Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers T Gruosso, M Gigoux, VSK Manem, N Bertos, D Zuo, I Perlitch, SMI Saleh, ... The Journal of clinical investigation 129 (4), 1785-1800, 2019 | 367 | 2019 |
Single-cell spatial landscapes of the lung tumour immune microenvironment M Sorin, M Rezanejad, E Karimi, B Fiset, L Desharnais, LJM Perus, ... Nature 614 (7948), 548-554, 2023 | 165 | 2023 |
Report on computational assessment of tumor infiltrating lymphocytes from the International Immuno-Oncology Biomarker Working Group M Amgad, ES Stovgaard, E Balslev, J Thagaard, W Chen, S Dudgeon, ... NPJ breast cancer 6 (1), 16, 2020 | 139 | 2020 |
Predictive approaches for drug combination discovery in cancer SA Madani Tonekaboni, L Soltan Ghoraie, VSK Manem, B Haibe-Kains Briefings in bioinformatics 19 (2), 263-276, 2018 | 99 | 2018 |
Transcriptome‐wide association study reveals candidate causal genes for lung cancer Y Bossé, Z Li, J Xia, V Manem, R Carreras‐Torres, A Gabriel, ... International journal of cancer 146 (7), 1862-1878, 2020 | 55 | 2020 |
An interim report on the investigator-initiated phase 2 study of pembrolizumab immunological response evaluation (INSPIRE) DL Clouthier, SC Lien, SYC Yang, LT Nguyen, VSK Manem, D Gray, ... Journal for immunotherapy of cancer 7, 1-12, 2019 | 50 | 2019 |
MetaGxData: clinically annotated breast, ovarian and pancreatic cancer datasets and their use in generating a multi-cancer gene signature DMA Gendoo, M Zon, V Sandhu, VSK Manem, N Ratanasirigulchai, ... Scientific reports 9 (1), 8770, 2019 | 43 | 2019 |
Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility L Kachuri, M Johansson, SR Rashkin, RE Graff, Y Bossé, V Manem, ... Nature communications 11 (1), 27, 2020 | 32 | 2020 |
Modeling cellular response in large-scale radiogenomic databases to advance precision radiotherapy VSK Manem, M Lambie, I Smith, P Smirnov, V Kofia, M Freeman, ... Cancer research 79 (24), 6227-6237, 2019 | 32 | 2019 |
Single-cell spatial landscape of immunotherapy response reveals mechanisms of CXCL13 enhanced antitumor immunity M Sorin, E Karimi, M Rezanejad, WY Miranda, L Desharnais, ... Journal for Immunotherapy of Cancer 11 (2), 2023 | 29 | 2023 |
Modeling invasion dynamics with spatial random-fitness due to micro-environment VSK Manem, K Kaveh, M Kohandel, S Sivaloganathan PLoS One 10 (10), e0140234, 2015 | 29 | 2015 |
Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials J Hudeček, L Voorwerk, M van Seijen, I Nederlof, M de Maaker, ... NPJ Breast Cancer 6 (1), 15, 2020 | 28 | 2020 |
Tissue specificity of in vitro drug sensitivity F Yao, SA Madani Tonekaboni, Z Safikhani, P Smirnov, N El-Hachem, ... Journal of the American Medical Informatics Association 25 (2), 158-166, 2018 | 23 | 2018 |
Spatial invasion dynamics on random and unstructured meshes: Implications for heterogeneous tumor populations VSK Manem, M Kohandel, NL Komarova, S Sivaloganathan Journal of theoretical biology 349, 66-73, 2014 | 23 | 2014 |
Transcriptomic data helps refining classification of pulmonary carcinoid tumors with increased mitotic counts O Sazonova, V Manem, M Orain, B Khoshkrood-Mansoori, N Gaudreault, ... Modern Pathology 33 (9), 1712-1721, 2020 | 19 | 2020 |
ZNF768 links oncogenic RAS to cellular senescence R Villot, A Poirier, I Bakan, K Boulay, E Fernández, R Devillers, ... Nature Communications 12 (1), 4841, 2021 | 18 | 2021 |
The effect of radiation quality on the risks of second malignancies VSK Manem, M Kohandel, DC Hodgson, MB Sharpe, S Sivaloganathan International Journal of Radiation Biology 91 (3), 209-217, 2015 | 16 | 2015 |
Network science in clinical trials: A patient-centered approach VSK Manem, R Salgado, P Aftimos, C Sotiriou, B Haibe-Kains Seminars in cancer biology 52, 135-150, 2018 | 14 | 2018 |
Development and validation of genomic predictors of radiation sensitivity using preclinical data VSK Manem BMC cancer 21, 1-9, 2021 | 11 | 2021 |
RadiationGeneSigDB: a database of oxic and hypoxic radiation response gene signatures and their utility in pre-clinical research VSK Manem, A Dhawan The British Journal of Radiology 92 (1103), 20190198, 2019 | 11 | 2019 |