| Dimorphic effects of Notch signaling in bone homeostasis F Engin, Z Yao, T Yang, G Zhou, T Bertin, MM Jiang, Y Chen, L Wang, ... Nature medicine 14 (3), 299-305, 2008 | 471 | 2008 |
| Dominance of SOX9 function over RUNX2 during skeletogenesis G Zhou, Q Zheng, F Engin, E Munivez, Y Chen, E Sebald, D Krakow, ... Proceedings of the National Academy of Sciences 103 (50), 19004-19009, 2006 | 413 | 2006 |
| Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes F Engin, A Yermalovich, T Nguyen, S Hummasti, W Fu, DL Eizirik, ... Science translational medicine 5 (211), 211ra156-211ra156, 2013 | 305 | 2013 |
| Restoring endoplasmic reticulum function by chemical chaperones: an emerging therapeutic approach for metabolic diseases F Engin, GS Hotamisligil Diabetes, obesity and metabolism 12, 108-115, 2010 | 276 | 2010 |
| Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms F Brozzi, TR Nardelli, M Lopes, I Millard, J Barthson, M Igoillo-Esteve, ... Diabetologia 58, 2307-2316, 2015 | 227 | 2015 |
| Notch signaling contributes to the pathogenesis of human osteosarcomas F Engin, T Bertin, O Ma, MM Jiang, L Wang, RE Sutton, LA Donehower, ... Human molecular genetics 18 (8), 1464-1470, 2009 | 196 | 2009 |
| Aberrant islet unfolded protein response in type 2 diabetes F Engin, T Nguyen, A Yermalovich, GS Hotamisligil Scientific reports 4 (1), 4054, 2014 | 113 | 2014 |
| NOTCHing the bone: insights into multi-functionality F Engin, B Lee Bone 46 (2), 274-280, 2010 | 112 | 2010 |
| Beta cell dedifferentiation induced by IRE1α deletion prevents type 1 diabetes H Lee, YS Lee, Q Harenda, S Pietrzak, HZ Oktay, S Schreiber, Y Liao, ... Cell metabolism 31 (4), 822-836. e5, 2020 | 104 | 2020 |
| ER stress and development of type 1 diabetes F Engin Journal of Investigative Medicine 64 (1), 2-6, 2016 | 90 | 2016 |
| A hormone complex of FABP4 and nucleoside kinases regulates islet function KJ Prentice, J Saksi, LT Robertson, GY Lee, KE Inouye, K Eguchi, A Lee, ... Nature 600 (7890), 720-726, 2021 | 48 | 2021 |
| E-selectin ligand–1 regulates growth plate homeostasis in mice by inhibiting the intracellular processing and secretion of mature TGF-β T Yang, R Mendoza-Londono, H Lu, J Tao, K Li, B Keller, MM Jiang, ... The Journal of clinical investigation 120 (7), 2474-2485, 2010 | 42 | 2010 |
| Adaptation to chronic ER stress enforces pancreatic β-cell plasticity CW Chen, BJ Guan, MR Alzahrani, Z Gao, L Gao, S Bracey, J Wu, ... Nature communications 13 (1), 4621, 2022 | 39 | 2022 |
| Uncoupling of metabolic health from longevity through genetic alteration of adipose tissue lipid-binding proteins KN Charles, MD Li, F Engin, AP Arruda, K Inouye, GS Hotamisligil Cell reports 21 (2), 393-402, 2017 | 32 | 2017 |
| Heterogeneity of diabetes: β-cells, phenotypes, and precision medicine: proceedings of an international symposium of the Canadian Institutes of Health Research’s Institute of … WT Cefalu, DK Andersen, G Arreaza-Rubín, CL Pin, S Sato, CB Verchere, ... Diabetes 71 (1), 1-22, 2022 | 30 | 2022 |
| An accomplice more than a mere victim: the impact of β-cell ER stress on type 1 diabetes pathogenesis GS Sahin, H Lee, F Engin Molecular metabolism 54, 101365, 2021 | 29 | 2021 |
| The Inhibitory G Protein α-Subunit, Gαz, Promotes Type 1 Diabetes-Like Pathophysiology in NOD Mice RJ Fenske, MT Cadena, QE Harenda, HN Wienkes, K Carbajal, ... Endocrinology 158 (6), 1645-1658, 2017 | 26 | 2017 |
| Preparing highly viable single-cell suspensions from mouse pancreatic islets for single-cell RNA sequencing H Lee, F Engin STAR protocols 1 (3), 100144, 2020 | 12 | 2020 |
| Differential expression of ormdl genes in the islets of mice and humans with obesity H Lee, RJ Fenske, T Akcan, E Domask, DB Davis, ME Kimple, F Engin Iscience 23 (7), 2020 | 11 | 2020 |
| Stress-induced β cell early senescence confers protection against type 1 diabetes H Lee, GS Sahin, CW Chen, S Sonthalia, SM Cañas, HZ Oktay, ... Cell Metabolism 35 (12), 2200-2215. e9, 2023 | 7 | 2023 |
