Macrophages in atherosclerosis: a dynamic balance KJ Moore, FJ Sheedy, EA Fisher Nature Reviews Immunology 13 (10), 709-721, 2013 | 2586 | 2013 |
Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21 FJ Sheedy, E Palsson-McDermott, EJ Hennessy, C Martin, JJ O'leary, ... Nature immunology 11 (2), 141-147, 2010 | 1187 | 2010 |
Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages EM Palsson-McDermott, AM Curtis, G Goel, MAR Lauterbach, FJ Sheedy, ... Cell metabolism 21 (1), 65-80, 2015 | 1112 | 2015 |
MicroRNAs: the fine-tuners of Toll-like receptor signalling LA O'neill, FJ Sheedy, CE McCoy Nature reviews immunology 11 (3), 163-175, 2011 | 1046 | 2011 |
CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation FJ Sheedy, A Grebe, KJ Rayner, P Kalantari, B Ramkhelawon, ... Nature immunology 14 (8), 812-820, 2013 | 931 | 2013 |
Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides KJ Rayner, CC Esau, FN Hussain, AL McDaniel, SM Marshall, ... Nature 478 (7369), 404-407, 2011 | 825 | 2011 |
Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis KJ Rayner, FJ Sheedy, CC Esau, FN Hussain, RE Temel, S Parathath, ... The Journal of clinical investigation 121 (7), 2921-2931, 2011 | 811 | 2011 |
Turning 21: induction of miR-21 as a key switch in the inflammatory response FJ Sheedy Frontiers in immunology 6, 119312, 2015 | 489 | 2015 |
MicroRNA-33–dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis M Ouimet, HN Ediriweera, UM Gundra, FJ Sheedy, B Ramkhelawon, ... The Journal of clinical investigation 125 (12), 4334-4348, 2015 | 361 | 2015 |
Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism M Ouimet, S Koster, E Sakowski, B Ramkhelawon, C Van Solingen, ... Nature immunology 17 (6), 677-686, 2016 | 349 | 2016 |
IL-10 inhibits miR-155 induction by toll-like receptors CE McCoy, FJ Sheedy, JE Qualls, SL Doyle, SR Quinn, PJ Murray, ... Journal of Biological Chemistry 285 (27), 20492-20498, 2010 | 340 | 2010 |
Cutting edge: Mycobacterium tuberculosis induces aerobic glycolysis in human alveolar macrophages that is required for control of intracellular bacillary replication LE Gleeson, FJ Sheedy, EM Palsson-McDermott, D Triglia, SM O’Leary, ... The Journal of Immunology 196 (6), 2444-2449, 2016 | 288 | 2016 |
Adding fuel to fire: microRNAs as a new class of mediators of inflammation FJ Sheedy, LAJ O’Neill Annals of the rheumatic diseases 67 (Suppl 3), iii50-iii55, 2008 | 286 | 2008 |
Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity B Ramkhelawon, EJ Hennessy, M Ménager, TD Ray, FJ Sheedy, ... Nature medicine 20 (4), 377-384, 2014 | 274 | 2014 |
Platelet microparticles reprogram macrophage gene expression and function B Laffont, A Corduan, M Rousseau, AC Duchez, CHC Lee, E Boilard, ... Thrombosis and haemostasis 115 (02), 311-323, 2016 | 182 | 2016 |
Mycobacterium tuberculosis limits host glycolysis and IL-1β by restriction of PFK-M via MicroRNA-21 EE Hackett, H Charles-Messance, SM O’Leary, LE Gleeson, ... Cell reports 30 (1), 124-136. e4, 2020 | 117 | 2020 |
The Troll in Toll: Mal and Tram as bridges for TLR2 and TLR4 signaling FJ Sheedy, LAJ O’Neill Journal of Leucocyte Biology 82 (2), 196-203, 2007 | 98 | 2007 |
Toll-like receptor-4 (TLR4) down-regulates microRNA-107, increasing macrophage adhesion via cyclin-dependent kinase 6 EJ Hennessy, FJ Sheedy, D Santamaria, M Barbacid, LAJ O'Neill Journal of Biological Chemistry 286 (29), 25531-25539, 2011 | 74 | 2011 |
IL-1 signaling in atherosclerosis: sibling rivalry FJ Sheedy, KJ Moore Nature immunology 14 (10), 1030-1032, 2013 | 70 | 2013 |
Metabolic reprogramming & inflammation: Fuelling the host response to pathogens LE Gleeson, FJ Sheedy Seminars in immunology 28 (5), 450-468, 2016 | 68 | 2016 |