|In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project|
RS Judson, KA Houck, RJ Kavlock, TB Knudsen, MT Martin, ...
Environmental health perspectives 118 (4), 485-492, 2010
|Update on EPA’s ToxCast program: providing high throughput decision support tools for chemical risk management|
R Kavlock, K Chandler, K Houck, S Hunter, R Judson, N Kleinstreuer, ...
Chemical research in toxicology 25 (7), 1287-1302, 2012
|Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment|
BA Wetmore, JF Wambaugh, SS Ferguson, MA Sochaski, DM Rotroff, ...
Toxicological Sciences 125 (1), 157-174, 2012
|Incorporating Human Dosimetry and Exposure into High-Throughput In Vitro Toxicity Screening|
DM Rotroff, BA Wetmore, DJ Dix, SS Ferguson, HJ Clewell, KA Houck, ...
Toxicological Sciences 117 (2), 348-358, 2010
|Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor|
RS Judson, FM Magpantay, V Chickarmane, C Haskell, N Tania, J Taylor, ...
Toxicological Sciences 148 (1), 137-154, 2015
|Analysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activity|
RS Judson, MT Martin, DM Reif, KA Houck, TB Knudsen, DM Rotroff, ...
Environmental science & technology 44 (15), 5979-5985, 2010
|Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA’s ToxCast program|
MT Martin, DJ Dix, RS Judson, RJ Kavlock, DM Reif, AM Richard, ...
Chemical research in toxicology 23 (3), 578-590, 2010
|Metabolic network failures in Alzheimer's disease: A biochemical road map|
JB Toledo, M Arnold, G Kastenmüller, R Chang, RA Baillie, X Han, ...
Alzheimer's & Dementia 13 (9), 965-984, 2017
|Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space|
R Judson, K Houck, M Martin, AM Richard, TB Knudsen, I Shah, S Little, ...
Toxicological Sciences 152 (2), 323-339, 2016
|Using in Vitro High Throughput Screening Assays to Identify Potential Endocrine-Disrupting Chemicals|
DM Rotroff, DJ Dix, KA Houck, TB Knudsen, MT Martin, KW McLaurin, ...
Environmental health perspectives 121 (1), 7-14, 2013
|Profiling the reproductive toxicity of chemicals from multigeneration studies in the toxicity reference database|
MT Martin, E Mendez, DG Corum, RS Judson, RJ Kavlock, DM Rotroff, ...
Toxicological Sciences 110 (1), 181-190, 2009
|Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway|
R Huang, S Sakamuru, MT Martin, DM Reif, RS Judson, KA Houck, ...
Scientific reports 4, 5664, 2014
|Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome|
S MahmoudianDehkordi, M Arnold, K Nho, S Ahmad, W Jia, G Xie, ...
Alzheimer's & Dementia 15 (1), 76-92, 2019
|Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin|
K Zhou, SW Yee, EL Seiser, N Van Leeuwen, R Tavendale, AJ Bennett, ...
Nature genetics 48 (9), 1055-1059, 2016
|Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen|
MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, ...
Nature communications 10 (1), 1-17, 2019
|Predictive Endocrine Testing in the 21st Century Using in Vitro Assays of Estrogen Receptor Signaling Responses|
DM Rotroff, MT Martin, DJ Dix, DL Filer, KA Houck, TB Knudsen, NS Sipes, ...
Environmental science & technology 48 (15), 8706-8716, 2014
|Development of a thyroperoxidase inhibition assay for high-throughput screening|
KB Paul, JM Hedge, DM Rotroff, MW Hornung, KM Crofton, SO Simmons
Chemical research in toxicology 27 (3), 387-399, 2014
|Xenobiotic-metabolizing enzyme and transporter gene expression in primary cultures of human hepatocytes modulated by ToxCast chemicals|
DM Rotroff, AL Beam, DJ Dix, A Farmer, KM Freeman, KA Houck, ...
Journal of Toxicology and Environmental Health, Part B 13 (2-4), 329-346, 2010
|Binary classification of a large collection of environmental chemicals from estrogen receptor assays by quantitative structure–activity relationship and machine learning methods|
Q Zang, DM Rotroff, RS Judson
Journal of chemical information and modeling 53 (12), 3244-3261, 2013
|Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: new mechanistic insights for rapid acting …|
DM Rotroff, DG Corum, A Motsinger-Reif, O Fiehn, N Bottrel, WC Drevets, ...
Translational psychiatry 6 (9), e894-e894, 2016