Ambro van Hoof
Ambro van Hoof
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Exosome-mediated recognition and degradation of mRNAs lacking a termination codon
A Van Hoof, PA Frischmeyer, HC Dietz, R Parker
Science 295 (5563), 2262-2264, 2002
An mRNA surveillance mechanism that eliminates transcripts lacking termination codons
PA Frischmeyer, A Van Hoof, K O'Donnell, AL Guerrerio, R Parker, ...
Science 295 (5563), 2258-2261, 2002
Messenger RNA regulation: to translate or to degrade
AB Shyu, MF Wilkinson, A Van Hoof
The EMBO journal 27 (3), 471-481, 2008
Yeast exosome mutants accumulate 3′-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs
A van Hoof, P Lennertz, R Parker
Molecular and cellular biology 20 (2), 441-452, 2000
The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities
D Schaeffer, B Tsanova, A Barbas, FP Reis, EG Dastidar, ...
Nature structural & molecular biology 16 (1), 56-62, 2009
The exosome: a proteasome for RNA?
A van Hoof, R Parker
Cell 99 (4), 347-350, 1999
Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8 S, U4, U5, RNase MRP and RNase P RNAs in yeast
A van Hoof, P Lennertz, R Parker
The EMBO journal 19 (6), 1357-1365, 2000
Function of the ski4p (Csl4p) and Ski7p proteins in 3′-to-5′ degradation of mRNA
A van Hoof, RR Staples, RE Baker, R Parker
Molecular and cellular biology 20 (21), 8230-8243, 2000
Identification of BFN1, a bifunctional nuclease induced during leaf and stem senescence in Arabidopsis
MA Pérez-Amador, ML Abler, EJ De Rocher, DM Thompson, A van Hoof, ...
Plant physiology 122 (1), 169-180, 2000
Degradation of mRNAs that lack a stop codon: a decade of nonstop progress
AA Klauer, A van Hoof
Wiley Interdisciplinary Reviews: RNA 3 (5), 649-660, 2012
A riboswitch-containing sRNA controls gene expression by sequestration of a response regulator
S DebRoy, M Gebbie, A Ramesh, JR Goodson, MR Cruz, A Van Hoof, ...
Science 345 (6199), 937-940, 2014
Messenger RNA degradation: beginning at the end
A van Hoof, R Parker
Current Biology 12 (8), R285-R287, 2002
Premature nonsense codons decrease the stability of phytohemagglutinin mRNA in a position‐dependent manner
A van Hoof, PJ Green
The Plant Journal 10 (3), 415-424, 1996
The crystal structure of Mtr4 reveals a novel arch domain required for rRNA processing
RN Jackson, AA Klauer, BJ Hintze, H Robinson, A Van Hoof, SJ Johnson
The EMBO journal 29 (13), 2205-2216, 2010
Conserved functions of yeast genes support the duplication, degeneration and complementation model for gene duplication
A Van Hoof
Genetics 171 (4), 1455-1461, 2005
Yeast transcripts cleaved by an internal ribozyme provide new insight into the role of the cap and poly (A) tail in translation and mRNA decay
S Meaux, A Van Hoof
RNA 12 (7), 1323-1337, 2006
A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism
MA Wilson, S Meaux, A van Hoof
Genetics 177 (2), 773-784, 2007
Different nuclease requirements for exosome-mediated degradation of normal and nonstop mRNAs
D Schaeffer, A van Hoof
Proceedings of the National Academy of Sciences 108 (6), 2366-2371, 2011
Alternative splicing and subfunctionalization generates functional diversity in fungal proteomes
AN Marshall, MC Montealegre, C Jiménez-López, MC Lorenz, A van Hoof
PLoS genetics 9 (3), e1003376, 2013
Nonsense-mediated mRNA decay in yeast does not require PAB1 or a poly (A) tail
S Meaux, A van Hoof, KE Baker
Molecular cell 29 (1), 134-140, 2008
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