| How mutational epistasis impairs predictability in protein evolution and design CM Miton, N Tokuriki Protein Science 25 (7), 1260-1272, 2016 | 209 | 2016 |
| A mechanistic view of enzyme evolution G Yang, CM Miton, N Tokuriki Protein Science 29 (8), 1724-1747, 2020 | 72 | 2020 |
| Epistasis and intramolecular networks in protein evolution CM Miton, K Buda, N Tokuriki Current Opinion in Structural Biology 69 (August 2021), 160-168, 2021 | 69 | 2021 |
| Cryptic genetic variation shapes the adaptive evolutionary potential of enzymes F Baier, N Hong, G Yang, A Pabis, CM Miton, A Barrozo, PD Carr, ... Elife 8, e40789, 2019 | 48 | 2019 |
| Mechanistic understanding enables the rational design of salicylanilide combination therapies for Gram-negative infections JN Copp, D Pletzer, AS Brown, J Van der Heijden, CM Miton, RJ Edgar, ... MBio 11 (5), 10.1128/mbio. 02068-20, 2020 | 37 | 2020 |
| Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset CM Miton, S Jonas, G Fischer, F Duarte, MF Mohamed, B van Loo, ... Proceedings of the National Academy of Sciences 115 (31), E7293-E7302, 2018 | 37 | 2018 |
| Insertions and deletions (indels): a missing piece of the protein engineering jigsaw CM Miton, N Tokuriki Biochemistry 62 (2), 148-157, 2022 | 26 | 2022 |
| Statistical analysis of mutational epistasis to reveal intramolecular interaction networks in proteins CM Miton, JZ Chen, K Ost, DW Anderson, N Tokuriki Methods in Enzymology 643, 243-280, 2020 | 26 | 2020 |
| Molecular determinants of protein evolvability K Buda, CM Miton, XC Fan, N Tokuriki Trends in Biochemical Sciences 48 (9), 751-760, 2023 | 22 | 2023 |
| Pervasive epistasis exposes intramolecular networks in adaptive enzyme evolution K Buda, CM Miton, N Tokuriki Nature Communications 14 (1), 8508, 2023 | 19* | 2023 |
| Leveraging ancestral sequence reconstruction for protein representation learning DS Matthews, MA Spence, AC Mater, J Nichols, SB Pulsford, M Sandhu, ... Nature Machine Intelligence 6 (12), 1542-1555, 2024 | 6 | 2024 |
| Origin of evolutionary bifurcation in an enzyme CM Miton, EC Campbell, JA Kaczmarski, F Feixas, A Romero-Rivera, ... bioRxiv, 2023.11. 25.568631, 2023 | 2 | 2023 |
| Ultrahigh-throughput discovery of promiscuous enzymes by picodroplet functional metagenomics PY Colin, B Kintses, F Gielen, CM Miton, G Fischer, MF Mohamed, ... Nature communications 6 (1), 10008, 2015 | | 2015 |
Nobuhiko TokurikiUniversity of British ColumbiaVerified email at msl.ubc.ca
