumming, R Dargusch, P Maher, D Schubert
Neuron 39 (1), 43-56, 2003
3032003
Fanconi anemia group C protein prevents apoptosis in hematopoietic cells through redox regulation of GSTP1
RC Cumming, J Lightfoot, K Beard, H Youssoufian, PJ O'Brien, ...
Nature medicine 7 (7), 814-820, 2001
2922001
Analysis of gene expression in a complex differentiation hierarchy by global amplification of cDNA from single cells
G Brady, F Billia, J Knox, T Hoang, IR Kirsch, EB Voura, RG Hawley, ...
Current Biology 5 (8), 909-922, 1995
2321995
p62, Ref (2) P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects
BJ Bartlett, P Isakson, J Lewerenz, H Sanchez, RW Kotzebue, ...
Autophagy 7 (6), 572-583, 2011
2162011
Amyloid‐β induces disulfide bonding and aggregation of GAPDH in Alzheimer's disease
RC Cumming, D Schubert
The FASEB journal 19 (14), 2060-2062, 2005
1562005
Amyloid beta resistance in nerve cell lines is mediated by the Warburg effect
JT Newington, A Pitts, A Chien, R Arseneault, D Schubert, RC Cumming
PloS one 6 (4), e19191, 2011
1202011
Reevaluating metabolism in Alzheimer's disease from the perspective of the astrocyte-neuron lactate shuttle model
JT Newington, RA Harris, RC Cumming
Journal of neurodegenerative diseases 2013, 2013
1182013
Overexpression of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase A in nerve cells confers resistance to amyloid β and other toxins by decreasing mitochondrial …
JT Newington, T Rappon, S Albers, DY Wong, RJ Rylett, RC Cumming
Journal of Biological Chemistry 287 (44), 37245-37258, 2012
1152012
Suppression of apoptosis in hematopoietic factor-dependent progenitor cell lines by expression of the FAC gene
RC Cumming, JM Liu, H Youssoufian, M Buchwald
1021996
Blue cheese mutations define a novel, conserved gene involved in progressive neural degeneration
KD Finley, PT Edeen, RC Cumming, MD Mardahl-Dumesnil, BJ Taylor, ...
Journal of Neuroscience 23 (4), 1254-1264, 2003
942003
Attenuation of LDHA expression in cancer cells leads to redox-dependent alterations in cytoskeletal structure and cell migration
R Arseneault, A Chien, JT Newington, T Rappon, R Harris, RC Cumming
Cancer letters 338 (2), 255-266, 2013
912013
Aerobic glycolysis in the frontal cortex correlates with memory performance in wild-type mice but not the APP/PS1 mouse model of cerebral amyloidosis
RA Harris, L Tindale, A Lone, O Singh, SL Macauley, M Stanley, ...
Journal of Neuroscience 36 (6), 1871-1878, 2016
902016
Genetic Modifiers of the Drosophila Blue Cheese Gene Link Defects in Lysosomal Transport With Decreased Life Span and Altered Ubiquitinated-Protein Profiles
A Simonsen, RC Cumming, K Lindmo, V Galaviz, S Cheng, TE Rusten, ...
Genetics 176 (2), 1283-1297, 2007
882007
Age-dependent metabolic dysregulation in cancer and Alzheimer’s disease
RA Harris, L Tindale, RC Cumming
Biogerontology 15, 559-577, 2014
762014
Increase in expression levels and resistance to sulfhydryl oxidation of peroxiredoxin isoforms in amyloid β-resistant nerve cells
RC Cumming, R Dargusch, WH Fischer, D Schubert
Journal of biological chemistry 282 (42), 30523-30534, 2007
692007
Lactate preconditioning promotes a HIF-1α-mediated metabolic shift from OXPHOS to glycolysis in normal human diploid fibroblasts
AM Kozlov, A Lone, DH Betts, RC Cumming
Scientific reports 10 (1), 8388, 2020
522020
Aerobic glycolysis is required for spatial memory acquisition but not memory retrieval in mice
RA Harris, A Lone, H Lim, F Martinez, AK Frame, TJ Scholl, RC Cumming
Eneuro 6 (1), 2019
492019
High temperature tolerance and thermal plasticity in emerald ash borer Agrilus planipennis
S Sobek, A Rajamohan, D Dillon, RC Cumming, BJ Sinclair
Agricultural and Forest Entomology 13 (3), 333-340, 2011
452011
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Articles 1–20